Search Results - "Hota, Charulata"

Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways by TUCK, Alan B, HOTA, Charulata, WILSON, Sylvia M, CHAMBERS, Ann F

“…Osteopontin (OPN) is a secreted, integrin-binding glycophosphoprotein that has been implicated in breast cancer. We previously showed that OPN-induced cell…”
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Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells by TUCK, A. B, ARSENAULT, D. M, O'MALLEY, F. P, HOTA, C, LING, M. C, WILSON, S. M, CHAMBERS, A. F

“…Osteopontin (OPN) has been associated with enhanced malignancy in breast cancer, but its functional role in this disease is poorly understood. To study the…”
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Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met) by Tuck, Alan B., Elliott, Bruce E., Hota, Charulata, Tremblay, Eric, Chambers, Ann F.

“…Osteopontin (OPN) is a secreted glycophosphoprotein which induces migration of mammary carcinoma cells, and has been implicated in the malignancy of breast…”
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Osteopontin(OPN)-induced increase in human mammary epithelial cell invasiveness is urokinase (uPA)-dependent by TUCK, Alan B, HOTA, Charulata, CHAMBERS, Ann F

“…We have recently shown that either exogenous or endogenous, transfected OPN induces both uPA expression and increased invasiveness of 21 PT (non-tumorigenic)…”
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Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions by Xuan, J W, Hota, C, Shigeyama, Y, D'Errico, J A, Somerman, M J, Chambers, A F

“…Osteopontin (OPN) is a secreted calcium-binding phosphoprotein produced in a variety of normal and pathological contexts, including tissue mineralization and…”
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Recombinant GST-human osteopontin fusion protein is functional in RGD-dependent cell adhesion by Xuan, J W, Hota, C, Chambers, A F

“…Osteopontin (OPN) is a secreted phosphoprotein expressed by many tumor cells, as well as a limited set of normal cells. Native OPN has been shown to support…”
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β3 Integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin by FURGER, Kara A, ALLAN, Alison L, WILSON, Sylvia M, HOTA, Charulata, VANTYGHEM, Sharon A, POSTENKA, Carl O, AL-KATIB, Waleed, CHAMBERS, Ann F, TUCK, Alan B

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Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin by Furger, Kara A, Allan, Alison L, Wilson, Sylvia M, Hota, Charulata, Vantyghem, Sharon A, Postenka, Carl O, Al-Katib, Waleed, Chambers, Ann F, Tuck, Alan B

“…Osteopontin (OPN) is a secreted phosphoprotein that has been associated with malignancy of breast and other cancers. OPN binds to several cell surface…”
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β3 Integrin Expression Increases Breast Carcinoma Cell Responsiveness to the Malignancy-Enhancing Effects of Osteopontin11Grant 12078 from the Canadian Breast Cancer Research Initiative (A.F.C. and A.B.T.) A.L.A. is supported by the H.L. Holmes Postdoctoral Award from the National Research Council of Canada. S.A.V. is supported by a predoctoral award from the U.S. Medical Research and Material Command Breast Cancer Research Program. This work was performed in partial fulfillment of the requirem by Kara A. Furger, Alison L. Allan, Sylvia M. Wilson, Charulata Hota, Sharon A. Vantyghem, Carl O. Postenka, Waleed Al-Katib, Ann F. Chambers, Alan B. Tuck

“…Osteopontin (OPN) is a secreted phosphoprotein that has been associated with malignancy of breast and other cancers. OPN binds to several cell surface…”
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Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin by Bautista, D S, Xuan, J W, Hota, C, Chambers, A F, Harris, J F

“…Osteopontin (OPN), a secreted phosphoprotein, has been implicated in various biological phenomena (e.g. bone development, sepsis, tumor progression, and…”
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Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin by CHAMBERS, A. F, HOTA, C, PRINCE, C. W

“…We previously reported that H-ras-induced metastatic ability in murine NIH 3T3 cells is accompanied by increased expression of osteopontin (OPN). OPN is a…”
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