Search Results - "Horton, Janet"
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Breast Cancer Biology: Clinical Implications for Breast Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-01-2018)“…Historically, prognosis and treatment decision making for breast cancer patients have been dictated by the anatomic extent of tumor spread. However, in recent…”
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Management of the Axilla in Early-Stage Breast Cancer: Ontario Health (Cancer Care Ontario) and ASCO Guideline
Published in Journal of clinical oncology (20-09-2021)“…PURPOSETo provide recommendations on the best strategies for the management and on the best timing and treatment (surgical and radiotherapeutic) of the axilla…”
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Postmastectomy Conundrum
Published in International journal of radiation oncology, biology, physics (01-08-2017)Get full text
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Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer
Published in International journal of radiation oncology, biology, physics (15-03-2018)“…To determine the role of macrophage polarization on the response of inflammatory breast cancer (IBC) cells to radiation and whether modulation of macrophage…”
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Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers
Published in International journal of radiation oncology, biology, physics (15-07-2015)“…Purpose Women with biologically favorable early-stage breast cancer are increasingly treated with accelerated partial breast radiation (PBI). However,…”
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Society of Surgical Oncology–American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer
Published in International journal of radiation oncology, biology, physics (01-03-2014)“…Purpose To convene a multidisciplinary panel of breast experts to examine the relationship between margin width and ipsilateral breast tumor recurrence (IBTR)…”
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Magnetic Resonance Imaging as a Predictor of Pathologic Response in Patients Treated With Neoadjuvant Systemic Treatment for Operable Breast Cancer: Translational Breast Cancer Research Consortium Trial 017
Published in Cancer (15-05-2013)“…Increased pathologic complete response (pCR) rates observed with neoadjuvant chemotherapy (NCT) for some subsets of patients with invasive breast cancer have…”
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Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study
Published in Journal of clinical oncology (01-05-2018)“…Purpose Locoregional control for inflammatory breast cancers and chest wall recurrences is suboptimal, which has motivated interest in radiosensitization to…”
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The use of adjuvant radiotherapy in elderly patients with early‐stage breast cancer: Changes in practice patterns after publication of Cancer and Leukemia Group B 9343
Published in Cancer (15-01-2015)“…BACKGROUND The Cancer and Leukemia Group B (CALGB) 9343 randomized phase 3 trial established lumpectomy and adjuvant therapy with tamoxifen alone, rather than…”
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Exploratory composite endpoint demonstrates benefit of trilaciclib across multiple clinically meaningful components of myeloprotection in patients with small cell lung cancer
Published in International journal of cancer (01-10-2021)“…Chemotherapy‐induced myelosuppression is an acute, dose‐limiting toxicity of chemotherapy regimens used in the treatment of extensive‐stage small cell lung…”
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First, Do No Harm
Published in International journal of radiation oncology, biology, physics (01-02-2019)Get full text
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Pharmacokinetic Drug–Drug Interaction Studies Between Trilaciclib and Midazolam, Metformin, Rifampin, Itraconazole, and Topotecan in Healthy Volunteers and Patients with Extensive-Stage Small-Cell Lung Cancer
Published in Clinical drug investigation (01-08-2022)“…Background and Objective Trilaciclib is a cyclin-dependent kinase 4/6 inhibitor indicated to decrease the incidence of chemotherapy-induced myelosuppression in…”
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Preoperative Single Fraction Partial Breast Radiotherapy for Early-Stage Breast Cancer
Published in International journal of radiation oncology, biology, physics (2012)“…Purpose Several recent series evaluating external beam accelerated partial breast irradiation (PBI) have reported adverse cosmetic outcomes, possibly related…”
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Regional Nodal Irradiation in the Modern Era of Breast Cancer Management
Published in International journal of radiation oncology, biology, physics (01-06-2018)Get full text
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Automatic Planning of Whole Breast Radiation Therapy Using Machine Learning Models
Published in Frontiers in oncology (07-08-2019)“…To develop an automatic treatment planning system for whole breast radiation therapy (WBRT) based on two intensity-modulated tangential fields, enabling…”
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Assessment of Treatment Response With Diffusion-Weighted MRI and Dynamic Contrast-Enhanced MRI in Patients With Early-Stage Breast Cancer Treated With Single-Dose Preoperative Radiotherapy: Initial Results
Published in Technology in cancer research & treatment (01-10-2016)“…Single-dose preoperative stereotactic body radiotherapy is a novel radiotherapy technique for the early-stage breast cancer, and the treatment response pattern…”
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Lessons Learned From Hurricane Maria in Puerto Rico: Practical Measures to Mitigate the Impact of a Catastrophic Natural Disaster on Radiation Oncology Patients
Published in Practical Radiation Oncology (01-09-2019)“…Although the wind, rain, and flooding of Hurricane Maria in Puerto Rico abated shortly after its landfall on September 20, 2017, the disruption of the…”
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Oncology Scan—Quality of Life and Patient Perspectives During Breast Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-02-2015)Get full text
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Findings on Surveillance Imaging After Preoperative Partial Breast Irradiation for Early Stage Breast Cancer
Published in International journal of radiation oncology, biology, physics (15-11-2018)“…To evaluate the mammographic sequelae of preoperative accelerated partial breast irradiation (APBI) delivered via either stereotactic radiosurgery or a…”
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How Low Can We Go—and Should We? Risk Reduction for Minimal-Volume DCIS
Published in Annals of surgical oncology (01-02-2018)Get full text
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