Search Results - "Hossjer, Ola"
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Do estimates of contemporary effective population size tell us what we want to know?
Published in Molecular ecology (01-04-2019)“…Estimation of effective population size (Ne) from genetic marker data is a major focus for biodiversity conservation because it is essential to know at what…”
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Using statistical methods to model the fine-tuning of molecular machines and systems
Published in Journal of theoretical biology (21-09-2020)“…[Display omitted] •Statistical methods are appropriate for modelling fine-tuning.•Fine-tuning is detected in functional proteins, cellular networks…”
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3
Use of directed quasi-metric distances for quantifying the information of gene families
Published in BioSystems (01-09-2024)“…A large hindrance to analyzing information in genetic or protein sequence data has been a lack of a mathematical framework for doing so. In this paper, we…”
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Estimating the information content of genetic sequence data
Published in Journal of the Royal Statistical Society Series C: Applied Statistics (22-12-2023)“…Abstract A prominent problem in analysing genetic information has been a lack of mathematical frameworks for doing so. This article offers some new statistical…”
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Variance effective population size is affected by census size in sub‐structured populations
Published in Molecular ecology resources (01-08-2023)“…Measurement of allele frequency shifts between temporally spaced samples has long been used for assessment of effective population size (Ne), and this…”
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A spatio-temporal point process model for particle growth
Published in Journal of applied probability (01-03-2019)“…A spatio-temporal model of particle or star growth is defined, whereby new unit masses arrive sequentially in discrete time. These unit masses are referred to…”
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Effects of subpopulation extinction on effective size (Ne) of metapopulations
Published in Conservation genetics (01-08-2023)“…Population extinction is ubiquitous in all taxa. Such extirpations can reduce intraspecific diversity, but the extent to which genetic diversity of surviving…”
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On the eigenvalue effective size of structured populations
Published in Journal of mathematical biology (01-09-2015)“…A general theory is developed for the eigenvalue effective size ( N e E ) of structured populations in which a gene with two alleles segregates in discrete…”
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On the waiting time until coordinated mutations get fixed in regulatory sequences
Published in Journal of theoretical biology (07-09-2021)“…•We study the waiting time until a number of coordinated mutations appear and change the expression of m genes in a population.•These mutations generate…”
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10
The representation, quantification, and nature of genetic information
Published in Synthese (Dordrecht) (27-06-2024)“…Current genetics studies often refer to notions from information science. The purpose of this paper is to summarize and structure the different notions of…”
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Classification Under Partial Reject Options
Published in Journal of classification (2024)“…In many applications there is ambiguity about which (if any) of a finite number N of hypotheses that best fits an observation. It is of interest then to…”
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What does effective population size tell us about loss of allelic variation?
Published in Evolutionary applications (01-06-2024)“…There are two primary measures of the amount of genetic variation in a population at a locus: heterozygosity and the number of alleles. Effective population…”
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On the use of L-functionals in regression models
Published in Open mathematics (Warsaw, Poland) (22-08-2023)“…In this article, we survey and unify a large class or -functionals of the conditional distribution of the response variable in regression models. This includes…”
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Assessment of the Global Variance Effective Size of Subdivided Populations, and Its Relation to Other Effective Sizes
Published in Acta biotheoretica (2023)“…The variance effective population size ( N eV ) is frequently used to quantify the expected rate at which a population’s allele frequencies change over time…”
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An Information Theoretic Approach to Prevalence Estimation and Missing Data
Published in IEEE transactions on information theory (01-05-2024)“…Many data sources, including tracking social behavior to election polling to testing studies for understanding disease spread, are subject to sampling bias…”
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Local fluctuations of genetic processes defined on two time scales, with applications to effective size estimation
Published in Theoretical population biology (01-02-2020)“…In this paper we develop a general framework for how the genetic composition of a structured population with strong migration between its subunits, evolves…”
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Assessing, Testing and Estimating the Amount of Fine-Tuning by Means of Active Information
Published in Entropy (Basel, Switzerland) (21-09-2022)“…A general framework is introduced to estimate how much external information has been infused into a search algorithm, the so-called active information. This is…”
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18
Sometimes Size Does Not Matter
Published in Foundations of physics (01-02-2023)“…Recently Díaz, Hössjer and Marks (DHM) presented a Bayesian framework to measure cosmological tuning (either fine or coarse) that uses maximum entropy (maxent)…”
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Sharp lower and upper bounds for the covariance of bounded random variables
Published in Statistics & probability letters (01-03-2022)“…In this paper we derive sharp lower and upper bounds for the covariance of two bounded random variables which are applicable when knowledge about their…”
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gesp: A computer program for modelling genetic effective population size, inbreeding and divergence in substructured populations
Published in Molecular ecology resources (01-11-2017)“…The genetically effective population size (Ne) is of key importance for quantifying rates of inbreeding and genetic drift and is often used in conservation…”
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