Search Results - "Hospers, Geke A.P."

Preoperative chemoradiotherapy in locally advanced gastric cancer, a phase I/II feasibility and efficacy study by Trip, Anouk K, Poppema, Boelo J, van Berge Henegouwen, Mark I, Siemerink, Ester, Beukema, Jannet C, Verheij, Marcel, Plukker, John T.M, Richel, Dick J, Hulshof, Maarten C.C.M, van Sandick, Johanna W, Cats, Annemieke, Jansen, Edwin P.M, Hospers, Geke A.P

“…Abstract Objectives This study was initiated to investigate the feasibility and efficacy of preoperative radiotherapy with weekly paclitaxel and carboplatin in…”
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Disparities in survival of stomach cancer among different socioeconomic groups in North-East Netherlands by Siemerink, Ester J.M, Hospers, Geke A.P, Mulder, Nanno H, Siesling, Sabine, van der Aa, Maaike A

“…Abstract Background : Survival differences in stomach cancer are depended on patient, tumour and treatment factors. Some populations are more prone to develop…”
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Consideration of breast cancer subtype in targeting the androgen receptor by Venema, Clasina M., Bense, Rico D., Steenbruggen, Tessa G., Nienhuis, Hilde H., Qiu, Si-Qi, van Kruchten, Michel, Brown, Myles, Tamimi, Rulla M., Hospers, Geke A.P., Schröder, Carolina P., Fehrmann, Rudolf S.N., de Vries, Elisabeth G.E.

“…The androgen receptor (AR) is a drug target in breast cancer, and AR-targeted therapies have induced tumor responses in breast cancer patients. In this review,…”
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Quality of life and late toxicity after short-course radiotherapy followed by chemotherapy or chemoradiotherapy for locally advanced rectal cancer – The RAPIDO trial by Dijkstra, Esmée A., Hospers, Geke A.P., Kranenbarg, Elma Meershoek-Klein, Fleer, Joke, Roodvoets, Annet G.H., Bahadoer, Renu R., Guren, Marianne G., Tjalma, Jolien J.J., Putter, Hein, Crolla, Rogier M.P.H., Hendriks, Mathijs P., Capdevila, Jaume, Radu, Calin, van de Velde, Cornelis J.H., Nilsson, Per J., Glimelius, Bengt, van Etten, Boudewijn, Marijnen, Corrie A.M.

“…•No difference in QLQ-C30, QLQ-CR29 and LARS results between the EXP and STD group.•Sensory related symptoms more often in the EXP group compared to the STD…”
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Towards sustained silencing of HER2/neu in cancer by epigenetic editing by Falahi, Fahimeh, Huisman, Christian, Kazemier, Hinke G, van der Vlies, Pieter, Kok, Klaas, Hospers, Geke A P, Rots, Marianne G

“…The human epidermal growth factor receptor-2 (HER2/neu/ERBB2) is overexpressed in several cancer types. Although therapies targeting the HER2/neu protein…”
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Tumor immune microenvironmental characteristics in Human Epidermal Growth Factor-2 (HER2) positive esophageal adenocarcinoma: A comparative analysis and biomarker study by Stroes, Charlotte I., Meijer, Sybren L., Creemers, Geert-Jan, Hooijer, Gerrit K.J., Mohammad, Nadia Haj, Los, Maartje, Slingerland, Marije, Hospers, Geke A.P., Cats, Annemieke, Beerepoot, Laurens V., Bijlsma, Maarten F., van Laarhoven, Hanneke W.M.

“…•HER2 expression was associated with epithelial markers, which have been associated with favorable outcomes.•HER2 expression was associated with lower…”
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VEGF-PET Imaging Is a Noninvasive Biomarker Showing Differential Changes in the Tumor during Sunitinib Treatment by NAGENGAST, Wouter B, LUB-DE HOOGE, Marjolijn N, ELSINGA, Philip H, HESSELINK, Jan Willem, GIETEMA, Jourik A, DE VRIES, Elisabeth G. E, OOSTING, Sjoukje F, DEN DUNNEN, Wilfred F. A, WARNDERS, Frank-Jan, BROUWERS, Adrienne H, DE JONG, Johan R, PRICE, Patricia M, HOLLEMA, Harry, HOSPERS, Geke A. P

“…Non-invasive imaging of angiogenesis could ease the optimization of antiangiogenesis treatments for cancer. In this study, we evaluated the role of VEGF-PET as…”
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Clinical validation of FDG-PET/CT in the radiation treatment planning for patients with oesophageal cancer by Muijs, Christina T, Beukema, Jannet C, Woutersen, Dankert, Mul, Veronique E, Berveling, Maaike J, Pruim, Jan, van der Jagt, Eric J, Hospers, Geke A.P, Groen, Henk, Plukker, John Th, Langendijk, Johannes A

“…Abstract Background The aim of this prospective study was to determine the proportion of locoregional recurrences (LRRs) that could have been prevented if…”
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CD44, SHH and SOX2 as novel biomarkers in esophageal cancer patients treated with neoadjuvant chemoradiotherapy by Honing, Judith, Pavlov, Kirill V, Mul, Véronique E.M, Karrenbeld, Arend, Meijer, Coby, Faiz, Zohra, Smit, Justin K, Hospers, Geke A.P, Burgerhof, Johannes G.M, Kruyt, Frank A.E, Kleibeuker, Jan H, Plukker, John T.M

“…Abstract Background and purpose Neoadjuvant chemoradiotherapy (nCRT) improves survival in esophageal cancer (EC) patients, but the response to treatment is…”
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Everolimus Induces Rapid Plasma Glucose Normalization in Insulinoma Patients by Effects on Tumor As Well As Normal Tissues by Fiebrich, Helle‐Brit, Siemerink, Ester J.M., Brouwers, Adrienne H., Links, Thera P., Remkes, Wouter S., Hospers, Geke A.P., Vries, Elisabeth G. E.

