Search Results - "Hosgood, S."

Renal Transplantation After Ex Vivo Normothermic Perfusion: The First Clinical Study by Nicholson, M. L., Hosgood, S. A.

“…Ex vivo normothermic perfusion (EVNP) is a novel method of preservation that restores circulation and allows an organ to regain function prior to…”
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Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors by Hosgood, S. A., Thompson, E., Moore, T., Wilson, C. H., Nicholson, M. L.

“…Background A significant proportion of donation after circulatory death (DCD) kidneys are declined for transplantation because of concerns over their quality…”
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Ex vivo normothermic perfusion for quality assessment of marginal donor kidney transplants by Hosgood, S. A., Barlow, A. D., Hunter, J. P., Nicholson, M. L.

“…Background A significant proportion of kidneys procured for transplantation are discarded because of concerns about their suitability. In this study ex vivo…”
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The First Clinical Case of Intermediate Ex Vivo Normothermic Perfusion in Renal Transplantation by Hosgood, S. A., Nicholson, M. L.

“…A short period of ex vivo normothermic perfusion (EVNP) immediately before transplantation can revive the kidney and reduce the effects of cold ischemic (CI)…”
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Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion by Hosgood, S. A., Saeb‐Parsy, K., Hamed, M. O., Nicholson, M. L.

“…We report the successful transplantation of a pair of human kidneys that were declined for transplantation due to inadequate in situ perfusion but subsequently…”
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Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications by Albert, C., Bracaglia, L., Koide, A., DiRito, J., Lysyy, T., Harkins, L., Edwards, C., Richfield, O., Grundler, J., Zhou, K., Denbaum, E., Ketavarapu, G., Hattori, T., Perincheri, S., Langford, J., Feizi, A., Haakinson, D., Hosgood, S. A., Nicholson, M. L., Pober, J. S., Saltzman, W. M., Koide, S., Tietjen, G. T.

“…Vascular endothelial cells (ECs) play a central role in the pathophysiology of many diseases. The use of targeted nanoparticles (NPs) to deliver therapeutics…”
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Hydrogen sulphide ameliorates ischaemia-reperfusion injury in an experimental model of non-heart-beating donor kidney transplantation by Hosgood, S. A., Nicholson, M. L.

“…Background: Therapies to alleviate ischaemia–reperfusion (IR) injury have an important role in kidney transplantation. This study used a porcine model of…”
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Effects of hydrogen sulphide in an experimental model of renal ischaemia-reperfusion injury by Hunter, J. P., Hosgood, S. A., Patel, M., Rose, R., Read, K., Nicholson, M. L.

“…Background: Renal ischaemia–reperfusion injury (IRI) is a major cause of acute renal failure and renal transplant dysfunction. The aim of this study was to…”
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Risk factors for transplant renal artery stenosis after live donor transplantation by Nicholson, M. L., Yong, C., Trotter, P. B., Grant, L., Hosgood, S. A.

“…Background Renal transplant surgeons are making increasing use of live donor kidneys with multiple renal arteries. This study aimed to identify independent…”
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Ex Vivo Normothermic Perfusion of Declined Human Kidneys After Inadequate In Situ Perfusion by Hosgood, S. A., Nicholson, M. L.

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Use of Ex Vivo Normothermic Perfusion for Quality Assessment of Discarded Human Donor Pancreases by Barlow, A. D., Hamed, M. O., Mallon, D. H., Brais, R. J., Gribble, F. M., Scott, M. A., Howat, W. J., Bradley, J. A., Bolton, E. M., Pettigrew, G. J., Hosgood, S. A., Nicholson, M. L., Saeb‐Parsy, K.

“…A significant number of pancreases procured for transplantation are deemed unsuitable due to concerns about graft quality and the associated risk of…”
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Mitochondria-targeted antioxidant MitoQ ameliorates ischaemia-reperfusion injury in kidney transplantation models by Hamed, M, Logan, A, Gruszczyk, A V, Beach, T E, James, A M, Dare, A J, Barlow, A, Martin, J, Georgakopoulos, N, Gane, A M, Crick, K, Fouto, D, Fear, C, Thiru, S, Dolezalova, N, Ferdinand, J R, Clatworthy, M R, Hosgood, S A, Nicholson, M L, Murphy, M P, Saeb-Parsy, K

“…Ischaemia-reperfusion (IR) injury makes a major contribution to graft damage during kidney transplantation. Oxidative damage to mitochondria is an early event…”
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Experimental renal preservation by normothermic resuscitation perfusion with autologous blood by Bagul, A., Hosgood, S. A., Kaushik, M., Kay, M. D., Waller, H. L., Nicholson, M. L.

“…Background: Normothermic perfusion (NP) has the potential to improve metabolic support and maintain the viability of ischaemically damaged organs. This study…”
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Hypothermic machine perfusion after static cold storage does not improve the preservation condition in an experimental porcine kidney model by Hosgood, S. A., Mohamed, I. H., Bagul, A., Nicholson, M. L.

“…Background: Combining hypothermic techniques, as a more practical approach to preservation, may enhance the condition of kidneys donated after cardiac death…”
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Response to “Past, Present, and Future of Dynamic Kidney and Liver Preservation and Resuscitation” by Hosgood, S. A., Callaghan, C., Wilson, C., Nicholson, M. L.

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The Carrel patch clamp for renal transplantation by Radford, Lac, Kleverlaan, T F, Hosgood, S A, Nicholson, M L

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Ischaemic conditioning reduces kidney injury in an experimental large-animal model of warm renal ischaemia by Hunter, J. P., Hosgood, S. A., Barlow, A. D., Nicholson, M. L.

“…Background Ischaemic conditioning, using short repeated sequences of intermittent ischaemia, is a strategy that may ameliorate ischaemia–reperfusion injury…”
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Leucocyte depletion improves renal function during reperfusion using an experimental isolated haemoperfused organ preservation system by Harper, S., Hosgood, S., Kay, M., Nicholson, M.

“…Background: Leucocytes have been implicated as mediators of renal ischaemia–reperfusion injury. This study aimed to demonstrate the effect of white cells in…”
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Ex vivo normothermic perfusion of isolated segmental porcine bowel: a novel functional model of the small intestine by Hamed, M O, Barlow, A D, Dolezalova, N, Khosla, S, Sagar, A, Gribble, F M, Davies, S, Murphy, M P, Hosgood, S A, Nicholson, M L, Saeb-Parsy, K

“…Abstract Background There is an unmet need for suitable ex vivo large animal models in experimental gastroenterology and intestinal transplantation. This study…”
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Renal transplant fibrosis at ONE month post transplantation is a significant indicator of graft survival at one year post transplantation by Ismail, W, Aswad, M, Hosgood, S, Nicholson, M

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