Search Results - "Horrevorts, Sophie K"

Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways by van Wigcheren, Glenn F., Cuenca-Escalona, Jorge, Stelloo, Suzan, Brake, Julia, Peeters, Eline, Horrevorts, Sophie.K., Frölich, Siebren, Ramos-Tomillero, Iván, Wesseling-Rozendaal, Yvonne, van Herpen, Carla M.L., van de Stolpe, Anja, Vermeulen, Michiel, de Vries, I. Jolanda M., Figdor, Carl G., Flórez-Grau, Georgina

“…Imbalanced immune responses are a prominent hallmark of cancer and autoimmunity. Overactive as well as suppressed immunological activity is evidenced to…”
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Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells by Dusoswa, Sophie A., Horrevorts, Sophie K., Ambrosini, Martino, Kalay, Hakan, Paauw, Nanne J., Nieuwland, Rienk, Pegtel, Michiel D., Würdinger, Tom, Van Kooyk, Yvette, Garcia-Vallejo, Juan J.

“…Glioblastoma is the most prevalent and aggressive primary brain tumour for which total tumour lysate-pulsed dendritic cell vaccination is currently under…”
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Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I by Horrevorts, Sophie K, Duinkerken, Sanne, Bloem, Karien, Secades, Pablo, Kalay, Hakan, Musters, René J, van Vliet, Sandra J, García-Vallejo, Juan J, van Kooyk, Yvette

“…DC-SIGN is an antigen uptake receptor expressed on dendritic cells (DCs) with specificity for glycans present on a broad variety of pathogens and is capable of…”
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Cisplatin inhibits frequency and suppressive activity of monocytic myeloid-derived suppressor cells in cancer patients by Van Wigcheren, Glenn F., De Haas, Nienke, Mulder, Tom A., Horrevorts, Sophie K., Bloemendal, Martine, Hins-Debree, Simone, Mao, Yumeng, Kiessling, Rolf, van Herpen, Carla M.L., Flórez-Grau, Georgina, Hato, Stanleyson V., De Vries, I. Jolanda M.

“…Cancer immunotherapies have induced long-lasting responses in cancer patients including those with melanoma and head and neck squamous cell carcinoma (HNSCC)…”
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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets by Duinkerken, Sanne, Horrevorts, Sophie K., Kalay, Hakan, Ambrosini, Martino, Rutte, Lisa, de Gruijl, Tanja D., Garcia-Vallejo, Juan J., van Kooyk, Yvette

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Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition by Stolk, Dorian A., Horrevorts, Sophie K., Schetters, Sjoerd T.T., Kruijssen, Laura J.W., Duinkerken, Sanne, Keuning, Eelco, Ambrosini, Martino, Kalay, Hakan, van de Ven, Rieneke, Garcia-Vallejo, Juan J., de Gruijl, Tanja D., van Vliet, Sandra J., van Kooyk, Yvette

“…Induction of tumor-specific cytotoxic CD8+ T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility…”
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Outer membrane vesicles engineered to express membrane-bound antigen program dendritic cells for cross-presentation to CD8+ T cells by Schetters, Sjoerd T.T., Jong, Wouter S.P., Horrevorts, Sophie K., Kruijssen, Laura J.W., Engels, Steef, Stolk, Dorian, Daleke-Schermerhorn, Maria H., Garcia-Vallejo, Juan, Houben, Diane, Unger, Wendy W.J., den Haan, Joke M.M., Luirink, Joen, van Kooyk, Yvette

“…[Display omitted] Outer membrane vesicles (OMVs) are vesicular nano-particles produced by Gram-negative bacteria that are recently being explored as vaccine…”
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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets by Duinkerken, Sanne, Horrevorts, Sophie K, Kalay, Hakan, Ambrosini, Martino, Rutte, Lisa, de Gruijl, Tanja D, Garcia-Vallejo, Juan J, van Kooyk, Yvette

“…The human skin is an attractive anti-tumor vaccination site due to the vast network of dendritic cell (DC) subsets that carry antigens to the draining lymph…”
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Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination by Horrevorts, Sophie K., Stolk, Dorian A., van de Ven, Rieneke, Hulst, Myrthe, van Het Hof, Bert, Duinkerken, Sanne, Heineke, Marieke H., Ma, Wenbin, Dusoswa, Sophie A., Nieuwland, Rienk, Garcia-Vallejo, Juan J., van de Loosdrecht, Arjan A., de Gruijl, Tanja D., van Vliet, Sandra J., van Kooyk, Yvette

“…Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of…”
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Glycan-Modified Melanoma-Derived Apoptotic Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination by Horrevorts, Sophie K, Stolk, Dorian A, Ven, Rieneke van de, Hulst, Myrthe, Hof, Bert van Het, Duinkerken, Sanne, Heineke, Marieke H, Ma, Wenbin, Dusoswa, Sophie A, Nieuwland, Rienk, Garcia-Vallejo, Juan J, Loosdrecht, Arjan A van de, de Gruijl, Tanja D, Vliet, Sandra J van, van Kooyk, Yvette

“…Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of…”
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Apoptotic vesicles as tumor vaccine by Horrevorts, Sophie K, Garcia-Vallejo, Juan J, van Vliet, Sandra J, van de Loosdrecht, Arjan A, van Kooyk, Yvette, de Gruijl, Tanja D

“…[...]IFNγ, secreted by Th1 cells upregulates MHC class I that increases antigen presentation to CTLs. Besides the ex vivo expansion of tumor-specific T cells…”
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