Search Results - "Hosszu, Adam"

RAAS inhibitors directly reduce diabetes‐induced renal fibrosis via growth factor inhibition by Koszegi, Sandor, Molnar, Agnes, Lenart, Lilla, Hodrea, Judit, Balogh, Dora Bianka, Lakat, Tamas, Szkibinszkij, Edgar, Hosszu, Adam, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Key points Increased activation of the renin‐angiotensin‐aldosterone system (RAAS) and elevated growth factor production are of crucial importance in the…”
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Lyophilization and homogenization of biological samples improves reproducibility and reduces standard deviation in molecular biology techniques by Molnar, Agnes, Lakat, Tamas, Hosszu, Adam, Szebeni, Beata, Balogh, Anna, Orfi, Laszlo, Szabo, Attila J., Fekete, Andrea, Hodrea, Judit

“…Lyophilization is a cost-effective method for biological specimen preservation but detailed tissue-specific reference protocols are still lacking. Moreover,…”
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The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants by Hosszu, Adam, Toth, Akos R, Lakat, Tamas, Stepanova, Ganna, Antal, Zsuzsanna, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea

“…Kidney transplantation is the preferred treatment for patients with end-stage kidney disease. Maintaining organ viability between donation and transplantation,…”
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The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats by Lenart, Lilla, Hodrea, Judit, Hosszu, Adam, Koszegi, Sandor, Zelena, Dora, Balogh, Dora, Szkibinszkij, Edgar, Veres-Szekely, Apor, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J., Fekete, Andrea

“…Rationale Depression is highly prevalent in diabetes (DM). Brain-derived neurotrophic factor (BDNF) which is mainly regulated by the endoplasmic reticulum…”
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Animal Models of Renal Pathophysiology and Disease by Hosszu, Adam, Kaucsar, Tamas, Seeliger, Erdmann, Fekete, Andrea

“…Renal diseases remain devastating illnesses with unacceptably high rates of mortality and morbidity worldwide. Animal models are essential tools to better…”
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Evaluation of a child with suspected nephrolithiasis by Reusz, George S., Hosszu, Adam, Kis, Eva

“…As the incidence of nephrolithiasis in children doubles every 10 years it is becoming a common disease associated with significant morbidity along with…”
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MO1019: Sigma-1 Receptor Agonists are Protective in a Rat Model of Kidney Transplantation by Lakat, Tamas, Roland Toth, Akos, Hodrea, Judit, Wagner, Laszlo, Szabo, Attila, Fekete, Andrea, Hosszu, Adam

“…Abstract BACKGROUND AND AIMS End-stage renal disease affects nearly 2 million people worldwide. The disease is associated with an irreversible deterioration in…”
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10-LB: Activation of Sigma-1 Receptor as a Novel Therapeutic Target in Diabetic Kidney Disease by BALOGH, DORA B., LENART, LILLA, HOSSZU, ADAM, SAEED, ADAR, HODREA, JUDIT, TOTH, AKOS R., SZABO, ATTILA J., FEKETE, ANDREA

“…Introduction and aims: Diabetic kidney disease (DKD) is a major health concern among diabetic patients. Current therapies cannot halt the progression of renal…”
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MO282: Sigma-1 Receptor Agonists are Protective in Renal Ischemia/Reperfusion Injury by Roland Toth, Akos, Lakat, Tamas, Hodrea, Judit, Balogh, Dora B, Vannay, Adam, Wagner, Laszlo, Szabo, Attila, Fekete, Andrea, Hosszu, Adam

“…Abstract BACKGROUND AND AIMS Renal ischemia/reperfusion injury (IRI)-induced acute kidney injury is associated with high mortality and morbidity and effective…”
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Preparation and Monitoring of Small Animals in Renal MRI by Kaucsar, Tamas, Hosszu, Adam, Seeliger, Erdmann, Reimann, Henning M, Fekete, Andrea

“…Renal diseases remain devastating illnesses with unacceptably high rates of mortality and morbidity worldwide. Animal models are essential tools to better…”
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Reduced O -GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney by Hodrea, Judit, Balogh, Dora B, Hosszu, Adam, Lenart, Lilla, Besztercei, Balazs, Koszegi, Sandor, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea

“…Diabetic kidney disease is a worldwide epidemic, and therapies are incomplete. Clinical data suggest that improved renal outcomes by Na -glucose cotransporter…”
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Reversible (Patho)Physiologically Relevant Test Interventions: Rationale and Examples by Cantow, Kathleen, Ladwig-Wiegard, Mechthild, Flemming, Bert, Fekete, Andrea, Hosszu, Adam, Seeliger, Erdmann

