Search Results - "Hoshino, Mikio"

Highly Efficient Green Organic Light-Emitting Diodes Containing Luminescent Three-Coordinate Copper(I) Complexes by Hashimoto, Masashi, Igawa, Satoshi, Yashima, Masataka, Kawata, Isao, Hoshino, Mikio, Osawa, Masahisa

“…A series of highly emissive three-coordinate copper(I) complexes, (dtpb)CuIX [X = Cl (1), Br (2), I (3); dtpb =1,2-bis(o-ditolylphosphino)benzene], were…”
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Neuronal subtype specification in the cerebellum and dorsal hindbrain by Hoshino, Mikio

“…In the nervous system, there are hundreds to thousands of neuronal cell types that have morphologically, physiologically, and histochemically different…”
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Neuronal Migration and AUTS2 Syndrome by Hori, Kei, Hoshino, Mikio

“…Neuronal migration is one of the pivotal steps to form a functional brain, and disorganization of this process is believed to underlie the pathology of…”
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Transit Amplifying Progenitors in the Cerebellum: Similarities to and Differences from Transit Amplifying Cells in Other Brain Regions and between Species by Miyashita, Satoshi, Hoshino, Mikio

“…Transit amplification of neural progenitors/precursors is widely used in the development of the central nervous system and for tissue homeostasis. In most…”
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Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking by Kawauchi, Takeshi, Sekine, Katsutoshi, Shikanai, Mima, Chihama, Kaori, Tomita, Kenji, Kubo, Ken-ichiro, Nakajima, Kazunori, Nabeshima, Yo-ichi, Hoshino, Mikio

“…Although membrane trafficking pathways are involved in basic cellular functions, the evolutionally expanded number of their related family proteins suggests…”
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AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders by Hori, Kei, Shimaoka, Kazumi, Hoshino, Mikio

“…Neurodevelopmental disorders (NDDs), including autism spectrum disorders (ASD) and intellectual disability (ID), are a large group of neuropsychiatric…”
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YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis by Pajtler, Kristian W., Wei, Yiju, Okonechnikov, Konstantin, Silva, Patricia B. G., Vouri, Mikaella, Zhang, Lei, Brabetz, Sebastian, Sieber, Laura, Gulley, Melissa, Mauermann, Monika, Wedig, Tatjana, Mack, Norman, Imamura Kawasawa, Yuka, Sharma, Tanvi, Zuckermann, Marc, Andreiuolo, Felipe, Holland, Eric, Maass, Kendra, Körkel-Qu, Huiqin, Liu, Hai-Kun, Sahm, Felix, Capper, David, Bunt, Jens, Richards, Linda J., Jones, David T. W., Korshunov, Andrey, Chavez, Lukas, Lichter, Peter, Hoshino, Mikio, Pfister, Stefan M., Kool, Marcel, Li, Wei, Kawauchi, Daisuke

“…YAP1 fusion-positive supratentorial ependymomas predominantly occur in infants, but the molecular mechanisms of oncogenesis are unknown. Here we show…”
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Molecular machinery governing GABAergic neuron specification in the cerebellum by Hoshino, Mikio

“…Although the cerebellum contains a relatively small variety of neurons, the molecular machinery governing neuronal generation and/or subtype specification is…”
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Vapochromic and Mechanochromic Tetrahedral Gold(I) Complexes Based on the 1,2-Bis(diphenylphosphino)benzene Ligand by Osawa, Masahisa, Kawata, Isao, Igawa, Satoshi, Hoshino, Mikio, Fukunaga, Takeo, Hashizume, Daisuke

“…Tetrahedral gold(I) complexes containing the diphosphane ligand (dppb=1,2‐bis(diphenylphosphino)benzene), [Au(dppb)2]X [X=Cl (1), Br (2), I (3), NO3 (4), BF4…”
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Cyclin D1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1 by Miyashita, Satoshi, Owa, Tomoo, Seto, Yusuke, Yamashita, Mariko, Aida, Shogo, Sone, Masaki, Ichijo, Kentaro, Nishioka, Tomoki, Kaibuchi, Kozo, Kawaguchi, Yoshiya, Taya, Shinichiro, Hoshino, Mikio

“…During development, neural progenitors are in proliferative and immature states; however, the molecular machinery that cooperatively controls both states…”
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Dysregulation of DPYSL2 expression by mTOR signaling in schizophrenia: Multi-level study of postmortem brain by Izumi, Ryuta, Hino, Mizuki, Nagaoka, Atsuko, Shishido, Risa, Kakita, Akiyoshi, Hoshino, Mikio, Kunii, Yasuto, Yabe, Hirooki

“…•DPYSL2 and mTOR-signaling cascade in schizophrenia brain were studied.•mTOR expression was increased in the PFC.•S6 expression was decreased in the PFC and…”
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The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2 by Ruffault, Pierre-Louis, D'Autréaux, Fabien, Hayes, John A, Nomaksteinsky, Marc, Autran, Sandra, Fujiyama, Tomoyuki, Hoshino, Mikio, Hägglund, Martin, Kiehn, Ole, Brunet, Jean-François, Fortin, Gilles, Goridis, Christo

