Search Results - "Hottot, A"

Model predictive control during the primary drying stage of lyophilisation by Daraoui, N., Dufour, P., Hammouri, H., Hottot, A.

“…During the primary drying stage of pharmaceutical solutions in vial, the sublimation front is the boundary between the dried and frozen layers that moves from…”
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Determination of mass and heat transfer parameters during freeze-drying cycles of pharmaceutical products by Hottot, A, Vessot, S, Andrieu, J

“…The principal aim of this study was to evaluate the water vapour mass transfer resistance of the dried layer and the vial heat transfer coefficient values of a…”
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Experimental Study and Modeling of Freeze-Drying in Syringe Configuration. Part II: Mass and Heat Transfer Parameters and Sublimation End-Points by Hottot, A., Andrieu, J., Hoang, V., Shalaev, E. Y., Gatlin, L. A., Ricketts, S.

“…This work concerns the experimental study in syringe configuration of the sublimation period for a model formulation under operating conditions commonly used…”
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Experimental Study and Modeling of Freeze-Drying in Syringe Configuration. Part I: Freezing Step by Hottot, A., Andrieu, J., Vessot, S., Shalaev, E., Gatlin, L. A., Ricketts, S.

“…This article concerns the experimental study and the modeling of the freezing step during freeze-drying of a model lyoprotectant formulation in syringe…”
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Thermophysical properties of aqueous and frozen states of BSA/water/Tris systems by Hottot, A., Daoussi, R., Andrieu, J.

“…In the modelling and the optimization of pharmaceutical protein freeze–drying processes, thermophysical properties values of the formulation in frozen or in…”
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Freeze-Drying of Pharmaceutical Proteins in Vials: Modeling of Freezing and Sublimation Steps by Hottot, Aurélie, Peczalski, Roman, Vessot, Séverine, Andrieu, Julien

“…The commercial finite element code FEMLAB was used to perform two-dimensional axisymmetric simulations of the temperature profiles and the moving front…”
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A Direct Characterization Method of the Ice Morphology. Relationship Between Mean Crystals Size and Primary Drying Times of Freeze-Drying Processes by Hottot, Aurélie, Vessot, Séverine, Andrieu, Julien

“…In the freeze-drying process, the freezing step is one of the most important steps which determines the texture of the frozen material and, consequently, the…”
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Optimal operation of sublimation time of the freeze drying process by predictive control: Application of the MPC@CB software by Daraoui, N., Dufour, P., Hammouri, H., Hottot, A.

“…This paper presents the application of a model based predictive control strategy for the primary stage of the freeze drying process, which has not been tackled…”
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