Search Results - "Horowitz, Burton"

Altered properties of volume-sensitive osmolyte and anion channels (VSOACs) and membrane protein expression in cardiac and smooth muscle myocytes from Clcn3-/- mice by Yamamoto‐Mizuma, Shintaro, Wang, Ge‐Xin, Liu, Luis L., Schegg, Kathleen, Hatton, William J., Duan, Dayue, Horowitz, Burton, Lamb, Fred S., Hume, Joseph R.

“…ClC-3, a member of the large superfamily of ClC voltage-dependent Cl – channels, has been proposed as a molecular candidate responsible for volume-sensitive…”
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Tamoxifen Activates Smooth Muscle BK Channels through the Regulatory β1 Subunit by Dick, Gregory M., Rossow, Charles F., Smirnov, Sergey, Horowitz, Burton, Sanders, Kenton M.

“…Estrogen (17β-estradiol; 17βE) and xenoestrogens, estrogenic compounds that are not steroid hormones, have non-genomic actions at plasma membrane receptors…”
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Differential expression and alternative splicing of TRP channel genes in smooth muscles by Walker, R L, Hume, J R, Horowitz, B

“…Nonselective cation channels (NSCC) are targets of excitatory agonists in smooth muscle, representing the nonselective cation current I(cat). Na(+) influx…”
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Anion Transport in Heart by Hume, Joseph R, Duan, Dayue, Collier, Mei Lin, Yamazaki, Jun, Horowitz, Burton

“…Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada Hume, Joseph R., Dayue Duan, Mei Lin Collier, Jun Yamazaki,…”
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Cellular and molecular basis for electrical rhythmicity in gastrointestinal muscles by Horowitz, B, Ward, S M, Sanders, K M

“…Regulation of gastrointestinal (GI) motility is intimately coordinated with the modulation of ionic conductance expressed in GI smooth muscle and nonmuscle…”
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TRPC4 currents have properties similar to the pacemaker current in interstitial cells of Cajal by Walker, Rebecca L, Koh, Sang Don, Sergeant, Gerard P, Sanders, Kenton M, Horowitz, Burton

“…Interstitial cells of Cajal (ICC) are the pacemaker cells responsible for the generation and propagation of electrical slow waves in phasic muscles of the…”
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Molecular markers expressed in cultured and freshly isolated interstitial cells of Cajal by Epperson, A, Hatton, W J, Callaghan, B, Doherty, P, Walker, R L, Sanders, K M, Ward, S M, Horowitz, B

“…Located within the tunica muscularis of the gastrointestinal (GI) tract are networks of cells known as interstitial cells of Cajal (ICC). ICC are critical for…”
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Cyclic GMP-dependent Protein Kinase Activates Cloned BKCa Channels Expressed in Mammalian Cells by Direct Phosphorylation at Serine 1072 by Fukao, M, Mason, H S, Britton, F C, Kenyon, J L, Horowitz, B, Keef, K D

“…NO-induced activation of cGMP-dependent protein kinase (PKG) increases the open probability of large conductance Ca 2+ -activated K + channels and results in…”
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A serine residue in ClC-3 links phosphorylation-dephosphorylation to chloride channel regulation by cell volume by Duan, D, Cowley, S, Horowitz, B, Hume, J R

“…In many mammalian cells, ClC-3 volume-regulated chloride channels maintain a variety of normal cellular functions during osmotic perturbation. The molecular…”
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Functional and molecular identification of ERG channels in murine portal vein myocytes by Ohya, Susumu, Horowitz, Burton, Greenwood, Iain A

“…Ion channels encoded by ether-à-go-go-related genes (ERG) have been implicated in repolarization of the cardiac action potential and also as components of the…”
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Comparison of the properties of CLCA1 generated currents and ICl(Ca) in murine portal vein smooth muscle cells by Britton, Fiona C., Ohya, Susumu, Horowitz, Burton, Greenwood, Iain A.

