Search Results - "Horváth, Gergő"

Multiple Timescale Dynamic Analysis of Functionally-Impairing Mutations in Human Ileal Bile Acid-Binding Protein by Horváth, Gergő, Balterer, Bence, Micsonai, András, Kardos, József, Toke, Orsolya

“…Human ileal bile acid-binding protein (hI-BABP) has a key role in the enterohepatic circulation of bile salts. Its two internal binding sites exhibit positive…”
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GABA, glutamine, glutamate oxidation and succinic semialdehyde dehydrogenase expression in human gliomas by Hujber, Zoltán, Horváth, Gergő, Petővári, Gábor, Krencz, Ildikó, Dankó, Titanilla, Mészáros, Katalin, Rajnai, Hajnalka, Szoboszlai, Norbert, Leenders, William P J, Jeney, András, Tretter, László, Sebestyén, Anna

“…Bioenergetic characterisation of malignant tissues revealed that different tumour cells can catabolise multiple substrates as salvage pathways, in response to…”
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Bioenergetic Impairment of Triethylene Glycol Dimethacrylate- (TEGDMA-) Treated Dental Pulp Stem Cells (DPSCs) and Isolated Brain Mitochondria are Amended by Redox Compound Methylene Blue by Mikulás, Krisztina, Komlódi, Timea, Földes, Anna, Sváb, Gergely, Horváth, Gergő, Nagy, Ádám, Ambrus, Attila, Gyulai-Gaál, Szabolcs, Gera, István, Hermann, Péter, Varga, Gábor, Tretter, László

“…Background: Triethylene glycol dimethacrylate (TEGDMA) monomers released from resin matrix are toxic to dental pulp cells, induce apoptosis, oxidative stress…”
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TP53 mutation hits energy metabolism and increases glycolysis in breast cancer by Harami-Papp, Hajnalka, Pongor, Lőrinc S, Munkácsy, Gyöngyi, Horváth, Gergő, Nagy, Ádám M, Ambrus, Attila, Hauser, Péter, Szabó, András, Tretter, László, Győrffy, Balázs

“…Promising new hallmarks of cancer is alteration of energy metabolism that involves molecular mechanisms shifting cancer cells to aerobe glycolysis. Our goal…”
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Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation by Horváth, Gergő, Egyed, Orsolya, Tang, Changguo, Kovács, Mihály, Micsonai, András, Kardos, József, Toke, Orsolya

“…Human ileal bile acid-binding protein (hI-BABP) has a key role in the intracellular transport of bile salts. To explore the role of histidine protonation in…”
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Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I by Mikulás, Krisztina, Hermann, Péter, Gera, István, Komlódi, Timea, Horváth, Gergő, Ambrus, Attila, Tretter, László

“…•Dental resin monomer TEGDMA impairs mitochondrial functions.•TEGDMA inhibits Complex I and respiration via NADH-producing substrates.•TEGDMA stimulates H2O2…”
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Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR by Horváth, Gergő, Bencsura, Ákos, Simon, Ágnes, Tochtrop, Gregory P, DeKoster, Gregory T, Covey, Douglas F, Cistola, David P, Toke, Orsolya

“…Besides aiding digestion, bile salts are important signal molecules exhibiting a regulatory role in metabolic processes. Human ileal bile acid binding protein…”
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Reverse and Forward Electron Flow-Induced H2O2 Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals by Horváth, Gergő, Sváb, Gergely, Komlódi, Tímea, Ravasz, Dora, Kacsó, Gergely, Doczi, Judit, Chinopoulos, Christos, Ambrus, Attila, Tretter, László

“…α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that…”
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Sodium selective ion channel formation in living cell membranes by polyamidoamine dendrimer by Nyitrai, Gabriella, Keszthelyi, Tamás, Bóta, Attila, Simon, Ágnes, Tőke, Orsolya, Horváth, Gergő, Pál, Ildikó, Kardos, Julianna, Héja, László

