Search Results - "Hoshina, Chisato"
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Age prediction by methylation analysis of small amounts of DNA using locked nucleic acids
Published in Journal of forensic sciences (01-01-2023)“…Age prediction based on methylation analysis has been reported in many populations, with 10 ng or more of DNA usually required for each determination. In this…”
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Assessment of DNA degradation of buccal cells under humid conditions and DNA repair by DOP-PCR using locked nucleic acids
Published in Legal medicine (Tokyo, Japan) (01-11-2018)“…•The effect of humid conditions was evaluated based on two degradation ratios.•At 25 °C, the humidity significantly decreased 129:41- and 305:41-bp ratios…”
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Multidirectional analysis for a colchicine poisoning case revealed detail cause of death and its mechanism
Published in Legal medicine (Tokyo, Japan) (01-09-2022)“…•Tissue distribution of colchicine in humans died of acute colchicine poisoning.•Genetic analysis of stomach contents to reveal ingestion of Meadow…”
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Discrimination of haplotype in mitochondrial DNA mixtures using LNA-mediated PCR clamping
Published in Forensic science international : genetics (01-07-2019)“…•We developed a discrimination method of mtDNA mixtures by PCR clamping using LNA.•The specificity of LNA-containing probes was evaluated by predicting Tm…”
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Multicolor-based discrimination of 21 short tandem repeats and amelogenin using four fluorescent universal primers
Published in Analytical biochemistry (01-02-2016)“…The aim of this study was to develop a cost-effective genotyping method using high-quality DNA for human identification. A total of 21 short tandem repeats…”
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Brain stem hemorrhage due to cerebral amyloid angiopathy: The autopsy of a patient with Alzheimer’s disease at a young age
Published in Legal medicine (Tokyo, Japan) (01-03-2014)“…Abstract We report findings from an autopsy of a male in his 40s who died of a brain stem hemorrhage associated with cerebral amyloid angiopathy (CAA), senile…”
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DNA methylation-based age estimation and quantification of the degradation levels of bisulfite-converted DNA
Published in Legal medicine (Tokyo, Japan) (01-03-2024)“…•Age estimation model from buccal cells was constructed by pyrosequencing.•The mean absolute deviation for the 102 Japanese individuals was 3.88 years.•A…”
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Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells
Published in Biochemical and biophysical research communications (22-03-2013)“…► ER stress (ERS) response is involved in the pathogenesis of paraquat poisoning. ► Parkin may be a useful index of paraquat poisoning. ► TUDCA, a chemical…”
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Paraquat toxicity is attenuated by 4-phenylbutyrate-induced phosphorylation of ERK2 via PI3K in A549 cells
Published in Biochemical and biophysical research communications (05-09-2018)“…Paraquat (PQ) is a widely used herbicide in the world despite being highly toxic to humans. PQ causes fatal damage to multiple organs, especially the lungs…”
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HRD1 Levels Increased by Zonisamide Prevented Cell Death and Caspase-3 Activation Caused by Endoplasmic Reticulum Stress in SH-SY5Y Cells
Published in Journal of molecular neuroscience (01-03-2012)“…Zonisamide, which is commonly prescribed at high doses (200–400 mg/day) for the treatment of partial seizures, has recently been used at a low dose (25 mg/day)…”
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Rapid genotyping of 25 autosomal STRs in a Japanese population using fluorescent universal primers containing locked nucleic acids
Published in Journal of forensic and legal medicine (01-04-2015)“…Abstract Amplification of fluorescently labeled products is one of the most popular methods for genotyping genetic variations. Two-step amplification using…”
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