“…Maintaining constant CO2 and H+ concentrations in the arterial blood is critical for life. The principal mechanism through which this is achieved in mammals is…”
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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140 by Ambrozkiewicz, Mateusz C., Schwark, Manuela, Kishimoto-Suga, Mika, Borisova, Ekaterina, Hori, Kei, Salazar-Lázaro, Andrea, Rusanova, Alexandra, Altas, Bekir, Piepkorn, Lars, Bessa, Paraskevi, Schaub, Theres, Zhang, Xin, Rabe, Tamara, Ripamonti, Silvia, Rosário, Marta, Akiyama, Haruhiko, Jahn, Olaf, Kobayashi, Tatsuya, Hoshino, Mikio, Tarabykin, Victor, Kawabe, Hiroshi

“…The establishment of axon-dendrite polarity is fundamental for radial migration of neurons during cortex development of mammals. We demonstrate that the E3…”
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Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons by Yamada, Mayumi, Seto, Yusuke, Taya, Shinichiro, Owa, Tomoo, Inoue, Yukiko U, Inoue, Takayoshi, Kawaguchi, Yoshiya, Nabeshima, Yo-Ichi, Hoshino, Mikio

“…In the cerebellum, the bHLH transcription factors Ptf1a and Atoh1 are expressed in distinct neuroepithelial regions, the ventricular zone (VZ) and the rhombic…”
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Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation by Owa, Tomoo, Taya, Shinichiro, Miyashita, Satoshi, Yamashita, Mariko, Adachi, Toma, Yamada, Koyo, Yokoyama, Miwa, Aida, Shogo, Nishioka, Tomoki, Inoue, Yukiko U, Goitsuka, Ryo, Nakamura, Takuro, Inoue, Takayoshi, Kaibuchi, Kozo, Hoshino, Mikio

“…Cerebellar granule cell precursors (GCPs) and granule cells (GCs) represent good models to study neuronal development. Here, we report that the transcription…”
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Glycosphingolipid metabolic reprogramming drives neural differentiation by Russo, Domenico, Della Ragione, Floriana, Rizzo, Riccardo, Sugiyama, Eiji, Scalabrì, Francesco, Hori, Kei, Capasso, Serena, Sticco, Lucia, Fioriniello, Salvatore, De Gregorio, Roberto, Granata, Ilaria, Guarracino, Mario R, Maglione, Vittorio, Johannes, Ludger, Bellenchi, Gian Carlo, Hoshino, Mikio, Setou, Mitsutoshi, D'Esposito, Maurizio, Luini, Alberto, D'Angelo, Giovanni

“…Neural development is accomplished by differentiation events leading to metabolic reprogramming. Glycosphingolipid metabolism is reprogrammed during neural…”
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Deficiency of AMPAR-Palmitoylation Aggravates Seizure Susceptibility by Itoh, Masayuki, Yamashita, Mariko, Kaneko, Masaki, Okuno, Hiroyuki, Abe, Manabu, Yamazaki, Maya, Natsume, Rie, Yamada, Daisuke, Kaizuka, Toshie, Suwa, Reiko, Sakimura, Kenji, Sekiguchi, Masayuki, Wada, Keiji, Hoshino, Mikio, Mishina, Masayoshi, Hayashi, Takashi

“…Synaptic AMPAR expression controls the strength of excitatory synaptic transmission and plasticity. An excess of synaptic AMPARs leads to epilepsy in response…”
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Cytoskeletal Regulation by AUTS2 in Neuronal Migration and Neuritogenesis by Hori, Kei, Nagai, Taku, Shan, Wei, Sakamoto, Asami, Taya, Shinichiro, Hashimoto, Ryoya, Hayashi, Takashi, Abe, Manabu, Yamazaki, Maya, Nakao, Keiko, Nishioka, Tomoki, Sakimura, Kenji, Yamada, Kiyofumi, Kaibuchi, Kozo, Hoshino, Mikio

“…Mutations in the Autism susceptibility candidate 2 gene (AUTS2), whose protein is believed to act in neuronal cell nuclei, have been associated with multiple…”
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Generation of Pax6-IRES-EGFP knock-in mouse via the cloning-free CRISPR/Cas9 system to reliably visualize neurodevelopmental dynamics by Inoue, Yukiko U., Morimoto, Yuki, Hoshino, Mikio, Inoue, Takayoshi

“…•We generate Pax6-IRES-EGFP knock-in mouse by the cloning-free CRISPR/Cas9 system.•EGFP expressions in the knock-in mice recapitulate the endogenous Pax6…”
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Unique Lewy pathology in myotonic dystrophy type 1 by Sano, Terunori, Kawazoe, Tomoya, Shioya, Ayako, Mori‐Yoshimura, Madoka, Oya, Yasushi, Maruo, Kazushi, Nishino, Ichizo, Hoshino, Mikio, Murayama, Shigeo, Saito, Yuko

“…Lewy body‐related α‐synucleinopathy (Lewy pathology) has been reported in patients with myotonic dystrophy (DM) type 1 (DM1), but no detailed report has…”
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