Search Results - "Hoshino, Yuma"

CT scan findings of emphysema predict mortality in COPD by Haruna, Akane, Muro, Shigeo, Nakano, Yasutaka, Ohara, Tadashi, Hoshino, Yuma, Ogawa, Emiko, Hirai, Toyohiro, Niimi, Akio, Nishimura, Koichi, Chin, Kazuo, Mishima, Michiaki

“…Emphysematous change as assessed by CT imaging has been reported to correlate with COPD prognostic factors such as FEV(1) and diffusing capacity of the lung…”
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Redox Regulation in Aging Lungs and Therapeutic Implications of Antioxidants in COPD by Kiyokawa, Hirofumi, Hoshino, Yuma, Sakaguchi, Kazuhiro, Muro, Shigeo, Yodoi, Junji

“…Mammals, including humans, are aerobic organisms with a mature respiratory system to intake oxygen as a vital source of cellular energy. Despite the…”
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Abnormal swallowing reflex and COPD exacerbations by Terada, Kunihiko, Muro, Shigeo, Ohara, Tadashi, Kudo, Megumi, Ogawa, Emiko, Hoshino, Yuma, Hirai, Toyohiro, Niimi, Akio, Chin, Kazuo, Mishima, Michiaki

“…It is unclear whether an abnormal swallowing reflex affects COPD exacerbations. This study investigated the prevalence of abnormal swallowing reflexes and its…”
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Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD by Ohara, Tadashi, Hirai, Toyohiro, Muro, Shigeo, Haruna, Akane, Terada, Kunihiko, Kinose, Daisuke, Marumo, Satoshi, Ogawa, Emiko, Hoshino, Yuma, Niimi, Akio, Chin, Kazuo, Mishima, Michiaki

“…Osteoporosis is one of the important systemic features of COPD. Although COPD itself is regarded as one risk factor for osteoporosis, the relationship between…”
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Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice by Sato, Atsuyasu, Hoshino, Yuma, Hara, Tomijiro, Muro, Shigeo, Nakamura, Hajime, Mishima, Michiaki, Yodoi, Junji

“…Cigarette smoking is associated with the development of inflammatory lung diseases representing major health problems world-wide. We hypothesized that the…”
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Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease exacerbation by Tanabe, Naoya, Hoshino, Yuma, Marumo, Satoshi, Kiyokawa, Hirofumi, Sato, Susumu, Kinose, Daisuke, Uno, Kazuko, Muro, Shigeo, Hirai, Toyohiro, Yodoi, Junji, Mishima, Michiaki

“…Exacerbations of chronic obstructive pulmonary disease (COPD) are characterized by acute enhancement of airway neutrophilic inflammation under oxidative stress…”
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p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice by Marumo, Satoshi, Hoshino, Yuma, Kiyokawa, Hirofumi, Tanabe, Naoya, Sato, Atsuyasu, Ogawa, Emiko, Muro, Shigeo, Hirai, Toyohiro, Mishima, Michiaki

“…There is a need for agents that suppress inflammation and progression of chronic obstructive pulmonary disease. p38 mitogen-activated protein kinase (p38 MAPK)…”
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Relationship between peripheral airway function and patient-reported outcomes in COPD: a cross-sectional study by Haruna, Akane, Oga, Toru, Muro, Shigeo, Ohara, Tadashi, Sato, Susumu, Marumo, Satoshi, Kinose, Daisuke, Terada, Kunihiko, Nishioka, Michiyoshi, Ogawa, Emiko, Hoshino, Yuma, Hirai, Toyohiro, Chin, Kazuo, Mishima, Michiaki

“…Health status, dyspnea and psychological status are important clinical outcomes in chronic obstructive pulmonary disease (COPD). However, forced expiratory…”
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Emphysema distribution and annual changes in pulmonary function in male patients with chronic obstructive pulmonary disease by Tanabe, Naoya, Muro, Shigeo, Tanaka, Shiro, Sato, Susumu, Oguma, Tsuyoshi, Kiyokawa, Hirofumi, Takahashi, Tamaki, Kinose, Daisuke, Hoshino, Yuma, Kubo, Takeshi, Ogawa, Emiko, Hirai, Toyohiro, Mishima, Michiaki

“…The progression of chronic obstructive pulmonary disease (COPD) considerably varies among patients. Those with emphysema identified by quantitative computed…”
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Longitudinal study of spatially heterogeneous emphysema progression in current smokers with chronic obstructive pulmonary disease by Tanabe, Naoya, Muro, Shigeo, Sato, Susumu, Tanaka, Shiro, Oguma, Tsuyoshi, Kiyokawa, Hirofumi, Takahashi, Tamaki, Kinose, Daisuke, Hoshino, Yuma, Kubo, Takeshi, Hirai, Toyohiro, Mishima, Michiaki

