Search Results - "Hou, Si‐Hua"

Deconstructive Asymmetric Total Synthesis of Morphine‐Family Alkaloid (−)‐Thebainone A by Hou, Si‐Hua, Prichina, Adriana Y., Dong, Guangbin

“…Herein, we describe the development of a deconstructive strategy for the first asymmetric synthesis of (−)‐thebainone A, capitalizing on an enantioselective…”
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Asymmetric Total Syntheses of Di‐ and Sesquiterpenoids by Catalytic C−C Activation of Cyclopentanones by Hou, Si‐Hua, Prichina, Adriana Y., Zhang, Mengxi, Dong, Guangbin

“…To show the synthetic utility of the catalytic C−C activation of less strained substrates, described here are the collective and concise syntheses of the…”
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Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products by Li, Quan‐Zhe, Hou, Si‐Hua, Kang, Jun‐Chen, Lian, Peng‐Fei, Hao, Yu, Chen, Chao, Zhou, Jia, Ding, Tong‐Mei, Zhang, Shu‐Yu

“…Bioinspired palladium‐catalyzed intramolecular cyclization of amino acid derivatives containing a vinyl iodide moiety by C−H activation enabled rapid access to…”
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Divergent and Efficient Syntheses of the Lycopodium Alkaloids (−)-Lycojaponicumin C, (−)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine by Hou, Si-Hua, Tu, Yong-Qiang, Liu, Lin, Zhang, Fu-Min, Wang, Shao-Hua, Zhang, Xiao-Ming

“…Four from one: The four title alkaloids (structures shown in blue box) have been synthesized by using a common versatile intermediate with a 6/5/5 tricyclic…”
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Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone B by Hou, Si-Hua, Tu, Yong-Qiang, Wang, Shuang-Hu, Xi, Chao-Chao, Zhang, Fu-Min, Wang, Shao-Hua, Li, Yan-Tao, Liu, Lin

“…Total syntheses of the biologically important and structurally unique tetracyclic diterpenes conidiogenone, conidiogenol, and conidiogenone B of the cyclopiane…”
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Deconstructive and Divergent Synthesis of Bioactive Natural Products by Hou, Si-Hua, Zhou, Feng-Fan, Sun, Yi-Hang, Li, Quan-Zhe

“…Natural products play a key role in innovative drug discovery. To explore the potential application of natural products and their analogues in pharmacology,…”
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Total Synthesis of the Nominal Didemnaketal A by Zhang, Fu-Min, Peng, Lei, Li, Hui, Ma, Ai-Jun, Peng, Jin-Bao, Guo, Jing-Jing, Yang, Dengtao, Hou, Si-Hua, Tu, Yong-Qiang, Kitching, William

“…False identity: The synthesis of a natural product described by Faulkner and co‐workers two decades ago has revealed the need for the revision of some…”
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Rhodium-Catalyzed Diastereo- and Enantioselective Divergent Annulations between Cyclobutanones and 1,5-Enynes: Rapid Construction of Complex C(sp3)‑Rich Scaffolds by Hou, Si-Hua, Yu, Xuan, Zhang, Rui, Wagner, Cole, Dong, Guangbin

“…Given the emerging demand to “escape from flatland” for drug discovery, synthetic methods that can efficiently construct complex three-dimensional structures…”
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Enantioselective Type II Cycloaddition of Alkynes via C–C Activation of Cyclobutanones: Rapid and Asymmetric Construction of [3.3.1] Bridged Bicycles by Hou, Si-Hua, Yu, Xuan, Zhang, Rui, Deng, Lin, Zhang, Mengxi, Prichina, Adriana Y, Dong, Guangbin

“…Synthesis of bridged scaffolds via Type II cyclization constitutes substantial challenges due to the intrinsic ring strain accumulated in reaction transition…”
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Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids by Zhang, Ting-Yu, Lin, Jun-Bing, Li, Quan-Zhe, Kang, Jun-Chen, Pan, Jin-Long, Hou, Si-Hua, Chen, Chao, Zhang, Shu-Yu

“…An efficient and convenient copper-catalyzed method has been developed to achieve direct ortho-C–H/N-H annulation to synthesize phenanthridinones with arynes…”
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Expansion of Structure Property in Cascade Nazarov Cyclization and Cycloexpansion Reaction to Diverse Angular Tricycles and Total Synthesis of Nominal Madreporanone by Fang, Kun, Dou, Bao-Heng, Zhang, Fu-Min, Wang, Yun-Peng, Shan, Zi-Rui, Wang, Xiao-Yu, Hou, Si-Hua, Tu, Yongqiang, Ding, Tong-Mei

