Search Results - "Horton, Megan. K."
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Vital signs assessed in initial clinical encounters predict COVID-19 mortality in an NYC hospital system
Published in Scientific reports (09-12-2020)“…Timely and effective clinical decision-making for COVID-19 requires rapid identification of risk factors for disease outcomes. Our objective was to identify…”
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Brain anomalies in children exposed prenatally to a common organophosphate pesticide
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-2012)“…Prenatal exposure to chlorpyrifos (CPF), an organophosphate insecticide, is associated with neurobehavioral deficits in humans and animal models. We…”
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Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior
Published in Environment international (01-12-2018)“…Metal exposure alters neurodevelopmental outcomes; little is known about critical windows of susceptibility when exposure exerts the strongest effect. To…”
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Integrated measures of lead and manganese exposure improve estimation of their joint effects on cognition in Italian school-age children
Published in Environment international (01-01-2021)“…•Joint effects of metals are strongly affected by medium used to measure exposure.•Combined exposure measures (MMBs) improve detection of joint effects of…”
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Biospecimens and the ABCD study: Rationale, methods of collection, measurement and early data
Published in Developmental cognitive neuroscience (01-08-2018)“…Biospecimen collection in the Adolescent Brain Cognitive Development (ABCD) study – of hair samples, shed deciduous (baby) teeth, and body fluids – will serve…”
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Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor
Published in Neurotoxicology (Park Forest South) (01-12-2015)“…•Prenatal chlorpyrifos exposure is associated with tremor in middle childhood, which may be a sign of the insecticide's effects on nervous system…”
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Early-life dentine manganese concentrations and intrinsic functional brain connectivity in adolescents: A pilot study
Published in PloS one (14-08-2019)“…Maturational processes in the developing brain are disrupted by exposure to environmental toxicants, setting the stage for deviant developmental trajectories…”
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Prenatal metal mixture concentrations and reward motivation in children
Published in Neurotoxicology (Park Forest South) (01-01-2022)“…•We examined prenatal metal mixture concentrations and reward motivation in children.•Metal mixture concentrations were associated with increased reward…”
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Impact of prenatal exposure to piperonyl butoxide and permethrin on 36-month neurodevelopment
Published in Pediatrics (Evanston) (01-03-2011)“…Recent pesticide-monitoring results suggest that a shift in residential pesticide exposure from organophosphorus insecticides to pyrethroid insecticides has…”
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Functional connectivity of the reading network is associated with prenatal polybrominated diphenyl ether concentrations in a community sample of 5 year-old children: A preliminary study
Published in Environment international (01-01-2020)“…•Polybrominated Diphenyl Ethers (PBDE), used as flame retardants, cross the placenta.•PBDE exposure predicts reduced efficiency of the brain’s reading…”
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Topological network properties of resting-state functional connectivity patterns are associated with metal mixture exposure in adolescents
Published in Frontiers in neuroscience (06-02-2023)“…Adolescent exposure to neurotoxic metals adversely impacts cognitive, motor, and behavioral development. Few studies have addressed the underlying brain…”
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COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study
Published in Translational psychiatry (02-10-2024)“…Coronavirus disease 2019 (COVID-19) has been associated with brain functional, structural, and cognitive changes that persist months after infection. Most…”
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Neuro-environmental interactions: a time sensitive matter
Published in Frontiers in computational neuroscience (08-01-2024)“…The assessment of resting state (rs) neurophysiological dynamics relies on the control of sensory, perceptual, and behavioral environments to minimize…”
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Functional changes in neural mechanisms underlying post-traumatic stress disorder in World Trade Center responders
Published in Translational psychiatry (11-07-2023)“…World Trade Center (WTC) responders exposed to traumatic and environmental stressors during rescue and recovery efforts have a high prevalence of chronic…”
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Endocrine-Disrupting Effects of Cattle Feedlot Effluent on an Aquatic Sentinel Species, the Fathead Minnow
Published in Environmental health perspectives (01-03-2004)“…Over the last decade, research has examined the endocrine-disrupting action of various environmental pollutants, including hormones, pharmaceuticals, and…”
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The Luria-Nebraska Neuropsychological Battery Neuromotor Tasks: From Conventional to Image-Derived Measures
Published in Brain sciences (08-06-2022)“…Background: Sensorimotor difficulties significantly interfere with daily activities, and when undiagnosed in early life, they may increase the risk of later…”
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Cocaine addiction severity exacerbates the negative association of lifetime lead exposure with blood pressure levels: Evidence from a pilot study
Published in Environmental disease (01-07-2019)“…Background: High blood pressure (BP) is associated independently with cocaine use and lead exposure. It is not known whether cocaine use and lead exposure act…”
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Extending the Distributed Lag Model framework to handle chemical mixtures
Published in Environmental research (01-07-2017)“…Distributed Lag Models (DLMs) are used in environmental health studies to analyze the time-delayed effect of an exposure on an outcome of interest. Given the…”
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CO-occurring exposure to perchlorate, nitrate and thiocyanate alters thyroid function in healthy pregnant women
Published in Environmental research (01-11-2015)“…Adequate maternal thyroid function during pregnancy is necessary for normal fetal brain development, making pregnancy a critical window of vulnerability to…”
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Prenatal PM2.5 exposure and behavioral development in children from Mexico City
Published in Neurotoxicology (Park Forest South) (01-12-2020)“…•We investigated the association between prenatal PM2.5 and behavioral development.•Behavioral development was assessed in 4-6 year olds using the…”
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