Search Results - "Horstman, Debra"

Essential role of the tyrosine kinase substrate phospholipase C-γ1 in mammalian growth and development by Ji, Qun-sheng, Winnier, Glenn E., Niswender, Kevin D., Horstman, Debra, Wisdom, Ron, Magnuson, Mark A., Carpenter, Graham

“…The activation of many tyrosine kinases leads to the phosphorylation and activation of phospholipase C-γ1 (PLC-γ1). To examine the biological function of this…”
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A Point Mutation of the $\alpha_2$-Adrenoceptor That Blocks Coupling to Potassium But Not Calcium Currents by Surprenant, Annmarie, Horstman, Debra A., Akbarali, Hamid, Limbird, Lee E.

“…The $\alpha_{2A}$-adrenergic receptor (adrenoceptor) was stably expressed in AtT20 mouse pituitary tumor cells; adrenoceptor agonists inhibited adenylyl…”
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Essential Role of the Tyrosine Kinase Substrate Phospholipase C-γ 1 in Mammalian Growth and Development by Ji, Qun-Sheng, Winnier, Glenn E., Niswender, Kevin D., Horstman, Debra, Wisdom, Ron, Magnuson, Mark A., Carpenter, Graham

“…The activation of many tyrosine kinases leads to the phosphorylation and activation of phospholipase C-γ 1 (PLC-γ 1). To examine the biological function of…”
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The Influence of Deletion Mutations on Phospholipase C-γ1 Activity by Horstman, Debra A., Chattopadhyay, Ansuman, Carpenter, Graham

“…Phospholipase C-γ1, a substrate for many growth factor receptor and nonreceptor tyrosine kinases, produces second messenger molecules that are elements of…”
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A point mutation of the α2-adrenoceptor that blocks coupling to potassium but not calcium currents by SURPRENANT, A, HORSTMAN, D. A, AKBARALI, H, LIMBIRD, L. E

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An aspartate conserved among G-protein receptors confers allosteric regulation of α2-adrenergic receptors by sodium by HORSTMAN, D. A, BRANDON, S, WILSON, A. L, GUYER, C. A, GRAGOE, E. J, LIMBIRD, L. E

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Enhanced Phospholipase C-γ 1 Activity Produced by Association of Independently Expressed X and Y Domain Polypeptides by Horstman, Debra A., DeStefano, Kristine, Carpenter, Graham

“…The X and Y domains of phospholipase C (PLC)-γ 1, which are conserved in all mammalian phosphoinositide-specific PLC isoforms and are proposed to interact to…”
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Action of Phosphatidylinositol-specific Phospholipase Cγ1 on Soluble and Micellar Substrates by Chun Zhou, Debra Horstman, Graham Carpenter, Mary F. Roberts

“…The kinetics of PI-PLCγ1 toward a water-soluble substrate (inositol 1,2-cyclic phosphate, cIP) and phosphatidylinositol (PI) in detergent mixed micelles were…”
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Action of Phosphatidylinositol-specific Phospholipase Cγ1 on Soluble and Micellar Substrates by Zhou, Chun, Horstman, Debra, Carpenter, Graham, Roberts, Mary F.

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Cloning, sequencing, and expression of the gene encoding the porcine α2-adrenergic receptor : allosteric modulation by Na+, H+, and amiloride analogs by GUYER, C. A, HORSTMAN, D. A, WILSON, A. L, CLARK, J. D, CRAGOE, E. J, LIMBIRD, L. E

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How do inositol phosphates regulate calcium signaling? by Putney, Jr, J W, Takemura, H, Hughes, A R, Horstman, D A, Thastrup, O

“…Activation of a variety of cell surface receptors results in the phospholipase C-catalyzed hydrolysis of the minor plasma membrane phospholipid…”
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Enhanced phospholipase C-gamma1 activity produced by association of independently expressed X and Y domain polypeptides by Horstman, D A, DeStefano, K, Carpenter, G

“…The X and Y domains of phospholipase C (PLC)-gamma1, which are conserved in all mammalian phosphoinositide-specific PLC isoforms and are proposed to interact…”
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Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development by Ji, Q S, Winnier, G E, Niswender, K D, Horstman, D, Wisdom, R, Magnuson, M A, Carpenter, G

“…The activation of many tyrosine kinases leads to the phosphorylation and activation of phospholipase C-gamma1 (PLC-gamma1). To examine the biological function…”
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Baculovirus Expression and Purification of Rat 10-Formyltetrahydrofolate Dehydrogenase by Krupenko, S.A., Horstman, D.A., Wagner, C., Cook, R.J.

“…The liver cytosolic enzyme, 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (EC 1.5.1.6) catalyzes two reactions: the NADP +-dependent oxidation of…”
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ATP-induced calcium mobilization and inositol 1,4,5-trisphosphate formation in H-35 hepatoma cells by Horstman, Debra A., Tennes, Karin A., Putney, James W.

“…Addition of ATP (but not epinephrine, angiotensin II, vasopressin, or platelet-activating factor) to H-35 hepatoma cells whose cellular lipids have been…”
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Inositol phosphate metabolism and cellular signal transduction by Putney, Jr, J W, Hughes, A R, Horstman, D A, Takemura, H

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Inositol phosphate metabolism and signal transduction by Hughes, A R, Horstman, D A, Takemura, H, Putney, Jr, J W

“…Activation of a variety of cell surface receptors results in a biphasic increase in the cytoplasmic Ca2+ concentration, due to the release or mobilization of…”
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