Search Results - "Hottinger, A F"

Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma by Hottinger, A F, Aissa, A B, Espeli, V, Squiban, D, Dunkel, N, Vargas, M I, Hundsberger, T, Mach, N, Schaller, K, Weber, D C, Bodmer, A, Dietrich, P-Y

“…Background: Sorafenib (Sb) is a multiple kinase inhibitor targeting both tumour cell proliferation and angiogenesis that may further act as a potent…”
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Next generation sequencing in adult patients with glioblastoma in Switzerland: a multi-centre decision analysis by Zeitlberger, A. M., Putora, P. M., Hofer, S., Schucht, P., Migliorini, D., Hottinger, A. F., Roelcke, U., Läubli, H., Spina, P., Bozinov, O., Weller, M., Neidert, M. C., Hundsberger, T.

“…Background Glioblastoma is the most common malignant primary brain tumour in adults and driven by various genomic alterations. Next generation sequencing (NGS)…”
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Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers by Stupp, R., Hottinger, A. F., van den Bent, M. J., Dietrich, P. -Y., Brandes, A. A.

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Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus by Hottinger, Andreas F, Azzouz, Mimoun, Deglon, Nicole, Aebischer, Patrick, Zurn, Anne D

“…To date, delivery of neurotrophic factors has only allowed to transiently protect axotomized facial motoneurons against cell death. In the present report,…”
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Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial by Wirsching, H.-G., Tabatabai, G., Roelcke, U., Hottinger, A.F., Jörger, F., Schmid, A., Plasswilm, L., Schrimpf, D., Mancao, C., Capper, D., Conen, K., Hundsberger, T., Caparrotti, F., von Moos, R., Riklin, C., Felsberg, J., Roth, P., Jones, D.T.W., Pfister, S., Rushing, E.J., Abrey, L., Reifenberger, G., Held, L., von Deimling, A., Ochsenbein, A., Weller, M.

“…The addition of bevacizumab to temozolomide-based chemoradiotherapy (TMZ/RT → TMZ) did not prolong overall survival (OS) in patients with newly diagnosed…”
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Leptomeningeal tumor response to combined MAPK/ERK inhibition in V600E-mutated gliomas despite undetectable CSF drug levels by Hottinger, A.F., Bensaid, D., De Micheli, R., Moura, B., Mokhtari, K., Cardoso, E., Idbaih, A., Stupp, R.

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Malignant PRES and RCVS after brain surgery in the early postpartum period by Cossu, G, Daniel, R.T, Hottinger, A.F, Maduri, R, Messerer, M

“…Highlights•PRES and RCVS may associate with postpartum pre-eclampsia and eclampsia. •PRES may require aggressive medical and surgical management. •Hemispheric…”
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Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma by Hottinger, A F, Ben Aissa, A, Espeli, V, Squiban, D, Dunkel, N, Vargas, M I, Hundsberger, T, Mach, N, Schaller, K, Weber, D C, Bodmer, A, Dietrich, P-Y

“…This corrects the article DOI: 10.1038/bjc.2014.209…”
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Extra central nervous system metastases from glioblastoma: a new possible trigger event? by Simonetti, G., Silvani, A., Fariselli, L., Hottinger, A. F., Pesce, G. A., Prada, F., Gaviani, P.

“…Extra-cranial metastases of glioblastoma (GBM) represent a rare event, and the biological-genetic mechanisms involved in the pathogenesis have not yet been…”
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Patterns of care in recurrent glioblastoma in Switzerland: a multicentre national approach based on diagnostic nodes by Hundsberger, T., Hottinger, A. F., Roelcke, U., Roth, P., Migliorini, D., Dietrich, P. Y., Conen, K., Pesce, G., Hermann, E., Pica, A., Gross, M. W., Brügge, D., Plasswilm, L., Weller, M., Putora, P. M.

“…Despite moderate improvements in outcome of glioblastoma after first-line treatment with chemoradiation recent clinical trials failed to improve the prognosis…”
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Decision making and management of gliomas: practical considerations by Hottinger, A F, Homicsko, K, Negretti, L, Lhermitte, B, Stupp, R

“…Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined…”
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Recent advances in the management of atypical meningiomas by Messerer, M, Richoz, B, Cossu, G, Dhermain, F, Hottinger, A.F, Parker, F, Levivier, M, Daniel, R.T

“…Abstract Based on the 2007 WHO classification, the proportion of atypical meningiomas has steeply increased. Complete resection is usually considered curative,…”
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Serum YKL-40 is a marker of prognosis and disease status in high-grade gliomas by Iwamoto, F. M., Hottinger, A. F., Karimi, S., Riedel, E., Dantis, J., Jahdi, M., Panageas, K. S., Lassman, A. B., Abrey, L. E., Fleisher, M., DeAngelis, L. M., Holland, E. C., Hormigo, A.

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Therapeutic strategies for the management of gliomas by Hottinger, A F, Stupp, R

“…The management of gliomas remains challenging and requires a multidisciplinary approach that involves neurosurgeons, radiation therapists and oncologists. For…”
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Extra central nervous system metastases from glioblastoma: a new possible trigger event? by Simonetti, G., Silvani, A., Fariselli, L., Hottinger, A. F., Pesce, G. A., Prada, F., Gaviani, P.

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Cellular xenotransplantation by Aebischer, Patrick, Hottinger, Andreas F, Déglon, Nicole

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New patterns of magnetic resonance images in high-grade glioma patients treated with bevacizumab (Avastin®) by Gariani, J, Hottinger, AF, Ben Aissa, A, Korchi, MA, Boto, Jose, Gariani, K, Lovblad, KO, Vargas, MI

“…Objectives: To identify new magnetic resonance imaging (MRI) patterns in patients with high-grade glioma treated with bevacizumab (Avastin®). Methods: The…”
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Amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam: quantitative neuropathology, immunohistochemical analysis of neuronal vulnerability, and comparison with related neurodegenerative disorders by Hof, P R, Nimchinsky, E A, Buée-Scherrer, V, Buée, L, Nasrallah, J, Hottinger, A F, Purohit, D P, Loerzel, A J, Steele, J C, Delacourte, A

“…Amyotrophic lateral sclerosis/parkinsonism-dementia complex (lytico-bodig) is a chronic neurodegenerative disorder with high prevalence among the native…”
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The Copper Chelator d-Penicillamine Delays Onset of Disease and Extends Survival in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis by Hottinger, Andreas F., Fine, Eric G., Gurney, Mark E., Zurn, Anne D., Aebischer, Patrick

“…A subpopulation of familial cases of amyotrophic lateral sclerosis has been linked to mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1). There…”
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P03.05 Supporting function of nurses to facilitate TTFields therapy for primary and recurrent Glioblastoma in clinical routine by Kilias, M, Pellet, C, Hottinger, A F

“…Abstract Introduction Tumor treating fields (TTFields, Optune®) are an approved novel GBM treatment modality with antimitotic efficacy. Optune delivers…”
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