Search Results - "Horrighs, A"
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Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells
Published in International Journal of Obesity (01-06-2011)“…Objective: Pigment epithelium-derived factor (PEDF) is a multifunctional protein with neurotrophic and anti-angiogenic properties. More recently it became…”
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Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle
Published in Diabetologia (01-04-2009)“…Aims/hypothesis Cannabinoid type 1 receptor (CB1R) antagonists such as rimonabant (Rim) represent a novel approach to treat obesity and related metabolic…”
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Hypoxia reduces the response of human adipocytes towards TNFα resulting in reduced NF-κB signaling and MCP-1 secretion
Published in International Journal of Obesity (01-07-2012)“…Objective: Obesity is associated with adipose tissue hypoxia, and is thought to be linked to the chronic low-grade inflammation of adipose tissue, although the…”
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Chemerin Is a Novel Adipocyte-Derived Factor Inducing Insulin Resistance in Primary Human Skeletal Muscle Cells
Published in Diabetes (New York, N.Y.) (01-12-2009)“…Chemerin Is a Novel Adipocyte-Derived Factor Inducing Insulin Resistance in Primary Human Skeletal Muscle Cells Henrike Sell 1 , Jurga Laurencikiene 2 , Annika…”
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Hypoxia reduces the response of human adipocytes towards TNF[alpha] resulting in reduced NF-[kappa]B signaling and MCP-1 secretion
Published in International Journal of Obesity (01-07-2012)“…Obesity is associated with adipose tissue hypoxia, and is thought to be linked to the chronic low-grade inflammation of adipose tissue, although the precise…”
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Journal Article