Search Results - "Hotha, Kishore Kumar"

Determination of the quaternary ammonium compound trospium in human plasma by LC–MS/MS: Application to a pharmacokinetic study by Hotha, Kishore Kumar, Bharathi, D. Vijaya, Kumar, Sanagapati Sirish, Reddy, Y. Narasimha, Chatki, Pankaj K., Ravindranath, L.K., Jayaveera, K.N.

“…A highly sensitive, specific and evaporation free SPE extraction, LC–MS/MS method has been developed for the estimation of trospium in human plasma using…”
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Development and validation of a highly sensitive and robust LC–MS/MS with electrospray ionization method for simultaneous quantitation of itraconazole and hydroxyitraconazole in human plasma: Application to a bioequivalence study by Bharathi, D. Vijaya, Hotha, Kishore Kumar, Sagar, P.V.Vidya, Kumar, Sanagapati Sirish, Reddy, Pandu Ranga, Naidu, A., Mullangi, Ramesh

“…A highly sensitive and specific LC–MS/MS method has been developed for simultaneous estimation of itraconazole (ITZ) and hydroxyitraconazole (OH-ITZ) with 500…”
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Identification, Synthesis, and Characterization of Unknown Impurity in the Famotidine Powder for Oral Suspension Due to Excipient Interaction by UPLC-MS/MS and NMR by Hotha, Kishore Kumar, Patel, Tejashkumar, Roychowdhury, Swapan, Subramanian, Veerappan

“…Excipients interactions with the drug product are the most predominant causes for a product failure. Regulated guidelines have stringent limits for the unknown…”
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Rapid and sensitive LC-MS/MS method for quantification of lamotrigine in human plasma: application to a human pharmacokinetic study by Hotha, Kishore Kumar, Kumar, S.Sirish, Bharathi, D. Vijaya, Venkateswarulu, V.

“…ABSTRACT A highly sensitive, specific and fully validated LC‐MS/MS method as per general practices of industry has been developed for estimation of lamotrigine…”
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Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study by Vijaya Bharathi, D., Jagadeesh, B., Hotha, Kishore Kumar, Patil, Uday, Bhushan, Indu

“…A highly sensitive, selective and evaporation free SPE extraction, ESI-LC–MS/MS method has been developed for estimation of misoprostol free acid in human…”
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Rapid quantification of amlodipine enantiomers in human plasma by LC-MS/MS: application to a clinical pharmacokinetic study by Hotha, Kishore Kumar, Roychowdhury, Swapan, Mullangi, Ramesh, Ravindranath, L. K.

“…ABSTRACT A rapid, simple, specific and sensitive LC‐MS/MS method has been developed and validated for the enantiomeric quantification of amlodipine (AML)…”
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LC-MS/MS method for simultaneous estimation of candesartan and hydrochlorothiazide in human plasma and its use in clinical pharmacokinetics by Bharathi, D Vijaya, Hotha, Kishore Kumar, Chatki, Pankaj K, Satyanarayana, V, Venkateswarlu, V

“…ATACAND HCT(®) (candesartan cilexetil-hydrochlorothiazide [CAN-HCTZ]) combines an angiotensin II receptor (type AT1) antagonist and a diuretic. Quantification…”
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Sensitive method for the determination of paricalcitol by liquid chromatography and mass spectrometry and its application to a clinical pharmacokinetic study by Hotha, Kishore Kumar, Mullangi, Ramesh, Lakshmanarao Krishnarao, Ravindranath, Roychowdhury, Swapan

“…A highly sensitive, specific and rapid LC‐ESI‐MS/MS method has been developed and validated for the quantification of paricalcitol (PAR) in human plasma (500…”
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LC-MS/MS determination and pharmacokinetic study of lacidipine in human plasma by Chatki, Pankaj Kisan, Hotha, Kishore Kumar, Kolagatla, Pandu Ranga Reddy, Bharathi, D. Vijaya, Venkateswarulu, V.

“…ABSTRACT A robust, specific and fully validated LC‐MS/MS method as per general practices of industry has been developed for estimation of lacidipine (LAC) with…”
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Low dose aspirin estimation: an application to a human pharmacokinetic study by Vijaya Bharathi, D., Hotha, Kishore Kumar, Kolagatla, Pandu Ranga Reddy, Venkateswarlu, V.

