Search Results - "Horten, Bruce"

HER2 Amplification Ratios by Fluorescence In Situ Hybridization and Correlation with Immunohistochemistry in a Cohort of 6556 Breast Cancer Tissues by Owens, Marilyn A., Horten, Bruce C., Da Silva, Moacyr M.

“…To analyze HER2 amplification in a large cohort of diagnostic breast cancer specimens, fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC)…”
Get full text

Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies by Rouleau, Cecile, Gianolio, Diego A, Smale, Robert, Roth, Stephanie D, Krumbholz, Roy, Harper, Jay, Munroe, Kenneth J, Green, Tessa L, Horten, Bruce C, Schmid, Steven M, Teicher, Beverly A

“…Endosialin/TEM1/CD248 is a cell surface protein expressed at high levels by the malignant cells of about 50% of sarcomas and neuroblastomas. The antibody-drug…”
Get full text

Gain of copy number and amplification of the RET gene in lung cancer by Yang, Hai-Su, Horten, Bruce

“…RET rearrangement represents a unique molecular subset of lung cancer. The identification of specific clinicopathologic characteristics and RET gene status…”
Get full text

Endosialin Protein Expression and Therapeutic Target Potential in Human Solid Tumors: Sarcoma versus Carcinoma by ROULEAU, Cecile, CURIEL, Maritza, HASEGAWA, Kazumasa, ISHIDA, Isao, KATAOKA, Shiro, THURBERG, Beth L, MEHRAEIN, Khodadad, HORTEN, Bruce, MILLER, Glenn, TEICHER, Beverly A, WEBER, William, SMALE, Robert, KURTZBERG, Leslie, MASCARELLO, James, BERGER, Carol, WALLAR, Gina, BAGLEY, Rebecca, HONMA, Nakayuki

“…Purpose: Endosialin/CD248/tumor endothelial marker 1 is expressed in stromal cells, endothelial cells, and pericytes in various tumors; however, few studies…”
Get full text

Abstract 663: Clinical performance and utilization of 3 PD-L1 immunohistochemical assays by Anderson, Steven M., Horten, Bruce, McCune, Bryan, Paler, Ronald

“…Abstract Three different PD-L1 immunohistochemical (IHC) assays have recently been approved to help guide treatment decisions regarding anti-PD-1 (Keytruda®,…”
Get full text

Companion and complementary diagnostics for PD-L1 expression assessment in non-small cell lung cancer by Anderson, Steven M., Horten, Bruce, McCune, Bryan, Paler, Ronald

“…Abstract only…”
Get full text

Validation of the Lung Subtyping Panel in Multiple Fresh-Frozen and Formalin-Fixed, Paraffin-Embedded Lung Tumor Gene Expression Data Sets by Faruki, Hawazin, Mayhew, Gregory M, Fan, Cheng, Wilkerson, Matthew D, Parker, Scott, Kam-Morgan, Lauren, Eisenberg, Marcia, Horten, Bruce, Hayes, D Neil, Perou, Charles M, Lai-Goldman, Myla

“…Context .- A histologic classification of lung cancer subtypes is essential in guiding therapeutic management. Objective .- To complement morphology-based…”
Get full text

Endosialin is expressed in high grade and advanced sarcomas: Evidence from clinical specimens and preclinical modeling by ROULEAU, Cecile, SMALE, Robert, CURIEL, Maritza, YIREN, BAGLEY, Rebecca G, WALLAR, Gina, MILLER, Glenn, SCHMID, Steven, HORTEN, Bruce, TEICHER, Beverly A, FU, Yao-Shi, GUODONG HUI, FEI WANG, HUTTO, Elizabeth, FOGLE, Robert, JONES, Craig M, KRUMBHOLZ, Roy, ROTH, Stephanie

“…We previously surveyed the expression of endosialin/ CD248/TEM-1 by immunohistochemistry in human clinical specimens of sarcomas and documented expression in…”
Get full text

Abstract LB-274: Clinical significance of MUC1, MUC2 and CK17 expression patterns in the diagnosis of pancreatic carcinoma by Yang, Haisu, Tamayo, Rosalba, Horten, Bruce, DaSilva, Moacyr, Gangi, Maryann, Vazquez, Evelyn, Joseph, Daisy, Okamoto, Patricia, Scholl, Thomas