“…Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of acute kidney injury of various origins, and may also promote…”
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Perinatal asphyxia leads to acute kidney damage and increased renal susceptibility in adulthood by Lakat, Tamas, Fekete, Andrea, Demeter, Kornel, Toth, Akos R, Varga, Zoltan K, Patonai, Attila, Kelemen, Hanga, Budai, Andras, Szabo, Miklos, Szabo, Attila J, Kaila, Kai, Denes, Adam, Mikics, Eva, Hosszu, Adam

“…Perinatal asphyxia (PA) poses a significant threat to multiple organs, particularly the kidneys. Diagnosing PA-associated kidney injury remains challenging,…”
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MO620ANTIFIBROTIC EFFECTS OF SGLT2 INHIBITION IN THE KIDNEY AND PROXIMAL TUBULAR CELLS by Balogh, Dora, Hodrea, Judit, Hosszu, Adam, Lakat, Tamas, Saeed, Adar, Lenart, Lilla, Wagner, Laszlo, Szabo, Attila, Fekete, Andrea

“…Abstract Background and Aims Diabetic kidney disease (DKD) is a major cause of chronic kidney disease and end stage renal disease, therefore identification of…”
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Antidepressant effect in diabetes-associated depression: A novel potential of RAAS inhibition by Balogh, Dora B., Molnar, Agnes, Hosszu, Adam, Lakat, Tamas, Hodrea, Judit, Szabo, Attila J., Lenart, Lilla, Fekete, Andrea

“…Summary of the antidepressant-like mechanism of RAAS-acting drugs. Systemic and local brain renin-angiotensin-aldosterone system (RAAS) are overactivated in…”
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σ1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury by Hosszu, Adam, Antal, Zsuzsanna, Lenart, Lilla, Hodrea, Judit, Koszegi, Sandor, Balogh, Dora B, Banki, Nora F, Wagner, Laszlo, Denes, Adam, Hamar, Peter, Degrell, Peter, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Mechanisms of renal ischemia-reperfusion injury remain unresolved, and effective therapies are lacking. We previously showed that dehydroepiandrosterone…”
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P1669PROGNOSTIC IMPORTANCE OF BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) IN RENAL TRANSPLANTATION by Molnar, Agnes, Szkibinszkij, Edgar, Lenart, Lilla, Hosszu, Adam, Kovacs, Illes, Wagner, Laszlo, Rimaszombati, Fruzsina, Novozanszki, Soma, Szabo, Attila, Fekete, Andrea

“…Abstract Background and Aims The prevalence of end-stage renal disease (ESRD) has increased ten times higher in the past twenty years, where renal replacement…”
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Novel therapeutic potential of angiotensin receptor 1 blockade in a rat model of diabetes-associated depression parallels altered BDNF signalling by Lenart, Lilla, Balogh, Dora B., Lenart, Nikolett, Barczi, Adrienn, Hosszu, Adam, Farkas, Tamas, Hodrea, Judit, Szabo, Attila J., Szigeti, Krisztian, Denes, Adam, Fekete, Andrea

“…Aims/hypothesis Diabetes is a worldwide epidemic linked with diverse diseases of the nervous system, including depression. A few studies suggested a connection…”
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MO1016MULTIPLE-ORGAN DAMAGE FOLLOWING PERINATAL ASPHYXIA IN RAT MODEL by Lakat, Tamas, Hosszu, Adam, Molnar, Agnes, Toth, Akos Roland, Demeter, Kornel, Kelemen, Hanga, Szabo, Attila, Denes, Adam, Szabó, Miklós, Mikics, Eva, Fekete, Andrea

“…Abstract Background and Aims Perinatal asphyxia (PA) is associated with more than half a million mature newborn deaths yearly. It may lead to severe…”
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Role of O-linked N-acetylglucosamine modification in diabetic nephropathy by Gellai, Renata, Hodrea, Judit, Lenart, Lilla, Hosszu, Adam, Koszegi, Sandor, Balogh, Dora, Ver, Agota, Banki, Nora F, Fulop, Norbert, Molnar, Agnes, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Increased O-linked β-N-acetylglucosamine glycosylation (O-GlcNAcylation) is a known contributor to diabetes; however, its relevance in diabetic nephropathy…”
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