“…ABSTRACT Low dose to very high dose aspirin is used to prevent heart attack. We have developed and validated a sensitive and robust method that could detect…”
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Complexity in estimation of esomeprazole and its related impurities' stability in various stress conditions in low-dose aspirin and esomeprazole magnesium capsules by Reddy, Palavai Sripal, Hotha, Kishore Kumar, Sait, Shakil

“…A complex, sensitive, and precise high-performance liquid chromatographic method for the profiling of impurities of esomeprazole in low-dose aspirin and…”
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Quantification of montelukast, a selective cysteinyl leukotriene receptor (CysLT1) antagonist in human plasma by liquid chromatography-mass spectrometry: validation and its application to a human pharmacokinetic study by Bharathi, D. Vijaya, Hotha, Kishore Kumar, Jagadeesh, B., Mullangi, Ramesh, Naidu, A.

“…A highly sensitive, rapid assay method has been developed and validated for the estimation of montelukast (MTK) in human plasma with liquid chromatography…”
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Simultaneous estimation of amlodipine and atenolol in human plasma: a sensitive LC-MS/MS method validation and its application to a clinical PK study by Kallem, Raja Reddy, Mullangi, Ramesh, Hotha, Kishore Kumar, Ravindranath, L K, Spoorthy, Y N, Seshagirirao, J V L N

“…A highly sensitive, specific and rapid LC-ESI-MS/MS method has been developed and validated for simultaneous quantification of amlodipine (AMD) and atenolol…”
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Simultaneous estimation of four proton pump inhibitors-lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study by Bharathi, D. Vijaya, Hotha, Kishore Kumar, Jagadeesh, B., Chatki, Pankaj K., Thriveni, K., Mullangi, Ramesh, Naidu, A.

“…A highly selective, sensitive and accurate HPLC method has been developed and validated for the estimation of four proton‐pump inhibitors (PPI), lansoprazole…”
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Development and validation of a highly sensitive LC-MS/MS method for quantitation of dexlansoprazole in human plasma: application to a human pharmacokinetic study by Hotha, Kishore Kumar, Vijaya Bharathi, D., Jagadeesh, B., Ravindranath, L. K., Jaya Veera, K. N., Venkateswarulu, V.

“…ABSTRACT A highly sensitive, specific and simple LC‐MS/MS method was developed for the simultaneous estimation of dexlansoprazole (DEX) with 50 μL of human…”
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Highly sensitive method for the determination of omeprazole in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study by Vittal, Shivva, Ganneboina, Ramesh, Layek, Buddhadev, Trivedi, Ravi Kumar, Hotha, Kishore Kumar, Bharathi, D. Vijaya, Mullangi, Ramesh

“…A highly sensitive, rapid assay method has been developed and validated for the estimation of omeprazole (OPZ) in human plasma with liquid chromatography…”
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Species difference in the in vitro and in vivo metabolism of amtolmetin guacil by Hotha, Kishore Kumar, Dasari, Vijaya Bharathi, Shaik, Abdul Naveed, Syed, Muzeeb, Shivva, Vittal, Lakshmanarao, Ravindranath Krishnarao, Korlakunta, Jayaveera Narasimhulu, Mullangi, Ramesh

“…Abstract Tolmetin (TMT, CAS 26171-23-3) is a non-steroidal anti-inflammatory drug (NSAID) indicated for the relief of signs and symptoms of osteoarthritis,…”
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Highly sensitive method for the determination of ropinirole with a lower limit of quantitation of 3.45 pg/mL in human plasma by LC-ESI-MS/MS: application to a clinical pharmacokinetic study by Bharathi, D. Vijaya, Jagadeesh, B., Kumar, S. Sirish, Lakshmi, Revathi Naga, Hotha, Kishore Kumar, Naidu, A., Mullangi, Ramesh

“…A highly sensitive, rapid assay method has been developed and validated for the estimation of ropinirole (RPR) in human plasma with liquid chromatography…”
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A rapid LC-MS/MS method for quantitation of eszopiclone in human plasma: application to a human pharmacokinetic study by Hotha, Kishore Kumar, Vijaya Bharathi, D., Jagadeesh, B., Ravindranath, L. K., Jaya Veera, K. N., Venkateswarulu, V.

“…ABSTRACT A highly reproducible, specific and cost‐effective LC‐MS/MS method was developed for simultaneous estimation of eszopiclone (ESZ) with 50 μL of human…”
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Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study by Bharathi, D. Vijaya, Hotha, Kishore Kumar, Sagar, P. V. Vidya, Kumar, S. Sirish, Naidu, A., Mullangi, Ramesh

“…A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of pramipexole (PPX) with 500 µL human plasma using…”
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