“…A cascade Nazarov cyclization/dicycloexpansions reaction was developed for the precise synthesis of the angularly fused M/5/N (M = 5, 6; N = 4-9, 13) tricyclic…”
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Asymmetric N‑Hydroxyalkylation of Indoles with Ethyl Glyoxalates Catalyzed by a Chiral Phosphoric Acid: Highly Enantioselective Synthesis of Chiral N,O-Aminal Indole Derivatives by Wang, Le, Zhou, Jia, Ding, Tong-Mei, Yan, Zhi-Qiang, Hou, Si-Hua, Zhu, Guo-Dong, Zhang, Shu-Yu

“…A method of SPINOL-derived chiral phosphoric acid catalyzed asymmetric intermolecular N-hydroxyalkylation of multisubstituted indoles with ethyl glyoxalates is…”
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Total Syntheses of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds by Yin, Jun-Jie, Wang, Yun-Peng, Xue, Jun, Zhou, Feng-Fan, Shan, Xing-Qian, Zhu, Rong, Fang, Kun, Shi, Lei, Zhang, Shu-Yu, Hou, Si-Hua, Xia, Wujiong, Tu, Yong-Qiang

“…The first total syntheses of polycyclic diterpenes phomopsene (1), methyl phomopsenonate (2), and iso-phomopsene (3) have been accomplished through the unusual…”
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Deconstructive Asymmetric Total Synthesis of Morphine‐Family Alkaloid (−)‐Thebainone A by Hou, Si‐Hua, Prichina, Adriana Y., Dong, Guangbin

“…Herein, we describe the development of a deconstructive strategy for the first asymmetric synthesis of (−)‐thebainone A, capitalizing on an enantioselective…”
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Asymmetric Total Syntheses of Di‐ and Sesquiterpenoids by Catalytic C−C Activation of Cyclopentanones by Hou, Si‐Hua, Prichina, Adriana Y., Zhang, Mengxi, Dong, Guangbin

“…To show the synthetic utility of the catalytic C−C activation of less strained substrates, described here are the collective and concise syntheses of the…”
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Total Synthesis of (−)-FR901483 by Ma, Ai-Jun, Tu, Yong-Qiang, Peng, Jin-Bao, Dou, Qing-Yun, Hou, Si-Hua, Zhang, Fu-Min, Wang, Shao-Hua

“…A total synthesis of the immunosuppressive alkaloid (−)-FR901483 (1) has been described. The intriguingly azatricyclic structure of 1 was constructed by the…”
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Total Synthesis of the Nominal Didemnaketal A by Zhang, Fu-Min, Peng, Lei, Li, Hui, Ma, Ai-Jun, Peng, Jin-Bao, Guo, Jing-Jing, Yang, Dengtao, Hou, Si-Hua, Tu, Yong-Qiang, Kitching, William

“…Falsche Identität: Die Synthese eines Naturstoffs, den Faulkner und Mitarbeiter vor zwei Jahrzehnten beschrieben, machte die Revision einiger stereochemischer…”
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Bioinspired Palladium‐Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products by Li, Quan‐Zhe, Hou, Si‐Hua, Kang, Jun‐Chen, Lian, Peng‐Fei, Hao, Yu, Chen, Chao, Zhou, Jia, Ding, Tong‐Mei, Zhang, Shu‐Yu

“…Bioinspired palladium‐catalyzed intramolecular cyclization of amino acid derivatives containing a vinyl iodide moiety by C−H activation enabled rapid access to…”
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Frontispiece: Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone B by Hou, Si-Hua, Tu, Yong-Qiang, Wang, Shuang-Hu, Xi, Chao-Chao, Zhang, Fu-Min, Wang, Shao-Hua, Li, Yan-Tao, Liu, Lin

“…Total Synthesis. By installing a SPh “directing” group on the expected migratory carbon of the precursor, Y.‐Q. Tu and co‐workers in their Communication on…”
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Frontispiz: Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone B by Hou, Si-Hua, Tu, Yong-Qiang, Wang, Shuang-Hu, Xi, Chao-Chao, Zhang, Fu-Min, Wang, Shao-Hua, Li, Yan-Tao, Liu, Lin

“…Totalsynthese. Die Einführung einer dirigierenden SPh‐Gruppe am migratorischen Kohlenstoff des Vorstufenmoleküls war entscheidend in der ersten Totalsynthese…”
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