Search Results - "Horton, M N"
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Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer
Published in Drug metabolism and disposition (01-03-1995)“…The metabolism of tamoxifen was examined in human liver homogenate and human Hep G2 cell line preparations by LC/electro spray ionization/MS. Several…”
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Reduced genotoxicity of [D5-ethyl]-tamoxifen implicates alpha-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen
Published in Carcinogenesis (New York) (01-08-1994)“…A proposed mechanism for the metabolic activation of tamoxifen to electrophilic species that form DNA adducts leading to liver cancer involves…”
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N-Demethylation accompanies α-hydroxylation in the metabolic activation of tamoxifen in rat liver cells
Published in Carcinogenesis (New York) (01-10-1999)“…Previous work has shown that a major route of activation of tamoxifen to DNA-binding products in rat liver cells is via α-hydroxylation leading to modification…”
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The deuterium isotope effect for the alpha-hydroxylation of tamoxifen by rat liver microsomes accounts for the reduced genotoxicity of [D5-ethyl]tamoxifen
Published in Carcinogenesis (New York) (01-04-1995)“…This study describes the application of on line HPLC-electrospray ionization MS in the structural determination of the metabolites formed following incubation…”
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A near-field scanning optical microscopy study of the photoluminescence from GaN films
Published in Applied physics letters (02-12-1996)“…We have achieved spatially resolved photoluminescence from GaN films using a near-field scanning optical microscope (NSOM). GaN films grown by hydride vapor…”
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Spectroscopic ellipsometry and low-temperature reflectance: complementary analysis of GaN thin films
Published in Thin solid films (01-02-1998)“…We report spectroscopic ellipsometry (SE) and low-temperature reflectance data on epitaxial GaN thin-film samples covering the widest range of tensile and…”
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Spectral analysis of above-, below-, and near-bandedge phenomena in GaN thin films
Published in Materials science & engineering. B, Solid-state materials for advanced technology (18-12-1997)“…We report spectroscopic ellipsometry (SE) and low-temperature reflectance data on epitaxial GaN thin film samples covering the widest range of tensile and…”
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Journal Article Conference Proceeding -
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Variation of GaN valence bands with biaxial stress and quantification of residual stress
Published in Applied physics letters (14-04-1997)“…Low-temperature reflectance data on epitaxial GaN thin-film samples covering the widest range of tensile and compressive stress (−3.8–3.5 kbar) thus far…”
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Synthesis and DNA Reactivity of α-Hydroxylated Metabolites of Nonsteroidal Antiestrogens
Published in Chemical research in toxicology (01-04-1998)“…Tamoxifen [(E)-1-(4-(2-(N,N-dimethylamino)ethoxy)phenyl)-1,2-diphenylbut-1-ene], a nonsteroidal antiestrogen, induces liver tumors in rats by a genotoxic…”
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Spectroscopic ellipsometry and low-temperature reflectance : complementary analysis of GaN thin films
Published in Thin solid films (1998)Get full text
Conference Proceeding -
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More about Suction Pumps
Published in Scientific American (07-03-1868)Get full text
Magazine Article -
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Letter 2 -- No Title
Published in Scientific American (07-03-1868)“…MESSRS. EDITORS:--On page 67, Vol. XVIII., your corre spondent endeavors to place some strictures upon my statements in a former communication. He says, that…”
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Magazine Article -
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Relative Size of Pump Barrels and Tubes
Published in Scientific American (21-12-1867)Get full text
Magazine Article