“…Cigarette smoke is the main risk factor for emphysema, which is a key pathology in chronic obstructive pulmonary disease (COPD). Low attenuation areas (LAA) in…”
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Relationship between periodontitis-related antibody and frequent exacerbations in chronic obstructive pulmonary disease by Takahashi, Tamaki, Muro, Shigeo, Tanabe, Naoya, Terada, Kunihiko, Kiyokawa, Hirofumi, Sato, Susumu, Hoshino, Yuma, Ogawa, Emiko, Uno, Kazuko, Naruishi, Koji, Takashiba, Shogo, Mishima, Michiaki

“…To identify patients with chronic obstructive pulmonary disease (COPD) who are susceptible to frequent exacerbations is important. Although periodontitis…”
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Impact of COPD exacerbations on osteoporosis assessed by chest CT scan by Kiyokawa, Hirofumi, Muro, Shigeo, Oguma, Tsuyoshi, Sato, Susumu, Tanabe, Naoya, Takahashi, Tamaki, Kudo, Megumi, Kinose, Daisuke, Kondoh, Hiroshi, Kubo, Takeshi, Hoshino, Yuma, Ogawa, Emiko, Hirai, Toyohiro, Mishima, Michiaki

“…COPD pathology involves not only the lungs but also extrapulmonary abnormalities. Osteoporosis is one of the most important abnormalities because it may cause…”
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Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line by Hoshino, Y, Mio, T, Nagai, S, Miki, H, Ito, I, Izumi, T

“…Injury of the alveolar epithelium by cigarette smoke is presumed to be an important process in the pathogenesis of smoking-related pulmonary diseases. We…”
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Oxidative stress induced interleukin-32 mRNA expression in human bronchial epithelial cells by Kudo, Megumi, Ogawa, Emiko, Kinose, Daisuke, Haruna, Akane, Takahashi, Tamaki, Tanabe, Naoya, Marumo, Satoshi, Hoshino, Yuma, Hirai, Toyohiro, Sakai, Hiroaki, Muro, Shigeo, Date, Hiroshi, Mishima, Michiaki

“…Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction and persistent inflammation in the airways and lung parenchyma. Oxidative…”
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Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele by Ito, Isao, Nagai, Sonoko, Hoshino, Yuma, Muro, Shigeo, Hirai, Toyohiro, Tsukino, Mitsuhiro, Mishima, Michiaki

“…The finding that only 15 to 20% of cigarette smokers acquire COPD suggests that there is a genetic predisposition to the disease. Genetic polymorphism of the…”
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Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice by Ahsan, Md Kaimul, Okuyama, Hiroaki, Hoshino, Yuma, Oka, Shin-Ichi, Masutani, Hiroshi, Yodoi, Junji, Nakamura, Hajime

“…In nonalcoholic fatty liver disease, oxidative stress is believed to play a crucial role as a second-hit for the progression of simple steatosis to…”
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Recombinant human thioredoxin suppresses lipopolysaccharide-induced bronchoalveolar neutrophil infiltration in rat by Ueda, Shugo, Nakamura, Takayuki, Yamada, Akira, Teratani, Akie, Matsui, Nao, Furukawa, Suzuyo, Hoshino, Yuma, Narita, Makiko, Yodoi, Junji, Nakamura, Hajime

“…Human thioredoxin (TRX) is a multifunctional redox-active protein. We previously reported that the intraperitoneal administration of recombinant human…”
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Neurotropin Demonstrates Cytoprotective Effects in Lung Cells through the Induction of Thioredoxin-1 by Hoshino, Yuma, Nakamura, Takayuki, Sato, Atsuyasu, Mishima, Michiaki, Yodoi, Junji, Nakamura, Hajime

“…Neurotropin, a nonprotein extract from inflamed rabbit skin inoculated with vaccinia virus, is well known as an analgesic drug, but its cytoprotective effects…”
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Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD by Tanabe, Naoya, Muro, Shigeo, Oguma, Tsuyoshi, Sato, Susumu, Kiyokawa, Hirofumi, Takahashi, Tamaki, Kudo, Megumi, Kinose, Daisuke, Kubo, Takeshi, Hoshino, Yuma, Ogawa, Emiko, Hirai, Toyohiro, Mishima, Michiaki

“…Pharmacological lung volume reduction in COPD is an important goal in treatment with long-acting bronchodilators because in addition to airflow limitation,…”
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Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography by OHARA, Tadashi, HIRAI, Toyohiro, SATO, Susumu, TERADA, Kunihiko, KINOSE, Daisuke, HARUNA, Akane, MARUMO, Satoshi, NISHIOKA, Michiyoshi, OGAWA, Emiko, NAKANO, Yasutaka, HOSHINO, Yuma, ITO, Yutaka, MATSUMOTO, Hisako, NIIMI, Akio, MIO, Tadashi, CHIN, Kazuo, MURO, Shigeo, MISHIMA, Michiaki

“…Background and objective:  Chest CT has been widely used for the evaluation of structural changes in lung parenchyma and airways in cross‐sectional studies…”
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