Search Results - "Hossain, Shaolie S."
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Review of Patient-Specific Vascular Modeling: Template-Based Isogeometric Framework and the Case for CAD
Published in Archives of computational methods in engineering (15-04-2019)“…We review the literature on patient-specific vascular modeling, with particular attention paid to three-dimensional arterial networks. Patient-specific…”
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Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke
Published in Frontiers in physiology (28-02-2022)“…Moyamoya disease (MMD) is a progressive steno-occlusive cerebrovascular disease leading to recurrent stroke. There is a lack of reliable biomarkers to identify…”
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USNCTAM perspectives on mechanics in medicine
Published in Journal of the Royal Society interface (06-08-2014)“…Over decades, the theoretical and applied mechanics community has developed sophisticated approaches for analysing the behaviour of complex engineering…”
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Reassessing the Role of Intra-Arterial Drug Delivery for Glioblastoma Multiforme Treatment
Published in Journal of Drug Delivery (01-01-2015)“…Effective treatment for glioblastoma (GBM) will likely require targeted delivery of several specific pharmacological agents simultaneously. Intra-arterial (IA)…”
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A parametric study of the effect of 3D plaque shape on local hemodynamics and implications for plaque instability
Published in Biomechanics and modeling in mechanobiology (01-08-2024)“…The vast majority of heart attacks occur when vulnerable plaques rupture, releasing their lipid content into the blood stream leading to thrombus formation and…”
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Image-guided subject-specific modeling of glymphatic transport and amyloid deposition
Published in Computer methods in applied mechanics and engineering (15-12-2023)“…The glymphatic system is a brain-wide system of perivascular networks that facilitate exchange of cerebrospinal fluid (CSF) and interstitial fluid (ISF) to…”
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A novel method for improving the accuracy of MR-derived patient-specific vascular models using X-ray angiography
Published in Engineering with computers (01-10-2022)“…MR imaging, a noninvasive radiation-free imaging modality commonly used during clinical follow-up, has been widely utilized to reconstruct realistic 3D…”
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In silico vascular modeling for personalized nanoparticle delivery
Published in Nanomedicine (London, England) (01-03-2013)“…To predict the deposition of nanoparticles in a patient-specific arterial tree as a function of the vascular architecture, flow conditions, receptor surface…”
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Mathematical modeling of coupled drug and drug-encapsulated nanoparticle transport in patient-specific coronary artery walls
Published in Computational mechanics (01-02-2012)“…The majority of heart attacks occur when there is a sudden rupture of atherosclerotic plaque, exposing prothrombotic emboli to coronary blood flow, forming…”
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Image-based patient-specific flow simulations are consistent with stroke in pediatric cerebrovascular disease
Published in Biomechanics and modeling in mechanobiology (01-12-2021)“…Moyamoya disease (MMD) is characterized by narrowing of the distal internal carotid artery and the circle of Willis (CoW) and leads to recurring ischemic and…”
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Vascular deposition patterns for nanoparticles in an inflamed patient-specific arterial tree
Published in Biomechanics and modeling in mechanobiology (01-06-2014)“…Inflammation, a precursor to many diseases including cancer and atherosclerosis, induces differential surface expression of specific vascular molecules…”
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Magnetic resonance imaging-based computational modelling of blood flow and nanomedicine deposition in patients with peripheral arterial disease
Published in Journal of the Royal Society interface (06-05-2015)“…Peripheral arterial disease (PAD) is generally attributed to the progressive vascular accumulation of lipoproteins and circulating monocytes in the vessel…”
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Flow arrest intra-arterial delivery of small TAT-decorated and neutral micelles to gliomas
Published in Journal of neuro-oncology (01-05-2017)“…The cell-penetrating trans-activator of transcription (TAT) is a cationic peptide derived from human immunodeficiency virus-1. It has been used to facilitate…”
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Liposome size and charge optimization for intraarterial delivery to gliomas
Published in Drug delivery and translational research (01-06-2016)“…Nanoparticles such as liposomes may be used as drug delivery vehicles for brain tumor therapy. Particle geometry and electrostatic properties have been…”
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Abstract 10101: Patient-specific Analysis Predicts Preferential Accumulation of VCAM-1 Targeted Nanoparticles Near Atherosclerotic Plaque
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionDetection and treatment of vulnerable plaques, the ones prone to rupture and cause heart attacks, remain a huge unmet clinical need. Inflammation…”
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Abstract 9841: Image-based Patient-specific Analysis Could Accurately Predict Stroke Events in Pediatric Cerebrovascular Disease
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionPediatric MoyaMoya Disease (MMD) is characterized by progressive narrowing of the major arteries in the circle of Willis (CoW) and rampant…”
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