Search Results - "Horowitz, E."

Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease by Horowitz, Julie E., Warner, Neil, Staples, Jeffrey, Crowley, Eileen, Gosalia, Nehal, Murchie, Ryan, Van Hout, Cristopher, Fiedler, Karoline, Welch, Gabriel, King, Alejandra Klauer, Reid, Jeffrey G., Overton, John D., Baras, Aris, Shuldiner, Alan R., Griffiths, Anne, Gottesman, Omri, Muise, Aleixo M., Gonzaga-Jauregui, Claudia

“…Inflammatory bowel disease (IBD), clinically defined as Crohn’s disease (CD), ulcerative colitis (UC), or IBD-unclassified, results in chronic inflammation of…”
Get full text

The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps by Bachert, Claus, Hicks, Alexandra, Gane, Simon, Peters, Anju T, Gevaert, Philippe, Nash, Scott, Horowitz, Julie E, Sacks, Harry, Jacob-Nara, Juby A

“…Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses and epithelial…”
Get full text

Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element by Majumder, Kinjal, Koues, Olivia I, Chan, Elizabeth A W, Kyle, Katherine E, Horowitz, Julie E, Yang-Iott, Katherine, Bassing, Craig H, Taniuchi, Ichiro, Krangel, Michael S, Oltz, Eugene M

“…Gene regulation relies on dynamic changes in three-dimensional chromatin conformation, which are shaped by composite regulatory and architectural elements…”
Get full text

Benefit from prolonged dose-intensive chemotherapy for infants with malignant brain tumors is restricted to patients with ependymoma: a report of the Pediatric Oncology Group randomized controlled trial 9233/34 by Strother, Douglas R, Lafay-Cousin, Lucie, Boyett, James M, Burger, Peter, Aronin, Patricia, Constine, Louis, Duffner, Patricia, Kocak, Mehmet, Kun, Larry E, Horowitz, Marc E, Gajjar, Amar

“…The randomized controlled Pediatric Oncology Group study 9233 tested the hypothesis that dose-intensive (DI) chemotherapy would improve event-free survival…”
Get full text

The Vaccine-Hesitant Moment by Horowitz, Mark E., Larson, Heidi J.

“…To the Editor: As a family physician providing Covid-19 vaccination to my patients and to others who have located me through city and national vaccine search…”
Get full text

Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy by Mackall, Crystal L, Fleisher, Thomas A, Brown, Margaret R, Andrich, Mary P, Chen, Clara C, Feuerstein, Irwin M, Horowitz, Marc E, Magrath, Ian T, Shad, Aziza T, Steinberg, Seth M, Wexler, Leonard H, Gress, Ronald E

“…Depletion of CD4+ T lymphocytes is an important clinical problem in bone marrow transplantation 1 – 3 and human immunodeficiency virus (HIV) infection. 4 Yet…”
Get full text

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations by Rowh, M A W, DeMicco, A, Horowitz, J E, Yin, B, Yang-Iott, K S, Fusello, A M, Hobeika, E, Reth, M, Bassing, C H

“…Inactivating Tp53 mutations are frequent genetic lesions in human tumors that harbor genomic instability, including B lineage lymphomas with IG translocations…”
Get full text

Fixed versus flexible GnRH antagonist protocols: who makes the difference? by Weissman, A, Tannus, S, Horowitz, E, Ravhon, A, Barkat, J, Levran, D

Get full text

The autopsy as a performance measure and teaching tool by Horowitz, Richard E., MD, Naritoku, Wesley Y., MD, PhD

“…Summary A survey of pathology training programs about current operations and attitudes revealed that the autopsy is underused in medical student and pathology…”
Get full text

Using a solid-phase variant of enzyme immunoassay for the etiological diagnosis of endogenous uveitis by Kon’kova, A. Yu, Horowitz, E. S., Gavrilova, T. V., Chereshneva, M. V., Afanasievskaya, E. V.

“…Enzyme-linked immunosorbent assay (ELISA) has traditionally been used to diagnose infectious diseases, including ophthalmic ones. As a rule, however,…”
Get full text

Second malignancies after Ewing's sarcoma: radiation dose-dependency of secondary sarcomas by Kuttesch, Jr, J F, Wexler, L H, Marcus, R B, Fairclough, D, Weaver-McClure, L, White, M, Mao, L, Delaney, T F, Pratt, C B, Horowitz, M E, Kun, L E

“…An excess risk of second malignancies has been reported in survivors of Ewing's sarcoma. We examined a multiinstitutional data base to reevaluate the risk…”
Get more information

Postoperative Chemotherapy and Delayed Radiation in Children Less Than Three Years of Age with Malignant Brain Tumors by Duffner, Patricia K, Horowitz, Marc E, Krischer, Jeffrey P, Friedman, Henry S, Burger, Peter C, Cohen, Michael E, Sanford, Robert A, Mulhern, Raymond K, James, Hector E, Freeman, Carolyn R, Seidel, F. Glen, Kun, Larry E

“…The survival of infants and very young children with brain tumors is significantly worse than that of older children, both overall and for specific types of…”
Get full text

The Species Composition of Microbiota and Biological Properties of Dominant Bacterial Species in the Lacrimal Fluid in Patients with Endogenous Uveites by Konkova, A. Yu, Horowitz, E. S., Gavrilova, T. V., Chereshneva, M. V.

