Search Results - "Hostettler, Lu"

Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia by Huang, Xiao, Anderle, Pascale, Hostettler, Lu, Baumann, Marc U, Surbek, Daniel V, Ontsouka, Edgar C, Albrecht, Christiane

“…Gestational disorders such as intrauterine growth restriction (IUGR) and pre-eclampsia (PE) are main causes of poor perinatal outcomes worldwide. Both diseases…”
Get full text

Examining Uncertainty in In Vitro–In Vivo Extrapolation Applied in Fish Bioconcentration Models by Laue, Heike, Hostettler, Lu, Badertscher, Remo P, Jenner, Karen J, Sanders, Gordon, Arnot, Jon A, Natsch, Andreas

“…In vitro biotransformation rates were determined for 30 chemicals, mostly fragrance ingredients, using trout liver S9 fractions (RT-S9) and incorporated into…”
Get full text

A critical assessment of the estrogenic potency of benzyl salicylate by Natsch, Andreas, Hostettler, Lu, Haupt, Tina, Laue, Heike

“…•Benzyl salicylate (BS) is on priority lists for evaluation of estrogenic effects.•New data in both MCF7 (E-screen) and luciferase transactivation…”
Get full text

Benzoyl-CoA conjugate accumulation as an initiating event for male reprotoxic effects in the rat? Structure–activity analysis, species specificity, and in vivo relevance by Laue, Heike, Badertscher, Remo P., Hostettler, Lu, Weiner-Sekiya, Yumiko, Haupt, Tina, Nordone, Adrian, Adamson, Gregory M., Natsch, Andreas

“…A number of para -substituted benzoic acids ( p -BA) and chemicals metabolized to p -BA have been found to confer adverse effects in male rats on sperm…”
Get full text

Bioconcentration Assessment in Fish Based on In Vitro Intrinsic Clearance: Predictivity of an Empirical Model Compared to In Vitro–In Vivo Extrapolation Models by Laue, Heike, Hostettler, Lu, Jenner, Karen J., Sanders, Gordon, Natsch, Andreas

“…To estimate the bioconcentration factor (BCF), the in vitro intrinsic clearance (CLIN VITRO,INT) from rainbow trout liver S9 fractions (RT-S9) can be applied…”
Get full text

PeBiToSens™: A Platform for PBT Screening of Fragrance Ingredients Without Animal Testing by Laue, Heike, Hostettler, Lu, Sanders, Gordon, Kreutzer, Georg, Natsch, Andreas

“…The determination of persistence (P), bioaccumulation (B) and toxicity (T) plays a central role in the environmental assessment of chemicals. Persistence is…”
Get full text

Impaired placental thiamine transport in human pregnancy diseases by Huang, Xiao, Hostettler, Lu, Lüthi, Michael, Baumann, Marc, Surbek, Daniel, Ontsouka, Edgar, Albrecht, Christiane

Get full text

Identification of important placental nutrient transporters in intrauterine growth restriction and preeclampsia using various strategies by Huang, Xiao, Anderle, Pascale, Hostettler, Lu, Lüthi, Michael, Baumann, Marc, Surbek, Daniel, Ontsouka, Edgar, Albrecht, Christiane

Get full text