“…Calcium-activated chloride currents ( I Cl(Ca) ) have been recorded in various smooth muscle cells but, to date, there has been no information as to the…”
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Functional and molecular expression of volume-regulated chloride channels in canine vascular smooth muscle cells by Yamazaki, Jun, Duan, Dayue, Janiak, Robert, Kuenzli, Karri, Horowitz, Burton, Hume, Joseph R.

“…We examined the possibility of functional and molecular expression of volume-regulated Cl − channels in vascular smooth muscle using the whole-cell…”
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Development of interstitial cells of Cajal and pacemaking in mice lacking enteric nerves by Ward, Sean M., Ördög, Tamas, Bayguinov, Julia R., Horowitz, Burton, Epperson, Ann, Shen, Liya, Westphal, Heiner, Sanders, Kenton M.

“…Background & Aims: Development of interstitial cells of Cajal (ICC) requires signaling via Kit receptors. Kit is activated by stem cell factor (SCF), but the…”
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Nucleotide regulation of the voltage-dependent nonselective cation conductance in murine colonic myocytes by Monaghan, Kevin P, Koh, Sang Don, Ro, Seungil, Yeom, Jonghun, Horowitz, Burton, Sanders, Kenton M

“…ATP is proposed to be a major inhibitory neurotransmitter in the gastrointestinal (GI) tract, causing hyperpolarization and smooth muscle relaxation. ATP…”
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Differential transcriptional expression of Ca2+ BP superfamilies in murine gastrointestinal smooth muscles by Ohya, Susumu, Horowitz, Burton

“…Calmodulin (Cal) plays important roles for contractile activity in smooth muscles. Recently, two distinct Ca(2+)-binding protein superfamilies with sequence…”
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Functional inhibition of native volume-sensitive outwardly rectifying anion channels in muscle cells and Xenopus oocytes by anti-ClC-3 antibody by Duan, Dayue, Zhong, Juming, Hermoso, Marcela, Satterwhite, Christina M., Rossow, Charles F., Hatton, William J., Ilia Yamboliev, Horowitz, Burton, Hume, Joseph R.

“…Intracellular dialysis of NIH/3T3 cells with a commercially available anti-ClC-3 polyclonal antibody (Ab) for ≈30 min completely inhibited expressed…”
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Functional Characterization of Novel Alternatively Spliced ClC-2 Chloride Channel Variants in the Heart by Britton, Fiona C, Wang, Guan-Lei, Huang, Z Maggie, Ye, Linda, Horowitz, Burton, Hume, Joseph R, Duan, Dayue

“…A novel volume-regulated hyperpolarization-activated chloride inward rectifier channel (Cl.ir) was identified in mammalian heart. To investigate whether ClC-2…”
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Constitutive expression and function of cyclooxygenase-2 in murine gastric muscles by Porcher, Christophe, Horowitz, Burton, Bayguinov, Orline, Ward, Sean M., Sanders, Kenton M.

“…Cyclooxygenase enzymes (COX) generate intermediates in the prostaglandin (PG) cascade. COX-1 is constitutively expressed in many cells, and COX-2 is typically…”
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A Novel Anionic Inward Rectifier in Native Cardiac Myocytes by Duan, Dayue, Ye, Lingyu, Britton, Fiona, Horowitz, Burton, Hume, Joseph R

“…ABSTRACTAlthough the cationic inward rectifiers (Kir and hyperpolarization-activated If channels) have been well characterized in cardiac myocytes, the…”
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ERG K+ channels modulate the electrical and contractile activities of gallbladder smooth muscle by Parr, Edward, Pozo, Maria J, Horowitz, Burton, Nelson, Mark T, Mawe, Gary M

“…The current study was undertaken to test the existence and possible role of ether-a-go-go-related gene 1 (ERG1) protein K(+) channels in gallbladder smooth…”
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