“…The purpose : to study the species composition of the lacrimal fluid microbiota in patients with endogenous uveitis and the biological properties of dominant…”
Get full text

Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial by Rabe, Klaus F, Celli, Bartolome R, Wechsler, Michael E, Abdulai, Raolat M, Luo, Xiaodong, Boomsma, Maarten M, Staudinger, Heribert, Horowitz, Julie E, Baras, Aris, Ferreira, Manuel A, Ruddy, Marcella K, Nivens, Michael C, Amin, Nikhil, Weinreich, David M, Yancopoulos, George D, Goulaouic, Helene

“…Genetic data implicate IL-33 in asthma susceptibility. Itepekimab, a monoclonal antibody targeting IL-33, demonstrated clinical activity in asthma, with…”
Get full text

Conventional neuromuscular monitoring versus acceleromyography: it's not the monitor but the anesthetist by Horowitz, Peter E, Gild, William M

Get full text

Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin by Wexler, L H, Andrich, M P, Venzon, D, Berg, S L, Weaver-McClure, L, Chen, C C, Dilsizian, V, Avila, N, Jarosinski, P, Balis, F M, Poplack, D G, Horowitz, M E

“…We conducted an open-label, randomized trial to determine whether ICRF-187 would reduce doxorubicin-induced cardiotoxicity in pediatric sarcoma patients…”
Get more information

Childhood cancer survivor care: development of the Passport for Care by Poplack, David G., Fordis, Michael, Landier, Wendy, Bhatia, Smita, Hudson, Melissa M., Horowitz, Marc E.

“…Numerous calls for improvement in the quality of follow-up care provided to cancer survivors, particularly survivors of childhood cancer have been issued by…”
Get full text

Assessing Hand Perfusion With Eulerian Video Magnification and Waveform Extraction by Rahman, Shihab, Iskandarova, Aygul, Horowitz, Max E, Sanghavi, Kavya K, Aziz, Keith T, Durr, Nicholas, Giladi, Aviram M

“…Timely and accurate triage of upper extremity injuries is critical, but current perfusion monitoring technologies have shortcomings. These limitations are…”
Get full text

Efficacy and Safety of Sarilumab in Hospitalized Patients With Coronavirus Disease 2019: A Randomized Clinical Trial by Sivapalasingam, Sumathi, Lederer, David J, Bhore, Rafia, Hajizadeh, Negin, Criner, Gerard, Hosain, Romana, Mahmood, Adnan, Giannelou, Angeliki, Somersan-Karakaya, Selin, O’Brien, Meagan P, Boyapati, Anita, Parrino, Janie, Musser, Bret J, Labriola-Tompkins, Emily, Ramesh, Divya, Purcell, Lisa A, Gulabani, Daya, Kampman, Wendy, Waldron, Alpana, Ng Gong, Michelle, Saggar, Suraj, Sperber, Steven J, Menon, Vidya, Stein, David K, Sobieszczyk, Magdalena E, Park, William, Aberg, Judith A, Brown, Samuel M, Kosmicki, Jack A, Horowitz, Julie E, Ferreira, Manuel A, Baras, Aris, Kowal, Bari, Thomas DiCioccio, A, Akinlade, Bolanle, Nivens, Michael C, Braunstein, Ned, Herman, Gary A, Yancopoulos, George D, Weinreich, David M

“…Abstract Background Open-label platform trials and a prospective meta-analysis suggest efficacy of anti–interleukin (IL)-6R therapies in hospitalized patients…”
Get full text

Does FEV1/FVC Correlate with Asthma Severity Score in Monitoring Asthma Control? by Foster, C.N, Rafaels, N.M., MS, Tsai, Y.J., MD, Murray, T., MS, Stockton-Porter, M., MS, Horowitz, E., BS, Watson, H., MD, Barnes, K.C., MD

“…The 2007 edition of the National Heart, Lung, and Blood's Expert Panel Report 3 recently added FEV1/FVC as a lung function parameter for monitoring asthma…”
Get full text