Search Results - "Hoshida, Yujin"

Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment by Hoshida, Yujin

“…Gene-expression signature-based disease classification and clinical outcome prediction has not been widely introduced in clinical medicine as initially…”
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Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine by Fujiwara, Naoto, Friedman, Scott L., Goossens, Nicolas, Hoshida, Yujin

“…Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies, are at a high risk of developing hepatocellular carcinoma (HCC)…”
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Hepatitis C virus-induced hepatocellular carcinoma by Goossens, Nicolas, Hoshida, Yujin

“…Hepatitis C virus (HCV) is a leading etiology of hepatocellular carcinoma (HCC). The interaction of HCV with its human host is complex and multilayered;…”
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MRI radiomics features predict immuno-oncological characteristics of hepatocellular carcinoma by Hectors, Stefanie J., Lewis, Sara, Besa, Cecilia, King, Michael J., Said, Daniela, Putra, Juan, Ward, Stephen, Higashi, Takaaki, Thung, Swan, Yao, Shen, Laface, Ilaria, Schwartz, Myron, Gnjatic, Sacha, Merad, Miriam, Hoshida, Yujin, Taouli, Bachir

“…Objective To assess the value of qualitative and quantitative MRI radiomics features for noninvasive prediction of immuno-oncologic characteristics and…”
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Molecular and immune landscape of hepatocellular carcinoma to guide therapeutic decision-making by Dhanasekaran, Renumathy, Suzuki, Hiroyuki, Lemaitre, Lea, Kubota, Naoto, Hoshida, Yujin

“…Liver cancer, primarily HCC, exhibits highly heterogeneous histological and molecular aberrations across tumors and within individual tumor nodules. Such…”
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A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer by Asgharpour, Amon, Cazanave, Sophie C, Pacana, Tommy, Seneshaw, Mulugeta, Vincent, Robert, Banini, Bubu A, Kumar, Divya Prasanna, Daita, Kalyani, Min, Hae-Ki, Mirshahi, Faridoddin, Bedossa, Pierre, Sun, Xiaochen, Hoshida, Yujin, Koduru, Srinivas V, Contaifer, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S, Sanyal, Arun J

“…Graphical abstract…”
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Genome-Wide Methylation Analysis and Epigenetic Unmasking Identify Tumor Suppressor Genes in Hepatocellular Carcinoma by Revill, Kate, Wang, Tim, Lachenmayer, Anja, Kojima, Kensuke, Harrington, Andrew, Li, Jinyu, Hoshida, Yujin, Llovet, Josep M, Powers, Scott

“…Background & Aims Epigenetic silencing of tumor suppressor genes contributes to the pathogenesis of hepatocellular carcinoma (HCC). To identify clinically…”
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Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum by Yamauchi, Mai, Morikawa, Teppei, Kuchiba, Aya, Imamura, Yu, Qian, Zhi Rong, Nishihara, Reiko, Liao, Xiaoyun, Waldron, Levi, Hoshida, Yujin, Huttenhower, Curtis, Chan, Andrew T, Giovannucci, Edward, Fuchs, Charles, Ogino, Shuji

“…Colorectal cancer is typically classified into proximal colon, distal colon and rectal cancer. Tumour genetic and epigenetic features differ by tumour…”
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International Liver Cancer Association (ILCA) White Paper on Biomarker Development for Hepatocellular Carcinoma by Singal, Amit G., Hoshida, Yujin, Pinato, David J., Marrero, Jorge, Nault, Jean-Charles, Paradis, Valerie, Tayob, Nabihah, Sherman, Morris, Lim, Young Suk, Feng, Ziding, Lok, Anna S., Rinaudo, Jo Ann, Srivastava, Sudhir, Llovet, Josep M., Villanueva, Augusto

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Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma by Finkin, Shlomi, Yuan, Detian, Stein, Ilan, Taniguchi, Koji, Weber, Achim, Unger, Kristian, Browning, Jeffrey L, Goossens, Nicolas, Nakagawa, Shigeki, Gunasekaran, Ganesh, Schwartz, Myron E, Kobayashi, Masahiro, Kumada, Hiromitsu, Berger, Michael, Pappo, Orit, Rajewsky, Klaus, Hoshida, Yujin, Karin, Michael, Heikenwalder, Mathias, Ben-Neriah, Yinon, Pikarsky, Eli

“…Ectopic lymphoid structures develop at sites of chronic inflammation and are generally thought to be beneficial in the control of cancer. Pikarsky and…”
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STIE: Single-cell level deconvolution, convolution, and clustering in in situ capturing-based spatial transcriptomics by Zhu, Shijia, Kubota, Naoto, Wang, Shidan, Wang, Tao, Xiao, Guanghua, Hoshida, Yujin