“…Background. Mammalian target of rapamycin inhibitor everolimus administered to four insulinoma patients rapidly controlled hypoglycemia (Kulke et al., N Engl J…”
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Open-label, multicentre safety study of vemurafenib in 3219 patients with BRAFV600 mutation-positive metastatic melanoma: 2-year follow-up data and long-term responders' analysis by Blank, Christian U, Larkin, James, Arance, Ana M, Hauschild, Axel, Queirolo, Paola, Del Vecchio, Michele, Ascierto, Paolo A, Krajsova, Ivana, Schachter, Jacob, Neyns, Bart, Garbe, Claus, Chiarion Sileni, Vanna, Mandalà, Mario, Gogas, Helen, Espinosa, Enrique, Hospers, Geke A.P, Miller, Wilson H, Robson, Susan, Makrutzki, Martina, Antic, Vladan, Brown, Michael P

“…Abstract Background The orally available BRAF kinase inhibitor vemurafenib is an effective and tolerable treatment option for patients with metastatic melanoma…”
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Platelets and granulocytes, in particular the neutrophils, form important compartments for circulating vascular endothelial growth factor by KUSUMANTO, Yoka H, DAM, Wendy A, HOSPERS, Geke A. P, MEIJER, Coby, MULDER, Nanno H

“…The measurement of circulating vascular endothelial growth factor (VEGF) levels as a prognostic factor will gain increasing relevance in the diagnosis and…”
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Increased risk of thromboembolism in esophageal cancer patients treated with neoadjuvant chemoradiotherapy by Bosch, Dirk J., M.D, Van Dalfsen, Quirine A., M.D, Mul, Véronique E.M., M.D, Hospers, Geke A.P., M.D., Ph.D, Plukker, John Th.M., M.D., Ph.D

“…Abstract Background Neoadjuvant chemoradiotherapy (CRT) in esophageal cancer (EC) patients may increase the formation of thromboembolic events (TEEs). We…”
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Positron emission tomography imaging of oestrogen receptor-expression in endometrial stromal sarcoma supports oestrogen receptor-targeted therapy: Case report and review of the literature by van Kruchten, Michel, Hospers, Geke A.P, Glaudemans, Andor W.J.M, Hollema, Harry, Arts, Henriëtte J.G, Reyners, Anna K.L

“…Abstract Although the majority of endometrial stromal sarcomas (ESSs) express oestrogen receptor (ER), data on the efficacy of ER-targeted therapies are…”
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CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment by Tamas, Karin, Domanska, Urszula M, van Dijk, Tonnis H, Timmer-Bosscha, Hetty, Havenga, Klaas, Karrenbeld, Arend, Sluiter, Wim J, Beukema, Jannet C, van Vugt, Marcel A T M, de Vries, Elisabeth G E, Hospers, Geke A P, Walenkamp, Annemiek M E

“…Metastatic rectal cancer patients could benefit from novel therapeutic approaches. The signaling network formed by chemokines and their receptors can promote…”
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Molecular imaging for monitoring treatment response in breast cancer patients by Bensch, Frederike, van Kruchten, Michel, Lamberts, Laetitia E., Schröder, Carolien P., Hospers, Geke A.P., Brouwers, Adrienne H., van Vugt, Marcel A.T.M., de Vries, Elisabeth G.E.

“…Currently, tumour response following drug treatment is based on measurement of anatomical size changes. This is often done according to Response Evaluation…”
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Image Quality and Interpretation of [18F]-FES-PET: Is There any Effect of Food Intake? by Boers, Jorianne, Giatagana, Katerina, Schröder, Carolina P., Hospers, Geke A.P., de Vries, Erik F.J., Glaudemans, Andor W.J.M.

“…Background: High physiological 16α-[18F]-fluoro-17β-estradiol ([18F]-FES) uptake in the abdomen is a limitation of this positron emission tomography (PET)…”
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Endothelium in vitro: A review of human vascular endothelial cell lines for blood vessel-related research by BOUÏS, Diane, HOSPERS, Geke A. P, MEIJER, Coby, MOLEMA, Grietje, MULDER, Nanno H

“…Endothelial cells (EC) are currently used as in vitro model systems for various physiological and pathological processes, especially in angiogenesis research…”
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Longitudinal analysis of cytokine expression during neoadjuvant chemoradiotherapy and subsequent surgery in esophageal cancer patients by Bosch, Dirk J., MD.PhD, Wang, Da., MSc, Nijsten, Maarten W.N., MD.PhD, Mul, Véronique E.M., MD, Hospers, Geke A.P., MD.PhD, Burgerhof, Johannes G.M., MSc, Struys, Michel M.R.F., MD.PhD, Plukker, John Th.M., MD.PhD

“…Abstract Background The purpose of this study was to provide more insight in the course of cytokine concentrations related to pathological response (pR) and…”
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Effect of vemurafenib on a V600R melanoma brain metastasis by van den Brom, Rob R.H, de Vries, Elisabeth G.E, Schröder, Carolien P, Hospers, Geke A.P

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