Search Results - "HornyÁk, J"
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DI-083 Benchmarking antibiotic use, cost and nosocomial infection prevalence in surgical and neurosurgical wards–limitations of recent methods to risk adjust patient casemix
Published in European journal of hospital pharmacy. Science and practice (01-03-2016)“…BackgroundAntimicrobial stewardship guidelines emphasise the importance of benchmarking hospital antimicrobial drug use in order to improve patient outcomes…”
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EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression
Published in Molecular cancer research (01-04-2011)“…Polycomb group (PcG) proteins such as Enhancer of zeste homolog 2 (EZH2) are epigenetic transcriptional repressors that function through recognition and…”
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3
A direct link between MITF, innate immunity, and hair graying
Published in PLoS biology (03-05-2018)“…Melanocyte stem cells (McSCs) and mouse models of hair graying serve as useful systems to uncover mechanisms involved in stem cell self-renewal and the…”
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17-AAG inhibits vemurafenib-associated MAP kinase activation and is synergistic with cellular immunotherapy in a murine melanoma model
Published in PloS one (26-02-2018)“…Heat shock protein 90 (HSP90) is a molecular chaperone which stabilizes client proteins with important roles in tumor growth…”
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Diurnal cortisol and obesity in adolescents with and without Down syndrome
Published in Journal of intellectual disability research (01-12-2019)“…Background The prevalence of obesity in adolescents with Down syndrome (DS) far exceeds that in the general population. Cortisol, an adrenal hormone, can be…”
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High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients
Published in Pigment cell and melanoma research (01-05-2014)“…Summary We examined nevi and melanomas in 10 xeroderma pigmentosum (XP) patients with defective DNA repair. The lesions had a lentiginous appearance with…”
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Melanocytic Nevi and the Genetic and Epigenetic Control of Oncogene-Induced Senescence
Published in Dermatologic clinics (01-01-2017)“…Melanocytic nevi represent benign clonal proliferations of the melanocytes in the skin that usually remain stable in size and behavior or disappear during…”
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Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2009)“…To look for a direct role of ultraviolet radiation (UV) exposure in cutaneous melanoma induction, we studied xeroderma pigmentosum (XP) patients who have…”
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Approaches to Managing Changes and Uncertainties in Manufacturing
Published in CIRP annals (1998)“…Today's complex manufacturing systems operate in a changing environment rife with uncertainty. The performance of manufacturing companies ultimately hinges on…”
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The effect of dynamic versus isometric resistance training on pain and functioning among adults with osteoarthritis of the knee
Published in Archives of physical medicine and rehabilitation (01-09-2002)“…Topp R, Woolley S, Hornyak J III, Khuder S, Kahaleh B. The effect of dynamic versus isometric resistance training on pain and functioning among adults with…”
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Neurofibromin as a regulator of melanocyte development and differentiation
Published in Journal of cell science (15-01-2008)“…Patients with the genetic disease type I neurofibromatosis (NF1) exhibit characteristic pigmentary lesions associated with loss of a single allele of NF1,…”
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Multistrategy learning approaches to generate and tune fuzzy control structures and their application in manufacturing
Published in Journal of intelligent manufacturing (01-08-1998)“…Intelligence is strongly connected with learning adapting abilities, therefore such capabilities are considered as indispensable features of intelligent…”
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Next Time, Save Mushrooms for the Pizza
Published in Journal of investigative dermatology (01-07-2018)“…Mann et al. (2018) use recombinant human tyrosinase to screen for novel inhibitors of pigmentation. They develop thiamidol, a new thiazolyl-resorcinol…”
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B6‐Dct‐H2BGFP bitransgenic mice: A standardized mouse model for in vivo characterization of melanocyte development and stem cell differentiation
Published in Pigment cell and melanoma research (01-09-2021)“…Melanocyte stem cells (McSCs) are key components of the hair follicle (HF) stem cell system that regenerate differentiated melanocytes during successive HF…”
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Enhanced mitochondrial sensitivity to creatine in rats bred for high aerobic capacity
Published in Journal of applied physiology (1985) (01-06-2006)“…1 Physiology Division, Department of Medicine, University of California-San Diego, La Jolla; 2 Department of Kinesiology, California State University…”
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SKI knockdown inhibits human melanoma tumor growth in vivo
Published in Pigment cell and melanoma research (01-12-2009)“…Summary The SKI protein represses the TGF‐β tumor suppressor pathway by associating with the Smad transcription factors. SKI is upregulated in human malignant…”
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Pilot Study of ONCOS-102 and Pembrolizumab: Remodeling of the Tumor Microenvironment and Clinical Outcomes in Anti-PD-1-Resistant Advanced Melanoma
Published in Clinical cancer research (04-01-2023)“…Intratumoral oncolytic virotherapy may overcome anti-PD(L)-1 resistance by triggering pro-inflammatory remodeling of the tumor microenvironment. This pilot…”
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Dopachrome tautomerase ( Dct) regulates neural progenitor cell proliferation
Published in Developmental biology (15-08-2006)“…DOPAchrome tautomerase (Dct) functions downstream of tyrosinase in the biosynthetic pathway of eumelanin by catalyzing the conversion of dopachrome to…”
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Cellular Phenotypic Plasticity of Cutaneous Melanoma: A Complex Puzzle
Published in Journal of investigative dermatology (01-04-2020)“…Wenzina et al. (2020) explore the potential role of E-cadherin (CDH1) as a marker for invasive behavior in melanoma. The authors show that CDH1 expression is…”
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Skin cancers, blindness, and anterior tongue mass in African brothers
Published in Journal of the American Academy of Dermatology (01-11-2008)Get full text
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