Search Results - "Hou, Mimi M."

Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens by Barrett, Jordan R, Silk, Sarah E, Mkindi, Catherine G, Kwiatkowska, Karolina M, Hou, Mimi M, Lias, Amelia M, Kalinga, Wilmina F, Mtaka, Ivanny M, McHugh, Kirsty, Bardelli, Martino, Davies, Hannah, King, Lloyd D W, Edwards, Nick J, Chauhan, Virander S, Mukherjee, Paushali, Rwezaula, Stella, Chitnis, Chetan E, Olotu, Ally I, Minassian, Angela M, Draper, Simon J, Nielsen, Carolyn M

“…We have previously reported primary endpoints of a clinical trial testing two vaccine platforms for the delivery of malaria DBPRII: viral vectors (ChAd63,…”
Get full text

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial by Martinez, Francisco J., White, Michael, Guillotte-Blisnick, Micheline, Huon, Christèle, Boucharlat, Alix, Agou, Fabrice, England, Patrick, Popovici, Jean, Hou, Mimi M., Silk, Sarah E., Barrett, Jordan R., Nielsen, Carolyn M., Reimer, Jenny M., Mukherjee, Paushali, Chauhan, Virander S., Minassian, Angela M., Draper, Simon J., Chitnis, Chetan E.

“…The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate…”
Get full text

Higher HIV-1 evolutionary rate is associated with cytotoxic T lymphocyte escape mutations in infants by Nazziwa, Jamirah, Andrews, Sophie M, Hou, Mimi M, Bruhn, Christian A W, Garcia-Knight, Miguel A, Slyker, Jennifer, Hill, Sarah, Lohman Payne, Barbara, Moringas, Dorothy, Lemey, Philippe, John-Stewart, Grace, Rowland-Jones, Sarah L, Esbjörnsson, Joakim

“…Escape from cytotoxic T lymphocyte (CTL) responses toward HIV-1 Gag and Nef has been associated with reduced control of HIV-1 replication in adults. However,…”
Get more information

Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development by Mertens, Jonas E., Rigby, Cassandra A., Bardelli, Martino, Quinkert, Doris, Hou, Mimi M., Diouf, Ababacar, Silk, Sarah E., Chitnis, Chetan E., Minassian, Angela M., Moon, Robert W., Long, Carole A., Draper, Simon J., Miura, Kazutoyo

“…•The PkGIA will be an essential selection tool for P. vivax vaccine development.•The error of the assay was evaluated with human anti-PvDBPII…”
Get full text

Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection by Hou, Mimi M, Barrett, Jordan R, Themistocleous, Yrene, Rawlinson, Thomas A, Diouf, Ababacar, Martinez, Francisco J, Nielsen, Carolyn M, Lias, Amelia M, King, Lloyd D W, Edwards, Nick J, Greenwood, Nicola M, Kingham, Lucy, Poulton, Ian D, Khozoee, Baktash, Goh, Cyndi, Hodgson, Susanne H, Mac Lochlainn, Dylan J, Salkeld, Jo, Guillotte-Blisnick, Micheline, Huon, Christèle, Mohring, Franziska, Reimer, Jenny M, Chauhan, Virander S, Mukherjee, Paushali, Biswas, Sumi, Taylor, Iona J, Lawrie, Alison M, Cho, Jee-Sun, Nugent, Fay L, Long, Carole A, Moon, Robert W, Miura, Kazutoyo, Silk, Sarah E, Chitnis, Chetan E, Minassian, Angela M, Draper, Simon J

“…There are no licensed vaccines against . We conducted two phase 1/2a clinical trials to assess two vaccines targeting Duffy-binding protein region II…”
Get more information

Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics by Salkeld, Jo, Themistocleous, Yrene, Barrett, Jordan R., Mitton, Celia H., Rawlinson, Thomas A., Payne, Ruth O., Hou, Mimi M., Khozoee, Baktash, Edwards, Nick J., Nielsen, Carolyn M., Sandoval, Diana Muñoz, Bach, Florian A., Nahrendorf, Wiebke, Ramon, Raquel Lopez, Baker, Megan, Ramos-Lopez, Fernando, Folegatti, Pedro M., Quinkert, Doris, Ellis, Katherine J., Poulton, Ian D., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Spence, Philip J., Silk, Sarah E., Draper, Simon J., Minassian, Angela M.

“…In endemic settings it is known that natural malaria immunity is gradually acquired following repeated exposures. Here we sought to assess whether similar…”
Get full text

Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, Sarah E, Kalinga, Wilmina F, Salkeld, Jo, Mtaka, Ivanny M, Ahmed, Saumu, Milando, Florence, Diouf, Ababacar, Bundi, Caroline K, Balige, Neema, Hassan, Omar, Mkindi, Catherine G, Rwezaula, Stella, Athumani, Thabit, Mswata, Sarah, Lilolime, Nasoro S, Simon, Beatus, Msami, Hania, Mohamed, Mohamed, David, Damiano M, Mohammed, Latipha, Nyaulingo, Gloria, Mwalimu, Bakari, Juma, Omary, Mwamlima, Tunu G, Sasamalo, Ibrahim A, Mkumbange, Rose P, Kamage, Janeth J, Barrett, Jordan R, King, Lloyd D W, Hou, Mimi M, Pulido, David, Carnrot, Cecilia, Lawrie, Alison M, Cowan, Rachel E, Nugent, Fay L, Roberts, Rachel, Cho, Jee-Sun, Long, Carole A, Nielsen, Carolyn M, Miura, Kazutoyo, Draper, Simon J, Olotu, Ally I, Minassian, Angela M

“…A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by…”
Get full text

Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly by Minassian, Angela M, Themistocleous, Yrene, Silk, Sarah E, Barrett, Jordan R, Kemp, Alison, Quinkert, Doris, Nielsen, Carolyn M, Edwards, Nick J, Rawlinson, Thomas A, Ramos Lopez, Fernando, Roobsoong, Wanlapa, Ellis, Katherine Jd, Cho, Jee-Sun, Aunin, Eerik, Otto, Thomas D, Reid, Adam J, Bach, Florian A, Labbé, Geneviève Mc, Poulton, Ian D, Marini, Arianna, Zaric, Marija, Mulatier, Margaux, Lopez Ramon, Raquel, Baker, Megan, Mitton, Celia H, Sousa, Jason C, Rachaphaew, Nattawan, Kumpitak, Chalermpon, Maneechai, Nongnuj, Suansomjit, Chayanut, Piteekan, Tianrat, Hou, Mimi M, Khozoee, Baktash, McHugh, Kirsty, Roberts, David J, Lawrie, Alison M, Blagborough, Andrew M, Nugent, Fay L, Taylor, Iona J, Johnson, Kimberly J, Spence, Philip J, Sattabongkot, Jetsumon, Biswas, Sumi, Rayner, Julian C, Draper, Simon J

“…Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept…”
Get full text