“…Abstract Pancreatic cancer is characterized by aggressive growth and treatment resistance. Identification of unique biomarkers for diagnosis and prognosis is…”
Get full text

Multifocal varicella-zoster virus leukoencephalitis temporally remote from herpes zoster by Horten, B, Price, R W, Jimenez, D

“…Two patients with cancer, one with Hodgkin's disease and the other with a granulosa cell tumor of the ovary, developed a progressive, eventually fatal…”
Get more information

Endosialin: A novel malignant cell therapeutic target for neuroblastoma by ROULEAU, Cecile, SMALE, Robert, DUNHAM, Sarah, KRUMBHOLZ, Roy, CURIEL, Maritza, WALLAR, Gina, MASCARELLO, James, CAMPOS-RIVERA, Juanita, HORTEN, Bruce, SCHMID, Steven, MILLER, Glenn, TEICHER, Beverly A, SANCHO, Jose, FU, Yao-Shi, KURTZBERG, Leslie, WEBER, William, KRUGER, Ariel, JONES, Craig, ROTH, Stephanie, BORMANN, Christy

“…Endosialin emerged recently as a potential therapeutic target for sarcoma. Since some sarcoma subtypes, such as Ewing's sarcoma, show characteristics of…”
Get full text

Abstract C80: Characterizing models for personalized medicine: Endosialin in sarcoma from cultured cells to mice to humans by Rouleau, Cecile, Smale, Robert, Jones, Craig, Gianolio, Diego, Horten, Bruce, Schmid, Steve, Miller, Glenn, Teicher, Beverly A.

“…Abstract A survey of endosialin by IHC was previously conducted in 250 clinical specimens of cancer, revealing a key difference between sarcomas and…”
Get full text

Abstract 5251: Endosialin: A novel cell surface therapeutic target for early-stage and late-stage neuroblastoma by Rouleau, Cecile, Smale, Robert, Kurtzberg, Leslie, Weber, William, Jones, Craig, Roth, Stephanie, Bormann, Christy, Dunham, Sarah, Krumbholz, Roy, Curiel, Maritza, Wallar, Gina, Fu, Yao-Shi, Horten, Bruce, Gianolio, Diego, Schmid, Steven, Miller, Glenn, Teicher, Beverly A.

“…Abstract Hypothesis: Endosialin emerged recently as a potential marker and therapeutic target for adult and pediatric sarcoma. Given evidence of a possible…”
Get full text

Progressive multifocal leukoencephalopathy: a burnt-out case by Price, R W, Nielsen, S, Horten, B, Rubino, M, Padgett, B, Walker, D

“…A patient with Hodgkin's disease developed progressive multifocal leukoencephalopathy (PML), documented by brain biopsy to be associated with JC virus…”
Get more information

Meningeal gliomatosis: a review of 12 cases by Yung, W A, Horten, B C, Shapiro, W R

“…Diffuse or multifocal invasion of the leptomeninges by malignant glioma (meningeal gliomatosis) is believed to be rare. From 1971 through 1977, 11 of 52…”
Get more information

Current status of HER2 testing by Di Leo, Angelo, Dowsett, Mitch, Horten, Bruce, Penault-Llorca, Frédérique

“…HER2 gene amplification and receptor overexpression by tumors seems to be associated with poorer prognosis and may be predictive of response to certain…”
Get more information

Progressive white matter destruction following irradiation of an extracranial neoplasm by Rottenberg, D A, Horten, B, Kim, J H, Posner, J B

“…Although numerous "cures# have been reported following surgical extirpation of symptomatic foci of cerebral radiation nerosis, delayed progressive white matter…”
Get more information

Fungal aneurysms of intracranial vessels by Horten, B C, Abbott, G F, Porro, R S

“…Intracranial fungal aneurysms arise from major cerebral arteries. Fungi directly invade vessel walls from the luminal surface (fungal emboli) or from the…”
Get more information

Primary cerebral neuroblastoma. A clinicopathological study of 35 cases by Horten, B C, Rubinstein, L J

“…A series of 35 primary cerebral neuroblastoma is reported. These rare tumours occur most often in children in the first half of the first decade. Grossly the…”
Get more information

Meningiomas with conspicuous plasma cell-lymphocytic components: a report of five cases by Horten, B C, Urich, H, Stefoski, D

“…Five meningeal neoplasms grossly resembling meningiomas but histologically containing meningothelial cells together with abundant plasma cells and lymphocytes…”
Get more information