“…Polyamidoamine (PAMAM) dendrimers are highly charged hyperbranched protein-like polymers that are known to interact with cell membranes. In order to disclose…”
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Novel mitochondrial transition pore inhibitor N‐methyl‐4‐isoleucine cyclosporin is a new therapeutic option in acute pancreatitis by Tóth, Emese, Maléth, József, Závogyán, Noémi, Fanczal, Júlia, Grassalkovich, Anna, Erdős, Réka, Pallagi, Petra, Horváth, Gergő, Tretter, László, Bálint, Emese Réka, Rakonczay, Zoltán, Venglovecz, Viktória, Hegyi, Péter

“…Key points •Bile acids, ethanol and fatty acids affect pancreatic ductal fluid and bicarbonate secretion via mitochondrial damage, ATP depletion and calcium…”
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Structural insight into a partially unfolded state preceding aggregation in an intracellular lipid‐binding protein by Horváth, Gergő, Biczók, László, Majer, Zsuzsa, Kovács, Mihály, Micsonai, András, Kardos, József, Toke, Orsolya

“…Human ileal bile acid‐binding protein (I‐BABP) has a key role in the intracellular transport and metabolic targeting of bile salts. Similar to other members of…”
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Substrate oxidation differences in human glioma cells and their potential clinical significance by Sebestyén, Anna, Hujber, Zoltán, Petővári, Gábor, Krencz, Ildikó, Dankó, Titanilla, Horváth, Gergő, Mészáros, Katalin, Rajnai, Hajnalka, Tretter, László, Jeney, András

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Genetic inhibition of cyclophilin D protects against bile acid or ethanol and fatty acid induced pancreatic ductal epithelial cell damage in mice by Tóth, Emese, Maléth, József, Erdős, Réka, Závogyán, Noémi, Tretter, László, Horváth, Gergő, Rakonczay, Zoltán, Hegyi, Péter

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Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate Dehydrogenase Heterozygote Knock Out Animals by Horváth, Gergő, Sváb, Gergely, Komlódi, Tímea, Ravasz, Dora, Kacsó, Gergely, Doczi, Judit, Chinopoulos, Christos, Ambrus, Attila, Tretter, László

“…α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that…”
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Temperature Dependence of Backbone Dynamics in Human Ileal Bile Acid-Binding Protein: Implications for the Mechanism of Ligand Binding by Horváth, Gergő, Egyed, Orsolya, Toke, Orsolya

“…Human ileal bile acid-binding protein (I-BABP), a member of the family of intracellular lipid binding proteins plays a key role in the cellular trafficking and…”
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9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) reduces the severity of acute pancreatitis via inhibition of the mitochondrial transition pore by Tóth, Emese, Maleth, József, Závogyán, Noémi, Erdös, Réka, Tretter, László, Horváth, Gergő, Bálint, Emese Réka, Rakonczay, Zoltán, Venglovecz, Viktória, Hegyi, Péter

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Internal Motions and Exchange Processes in Human Ileal Bile Acid Binding Protein As Studied by Backbone 15 N Nuclear Magnetic Resonance Spectroscopy by Horváth, Gergő, Király, Péter, Tárkányi, Gábor, Toke, Orsolya

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The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy by Daradics, Noemi, Horvath, Gergo, Tretter, Laszlo, Paal, Agnes, Fulop, Andras, Budai, Andras, Szijarto, Attila

“…Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) is a modification of two-stage hepatectomy profitable for patients with…”
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The effects of physical prehabilitation: Improved liver regeneration and mitochondrial function after ALPPS operation in a rodent model by Fard‐Aghaie, Mohammad H., Budai, Andras, Daradics, Noemi, Horvath, Gergo, Oldhafer, Karl J., Szijarto, Attila, Fulop, Andras

“…Background To identify the role of physical prehabilitation (PP) in liver regeneration, mitochondrial function, biogenesis, and inflammatory response was…”
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Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry by Fischer, Michael J, Horvath, Gergo, Krismer, Martin, Gnaiger, Erich, Goebel, Georg, Pesta, Dominik H

“…Myofascial trigger points (MTrPs) are hyperirritable areas in the fascia of the affected muscle, possibly related to mitochondrial impairment. They can result…”
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