“…In in situ capturing-based spatial transcriptomics, spots of the same size and printed at fixed locations cannot precisely capture the randomly-located single…”
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Is Hepatocellular Cancer the Same Disease in Alcoholic and Nonalcoholic Fatty Liver Diseases? by Goossens, Nicolas, Hoshida, Yujin

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DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma by Villanueva, Augusto, Portela, Anna, Sayols, Sergi, Battiston, Carlo, Hoshida, Yujin, Méndez‐González, Jesús, Imbeaud, Sandrine, Letouzé, Eric, Hernandez‐Gea, Virginia, Cornella, Helena, Pinyol, Roser, Solé, Manel, Fuster, Josep, Zucman‐Rossi, Jessica, Mazzaferro, Vincenzo, Esteller, Manel, Llovet, Josep M.

“…Epigenetic deregulation has emerged as a driver in human malignancies. There is no clear understanding of the epigenetic alterations in hepatocellular…”
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Hepatitis C-related hepatocellular carcinoma in the era of new generation antivirals by Baumert, Thomas F, Jühling, Frank, Ono, Atsushi, Hoshida, Yujin

“…Hepatitis C virus infection is a major cause of hepatocellular carcinoma worldwide. Interferon has been the major antiviral treatment, yielding viral clearance…”
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Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma by Hoshida, Yujin, Fuchs, Bryan C, Bardeesy, Nabeel, Baumert, Thomas F, Chung, Raymond T

“…Summary Hepatitis C virus (HCV) is one of the major aetiologic agents that causes hepatocellular carcinoma (HCC) by generating an inflammatory, fibrogenic, and…”
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CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity by Fujiwara, Naoto, Nakagawa, Hayato, Enooku, Kenichiro, Kudo, Yotaro, Hayata, Yuki, Nakatsuka, Takuma, Tanaka, Yasuo, Tateishi, Ryosuke, Hikiba, Yohko, Misumi, Kento, Tanaka, Mariko, Hayashi, Akimasa, Shibahara, Junji, Fukayama, Masashi, Arita, Junichi, Hasegawa, Kiyoshi, Hirschfield, Hadassa, Hoshida, Yujin, Hirata, Yoshihiro, Otsuka, Motoyuki, Tateishi, Keisuke, Koike, Kazuhiko

“…Metabolic reprogramming of tumour cells that allows for adaptation to their local environment is a hallmark of cancer. Interestingly, obesity-driven and…”
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Notch Signaling Is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice by Villanueva, Augusto, Alsinet, Clara, Yanger, Kilangsungla, Hoshida, Yujin, Zong, Yiwei, Toffanin, Sara, Rodriguez–Carunchio, Leonardo, Solé, Manel, Thung, Swan, Stanger, Ben Z, Llovet, Josep M

“…Background & Aims The Notch signaling pathway is activated in leukemia and solid tumors (such as lung cancer), but little is known about its role in liver…”
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Omics‐derived hepatocellular carcinoma risk biomarkers for precision care of chronic liver diseases by Fujiwara, Naoto, Qian, Tongqi, Koneru, Bhuvaneswari, Hoshida, Yujin

“…Precise hepatocellular carcinoma (HCC) risk prediction will play increasingly important roles with the contemporary HCC etiologies, that is, non‐alcoholic…”
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Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling by Chernyavskaya, Yelena, Mudbhary, Raksha, Zhang, Chi, Tokarz, Debra, Jacob, Vinitha, Gopinath, Smita, Sun, Xiaochen, Wang, Shuang, Magnani, Elena, Madakashira, Bhavani P, Yoder, Jeffrey A, Hoshida, Yujin, Sadler, Kirsten C

“…Complex cytoplasmic nucleotide-sensing mechanisms can recognize foreign DNA based on a lack of methylation and initiate an immune response to clear the…”
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Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma by Fuchs, Bryan C., Hoshida, Yujin, Fujii, Tsutomu, Wei, Lan, Yamada, Suguru, Lauwers, Gregory Y., McGinn, Christopher M., DePeralta, Danielle K., Chen, Xintong, Kuroda, Toshihiko, Lanuti, Michael, Schmitt, Anthony D., Gupta, Supriya, Crenshaw, Andrew, Onofrio, Robert, Taylor, Bradley, Winckler, Wendy, Bardeesy, Nabeel, Caravan, Peter, Golub, Todd R., Tanabe, Kenneth K.

“…Hepatocellular carcinoma (HCC) is the most rapidly increasing cause of cancer‐related mortality in the United States. Because of the lack of viable treatment…”
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