Search Results - "Horowitz, Mark"

1.1 Computing's energy problem (and what we can do about it) by Horowitz, Mark

“…Our challenge is clear: The drive for performance and the end of voltage scaling have made power, and not the number of transistors, the principal factor…”
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The serotonin theory of depression: a systematic umbrella review of the evidence by Moncrieff, Joanna, Cooper, Ruth E., Stockmann, Tom, Amendola, Simone, Hengartner, Michael P., Horowitz, Mark A.

“…The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered…”
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Are we repeating mistakes of the past? A review of the evidence for esketamine by Horowitz, Mark A., Moncrieff, Joanna

“…Esketamine has been licensed for ‘treatment-resistant depression’ in the USA, UK and Europe. Licensing trials did not establish efficacy: two trials were…”
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Step change in guidance on withdrawing antidepressants by Horowitz, Mark A

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Defining the Computational Structure of the Motion Detector in Drosophila by Clark, Damon A., Bursztyn, Limor, Horowitz, Mark A., Schnitzer, Mark J., Clandinin, Thomas R.

“…Many animals rely on visual motion detection for survival. Motion information is extracted from spatiotemporal intensity patterns on the retina, a paradigmatic…”
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Volumetric Image Registration From Invariant Keypoints by Rister, Blaine, Horowitz, Mark A., Rubin, Daniel L.

“…We present a method for image registration based on 3D scale- and rotation-invariant keypoints. The method extends the scale invariant feature transform (SIFT)…”
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The Vaccine-Hesitant Moment by Horowitz, Mark E., Larson, Heidi J.

“…To the Editor: As a family physician providing Covid-19 vaccination to my patients and to others who have located me through city and national vaccine search…”
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Gradually tapering off antipsychotics: lessons for practice from case studies and neurobiological principles by Horowitz, Mark A, Moncrieff, Joanna

“…There has been an increasing focus on deprescribing in psychiatry recently, particularly of antipsychotic medication, with recognition that not all patients…”
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Neuroimmune and neuroendocrine abnormalities in depression: two sides of the same coin by Horowitz, Mark A., Zunszain, Patricia A.

“…Major depressive disorder has been linked to alterations in several interacting systems, particularly with respect to neuroendocrine and neuroinflammatory…”
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Osteoimmunology: Interactions of the Bone and Immune System by Lorenzo, Joseph, Horowitz, Mark, Choi, Yongwon

“…Bone and the immune system are both complex tissues that respectively regulate the skeleton and the body’s response to invading pathogens. It has now become…”
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Microtubule Organization Determines Axonal Transport Dynamics by Yogev, Shaul, Cooper, Roshni, Fetter, Richard, Horowitz, Mark, Shen, Kang

“…Axonal microtubule (MT) arrays are the major cytoskeleton substrate for cargo transport. How MT organization, i.e., polymer length, number, and minus-end…”
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Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate by Fan, Yi, Hanai, Jun-ichi, Le, Phuong T., Bi, Ruiye, Maridas, David, DeMambro, Victoria, Figueroa, Carolina A., Kir, Serkan, Zhou, Xuedong, Mannstadt, Michael, Baron, Roland, Bronson, Roderick T., Horowitz, Mark C., Wu, Joy Y., Bilezikian, John P., Dempster, David W., Rosen, Clifford J., Lanske, Beate

“…Intermittent PTH administration builds bone mass and prevents fractures, but its mechanism of action is unclear. We genetically deleted the PTH/PTHrP…”
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Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems by Ren, Jing, Friedmann, Drew, Xiong, Jing, Liu, Cindy D., Ferguson, Brielle R., Weerakkody, Tanya, DeLoach, Katherine E., Ran, Chen, Pun, Albert, Sun, Yanwen, Weissbourd, Brandon, Neve, Rachael L., Huguenard, John, Horowitz, Mark A., Luo, Liqun

“…The dorsal raphe (DR) constitutes a major serotonergic input to the forebrain and modulates diverse functions and brain states, including mood, anxiety, and…”
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Are we repeating mistakes of the past? A review of the evidence for esketamine - CORRIGENDUM by Horowitz, Mark A, Moncrieff, Joanna

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Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling by Festa, Eric, Fretz, Jackie, Berry, Ryan, Schmidt, Barbara, Rodeheffer, Matthew, Horowitz, Mark, Horsley, Valerie

“…In mammalian skin, multiple types of resident cells are required to create a functional tissue and support tissue homeostasis and regeneration. The cells that…”
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Fluoxetine Can Cause Epileptogenesis and Aberrant Neurogenesis in Male Wild-Type Mice by Musaelyan, Ksenia, Horowitz, Mark A, McHugh, Stephen, Szele, Francis G

“…Antidepressants in general, and fluoxetine in particular, increase adult hippocampal neurogenesis (AHN) in mice. Here we asked how the antidepressant…”
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EIE: Efficient Inference Engine on Compressed Deep Neural Network by Song Han, Xingyu Liu, Huizi Mao, Jing Pu, Pedram, Ardavan, Horowitz, Mark A., Dally, William J.

“…State-of-the-art deep neural networks (DNNs) have hundreds of millions of connections and are both computationally and memory intensive, making them difficult…”
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Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss by Rosen, Clifford J., Horowitz, Mark C.

“…Adipose tissue is a dynamic component of the bone marrow, regulating skeletal remodelling and secreting paracrine and endocrine factors that can affect…”
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Bone Marrow Adipose Tissue Is an Endocrine Organ that Contributes to Increased Circulating Adiponectin during Caloric Restriction by Cawthorn, William P., Scheller, Erica L., Learman, Brian S., Parlee, Sebastian D., Simon, Becky R., Mori, Hiroyuki, Ning, Xiaomin, Bree, Adam J., Schell, Benjamin, Broome, David T., Soliman, Sandra S., DelProposto, Jenifer L., Lumeng, Carey N., Mitra, Aditi, Pandit, Sandeep V., Gallagher, Katherine A., Miller, Joshua D., Krishnan, Venkatesh, Hui, Susanta K., Bredella, Miriam A., Fazeli, Pouneh K., Klibanski, Anne, Horowitz, Mark C., Rosen, Clifford J., MacDougald, Ormond A.

“…The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. Circulating adiponectin increases in lean states such as caloric…”
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The serotonin hypothesis of depression: both long discarded and still supported? by Moncrieff, Joanna, Cooper, Ruth E., Stockmann, Tom, Amendola, Simone, Hengartner, Michael P., Plöderl, Martin, Horowitz, Mark A.

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