Search Results - "Horton, S J"

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia by Giotopoulos, G, Chan, W-I, Horton, S J, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, P J, Göttgens, B, Van Deursen, J M, Cole, P A, Huntly, B J P

“…Growing evidence links abnormal epigenetic control to the development of hematological malignancies. Accordingly, inhibition of epigenetic regulators is…”
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Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia by Dawson, M A, Gudgin, E J, Horton, S J, Giotopoulos, G, Meduri, E, Robson, S, Cannizzaro, E, Osaki, H, Wiese, M, Putwain, S, Fong, C Y, Grove, C, Craig, J, Dittmann, A, Lugo, D, Jeffrey, P, Drewes, G, Lee, K, Bullinger, L, Prinjha, R K, Kouzarides, T, Vassiliou, G S, Huntly, B J P

“…Recent evidence suggests that inhibition of bromodomain and extra-terminal (BET) epigenetic readers may have clinical utility against acute myeloid leukemia…”
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MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny by Horton, S J, Jaques, J, Woolthuis, C, van Dijk, J, Mesuraca, M, Huls, G, Morrone, G, Vellenga, E, Schuringa, J J

“…The MLL–AF9 fusion gene is associated with aggressive leukemias of both the myeloid and lymphoid lineage in infants, whereas in adults, this translocation is…”
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Relaxin Modulates Proinflammatory Cytokine Secretion from Human Decidual Macrophages by HORTON, J. S, YAMAMOTO, S. Y, BRYANT-GREENWOOD, G. D

“…Relaxin (RLN) is a systemic hormone from the corpus luteum, and its levels remain low during normal human gestation. Indeed, elevation of circulating RLN has…”
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Relaxin augments the inflammatory IL6 response in the choriodecidua by Horton, J.S, Yamamoto, S.Y, Bryant-Greenwood, G.D

“…Abstract Intrauterine infection frequently leads to preterm birth (PTB), with the pathophysiology involving activation of the innate immune system and its…”
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A Near-Deterministic Mutational Hotspot in Pseudomonas fluorescens Is Constructed by Multiple Interacting Genomic Features by Shepherd, M J, Horton, J S, Taylor, T B

“…Abstract Mutation—whilst stochastic—is frequently biased toward certain loci. When combined with selection, this results in highly repeatable and predictable…”
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The use of phage display to distinguish insulin autoantibody (IAA) from insulin antibody (IA) idiotypes by DEVENDRA, D, GALLOWAY, T. S, HORTON, S. J, EVENDEN, A, KELLER, U, WILKIN, T. J

“…Radiobinding assays (RBA) are unable to differentiate insulin autoantibodies (IAA) from insulin antibodies (IA). We sought to establish whether random peptide…”
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The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis by Osaki, H, Walf-Vorderwülbecke, V, Mangolini, M, Zhao, L, Horton, S J, Morrone, G, Schuringa, J J, de Boer, J, Williams, O

“…The most frequent chromosomal translocations in pediatric acute myeloid leukemia affect the 11q23 locus and give rise to mixed lineage leukemia ( MLL ) fusion…”
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Exploring the idiotypes of insulin antibodies as markers for remission in Type 1 diabetes by Devendra, D., Galloway, T. S., Horton, S. J., Wilkin, T. J.

“…Aims  Complete or partial remission can occur in newly diagnosed Type 1 diabetes patients. We created idiotype‐specific reagents to explore the idiotypes of…”
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Recurring enteric peritonitis associated with non-perforating colon carcinoma by Stevenson, J A, Jurado, J L, Belli, D D, Horton, S J

“…Peritonitis of enteric origin may occur during treatment with peritoneal dialysis due to visceral perforation or injury or, in the absence of perforation, due…”
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Exercise intervention for a musculoskeletal disorder in an oral health student: a case report by Horton, S J, Wade, K J

“…to describe and evaluate the effect of an exercise self-management programme for an oral health student who was suffering from a musculoskeletal disorder which…”
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Biomass of tomato seedlings exposed to an allelopathic phenolic acid and enriched atmospheric carbon dioxide by Shafer, S.R. (North Carolina State Univ., Raleigh, NC (USA). Dept. of Plant Pathology), Blum, U, Horton, S.J, Hesterberg, D.L

“…Increased atmospheric CO^sub 2^ can affect plant growth, so competition among plants may be influenced. Allelopathy is one mechanism involved in plant…”
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Carbon dioxide enrichment and nitrogen fertilization effects on cotton (Gossypium hirsutum L.) plant residue chemistry and decomposition by Booker, Fitzgerald L., Shafer, Steven R., Wei, Cai-Miao, Horton, Stephanie J.

“…Increased atmospheric carbon dioxide (CO₂) concentration will likely cause changes in plant productivity and composition that might affect soil decomposition…”
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Regulation of dikaryon-expressed genes by FRT1 in the basidiomycete Schizophyllum commune by Horton, J.S, Palmer, G.E, Smith, W.J

“…The gene FRT1 has previously been shown to induce homokaryotic fruiting in transformation recipients of the basidiomycete Schizophyllum commune. In this paper,…”
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A mushroom-inducing DNA sequence isolated from the Basidiomycete, Schizophyllum commune by Horton, J.S. (University of Vermont, Burlington, VT), Raper, C.A

“…A DNA sequence capable of inducing the de novo development of fruiting bodies (mushrooms) when integrated into the genome of unmated, nonfruiting strains of…”
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Acute locked thoracic spine: treatment with a modified SNAG by Horton, S.J.

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Effects of rhizobium, arbuscular mycorrhizal fungi and anion content of simulated rain on subterranean clover by Shafer, S.R., Schoeneberger, M.M., Horton, S.J., Davey, C.B., Miller, J.E.

“…An experiment was conducted to determine the extent to which rhizobia, mycorrhizal fungi, and anions in simulated rain affect plant growth response to acid…”
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Genome sequence of the model mushroom Schizophyllum commune by Kües, Ursula, Schmutz, Jeremy, Ohm, Robin A, Lilly, Walt W, vanKuyk, Patricia A, Lucas, Susan, Raudaskoski, Marjatta, Kothe, Erika, Record, Eric, Stajich, Jason E, Horton, J Stephen, Lindquist, Erika, Henrissat, Bernard, Coutinho, Pedro M, Knabe, Nicole, Gathman, Allen C, Aerts, Andrea, Lugones, Luis G, Schwarze, Francis W M R, Grigoriev, Igor V, Bartholomew, Kirk A, Lombard, Vincent, Wösten, Han A B, Magnuson, Jon K, de Vries, Ronald P, Piumi, François, de Jong, Jan F, Erdmann, Susann, Salamov, Asaf, Levasseur, Anthony, Baker, Scott E, Fowler, Thomas J

“…Much remains to be learned about the biology of mushrooms, which are an important source of food as well as secondary metabolites and enzymes of…”
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Recent advances in acute myeloid leukemia stem cell biology by HORTON, Sarah J, HUNTLY, Brian J. R

“…The existence of cancer stem cells has long been postulated, but was proven less than 20 years ago following the demonstration that only a small sub-fraction…”
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Pulsed-field gel electrophoretic analysis of Schizophyllum commune chromosomal DNA by Horton, J.S. (Vermont Univ., Burlington (USA). Dept. of Microbiology and Molecular Genetics), Raper, C.A

“…Six chromosomal DNA bands of Schizophyllum commune have been resolved using transverse alternating field electrophoresis. The estimated sizes of the…”
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