Search Results - "Hota, Swetansu K."

ATP-dependent chromatin remodeling during mammalian development by Hota, Swetansu K, Bruneau, Benoit G

“…Precise gene expression ensures proper stem and progenitor cell differentiation, lineage commitment and organogenesis during mammalian development…”
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ISWI Remodelers Slide Nucleosomes with Coordinated Multi-Base-Pair Entry Steps and Single-Base-Pair Exit Steps by Deindl, Sebastian, Hwang, William L., Hota, Swetansu K., Blosser, Timothy R., Prasad, Punit, Bartholomew, Blaine, Zhuang, Xiaowei

“…ISWI-family enzymes remodel chromatin by sliding nucleosomes along DNA, but the nucleosome translocation mechanism remains unclear. Here we use single-molecule…”
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Brg1 modulates enhancer activation in mesoderm lineage commitment by Alexander, Jeffrey M, Hota, Swetansu K, He, Daniel, Thomas, Sean, Ho, Lena, Pennacchio, Len A, Bruneau, Benoit G

“…The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histone modifications and chromatin…”
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Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis by Hota, Swetansu K, Johnson, Jeffrey R, Verschueren, Erik, Thomas, Reuben, Blotnick, Aaron M, Zhu, Yiwen, Sun, Xin, Pennacchio, Len A, Krogan, Nevan J, Bruneau, Benoit G

“…Chromatin remodeling complexes instruct cellular differentiation and lineage specific transcription. The BRG1/BRM associated factor (BAF) complexes are…”
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Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation by Bhardwaj, Saurabh K., Hailu, Solomon G., Olufemi, Lola, Brahma, Sandipan, Kundu, Soumyadipta, Hota, Swetansu K., Persinger, Jim, Bartholomew, Blaine

“…Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order…”
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Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling by Hada, Arjan, Hota, Swetansu K., Luo, Jie, Lin, Yuan-chi, Kale, Seyit, Shaytan, Alexey K., Bhardwaj, Saurabh K., Persinger, Jim, Ranish, Jeff, Panchenko, Anna R., Bartholomew, Blaine

“…Nucleosomes are the fundamental building blocks of chromatin that regulate DNA access and are composed of histone octamers. ATP-dependent chromatin remodelers…”
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Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function by Sun, Xin, Hota, Swetansu K, Zhou, Yu-Qing, Novak, Stefanie, Miguel-Perez, Dario, Christodoulou, Danos, Seidman, Christine E, Seidman, J G, Gregorio, Carol C, Henkelman, R Mark, Rossant, Janet, Bruneau, Benoit G

“…How chromatin-remodeling complexes modulate gene networks to control organ-specific properties is not well understood. For example, ( ) encodes a…”
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Diversity of operation in ATP-dependent chromatin remodelers by Hota, Swetansu K., Bartholomew, Blaine

“…Chromatin is actively restructured by a group of proteins that belong to the family of ATP-dependent DNA translocases. These chromatin remodelers can assemble,…”
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Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease by Kathiriya, Irfan S., Rao, Kavitha S., Iacono, Giovanni, Devine, W. Patrick, Blair, Andrew P., Hota, Swetansu K., Lai, Michael H., Garay, Bayardo I., Thomas, Reuben, Gong, Henry Z., Wasson, Lauren K., Goyal, Piyush, Sukonnik, Tatyana, Hu, Kevin M., Akgun, Gunes A., Bernard, Laure D., Akerberg, Brynn N., Gu, Fei, Li, Kai, Speir, Matthew L., Haeussler, Maximilian, Pu, William T., Stuart, Joshua M., Seidman, Christine E., Seidman, J.G., Heyn, Holger, Bruneau, Benoit G.

“…Haploinsufficiency of transcriptional regulators causes human congenital heart disease (CHD); however, the underlying CHD gene regulatory network (GRN)…”
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Brahma safeguards canalization of cardiac mesoderm differentiation by Hota, Swetansu K., Rao, Kavitha S., Blair, Andrew P., Khalilimeybodi, Ali, Hu, Kevin M., Thomas, Reuben, So, Kevin, Kameswaran, Vasumathi, Xu, Jiewei, Polacco, Benjamin J., Desai, Ravi V., Chatterjee, Nilanjana, Hsu, Austin, Muncie, Jonathon M., Blotnick, Aaron M., Winchester, Sarah A. B., Weinberger, Leor S., Hüttenhain, Ruth, Kathiriya, Irfan S., Krogan, Nevan J., Saucerman, Jeffrey J., Bruneau, Benoit G.

“…Differentiation proceeds along a continuum of increasingly fate-restricted intermediates, referred to as canalization 1 , 2 . Canalization is essential for…”
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Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains by Hota, Swetansu K, Bhardwaj, Saurabh K, Deindl, Sebastian, Lin, Yuan-chi, Zhuang, Xiaowei, Bartholomew, Blaine

“…The ISWI chromatin remodelers interact with extranucleosomal DNA to mediate nucleosome positioning. A new study now shows that the conserved SLIDE domain in…”
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Disparity in the DNA translocase domains of SWI/SNF and ISW2 by Dechassa, Mekonnen Lemma, Hota, Swetansu K, Sen, Payel, Chatterjee, Nilanjana, Prasad, Punit, Bartholomew, Blaine

“…An ATP-dependent DNA translocase domain consisting of seven conserved motifs is a general feature of all ATP-dependent chromatin remodelers. While motifs on…”
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An assay for exogenous sources of purified MurG, enabled by the complementation of Escherichia coli murG(Ts) by the Mycobacterium tuberculosis homologue by Jha, Ramesh K., Katagihallimath, Nainesh, Hota, Swetansu K., Das, Kaveri S., de Sousa, Sunita M.

“…Abstract The Mycobacterium tuberculosis murG gene, Rv2153, was expressed in Escherichia colimurG(Ts) strain OV58 on a plasmid under the control of the…”
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Approaches for studying nucleosome movement by ATP-dependent chromatin remodeling complexes by Hota, Swetansu K, Bartholomew, Blaine

“…Packaging DNA into compact chromatin enables eukaryotic cells to organize and regulate their genome. Packaging is achieved by wrapping ∼146-147 bp of DNA…”
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Mapping protein-DNA and protein-protein interactions of ATP-dependent chromatin remodelers by Hota, Swetansu K, Dechassa, Mekonnen Lemma, Prasad, Punit, Bartholomew, Blaine

“…Chromatin plays a key regulatory role in several DNA-dependent processes as it regulates DNA access to different protein factors. Several multisubunit protein…”
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The structure and function of ATP‐dependent chromatin remodeling complexes by Bartholomew, Blaine, Dechassa, Mekonnen Lemma, Hota, Swetansu K, Prasad, Punit, Sen, Payel, Gosh, Sujana, Hemeryck, Christine S., Pugh, Frank, Pondugula, Santhi, Kladde, Michael P.

“…ATP‐dependent chromatin remodelers are key regulators of the epigenome and have important roles in transcription, replication, repair and recombination of DNA…”
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Immobilization of tannase from Rhizopus oryzae and its efficiency to produce gallic acid from tannin rich agro-residues by Hota, S K, Dutta, J R, Banerjee, R

“…Different tannin rich agro-residues, like sal seed (21% tannin), fruit of myrobalan (37.6% tannin) and tea-leaf (14.1% tannin) were selected for enzymatic…”
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