Search Results - "Horng, Howard"

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers by Yee, Sook Wah, Giacomini, Marilyn M., Shen, Hong, Humphreys, W. Griffith, Horng, Howard, Brian, William, Lai, Yurong, Kroetz, Deanna L., Giacomini, Kathleen M.

“…Understanding transporter‐mediated drug–drug interactions is an integral part of risk assessment in drug development. Recent studies support the use of…”
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The nonenzymatic reactivity of the acyl-linked metabolites of mefenamic acid toward amino and thiol functional group bionucleophiles by Horng, Howard, Benet, Leslie Z

“…Mefenamic acid (MFA), a carboxylic acid-containing nonsteroidal anti-inflammatory drug, is metabolized into the chemically-reactive MFA-1-O-acyl-glucuronide…”
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Characterization of the Acyl-Adenylate Linked Metabolite of Mefenamic Acid by Horng, Howard, Benet, Leslie Z

“…Mefenamic acid, (MFA), a carboxylic acid-containing nonsteroidal anti-inflammatory drug (NSAID), is metabolized into the chemically reactive conjugates…”
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Association of age, baseline kidney function, and medication exposure with declines in creatinine clearance on pre-exposure prophylaxis: an observational cohort study by Gandhi, Monica, Dr Prof, Glidden, David V, Prof, Mayer, Kenneth, Prof, Schechter, Mauro, Prof, Buchbinder, Susan, Prof, Grinsztejn, Beatriz, MD, Hosek, Sybil, PhD, Casapia, Martin, MD, Guanira, Juan, MD, Bekker, Linda-Gail, Prof, Louie, Alexander, BA, Horng, Howard, PhD, Benet, Leslie Z, Prof, Liu, Albert, MD, Grant, Robert M, Prof

“…Summary Background As pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine for the prevention of HIV infection is rolled out…”
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Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose by Vo, Kathy T., MD, Horng, Howard, PhD, Smollin, Craig G., MD, Benowitz, Neal L., MD

“…Abstract Background Carisoprodol, a centrally acting muscle relaxant with a high abuse potential, has barbiturate-like properties at the GABA-A receptor,…”
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Newly Acquired Infection With Multidrug-Resistant HIV-1 in a Patient Adherent to Preexposure Prophylaxis by Markowitz, Martin, Grossman, Howard, Anderson, Peter L, Grant, Robert, Gandhi, Monica, Horng, Howard, Mohri, Hiroshi

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Prolonged toxicity from Kambo cleansing ritual by Li, Kai, Horng, Howard, Lynch, Kara, Smollin, Craig G.

“…Context: Kambo cleanse is a purification, cleansing ritual traditionally performed by South American shaman to confer luck and health to hunters. Case details:…”
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Comparison of Measures of Adherence to Human Immunodeficiency Virus Preexposure Prophylaxis Among Adolescent and Young Men Who Have Sex With Men in the United States by Koss, Catherine A, Hosek, Sybil G, Bacchetti, Peter, Anderson, Peter L, Liu, Albert Y, Horng, Howard, Benet, Leslie Z, Kuncze, Karen, Louie, Alexander, Saberi, Parya, Wilson, Craig M, Gandhi, Monica

“…Young men-who-have-sex-with-men (MSM) are disproportionately impacted by human immunodeficiency virus (HIV). Preexposure prophylaxis (PrEP) could reduce HIV…”
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Cannabis Intoxication Case Series: The Dangers of Edibles Containing Tetrahydrocannabinol by Vo, Kathy T., Horng, Howard, Li, Kai, Ho, Raymond Y., Wu, Alan H.B., Lynch, Kara L., Smollin, Craig G.

“…Cannabis and its principal active constituent, Δ9-tetrahydrocannabinol (THC), are increasingly available as edibles resembling commercially available food…”
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Hair levels of preexposure prophylaxis drugs measure adherence and are associated with renal decline among men/transwomen by Gandhi, Monica, Murnane, Pamela M, Bacchetti, Peter, Elion, Richard, Kolber, Michael A, Cohen, Stephanie E, Horng, Howard, Louie, Alexander, Kuncze, Karen, Koss, Catherine A, Anderson, Peter L, Buchbinder, Susan, Liu, Albert

“…The US preexposure prophylaxis (PrEP) Demonstration Project (U.S. Demo) evaluated MSM on PrEP postmarketing and found low seroconversion rates. The objective…”
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Strong Correlation Between Concentrations of Tenofovir (TFV) Emtricitabine (FTC) in Hair and TFV Diphosphate and FTC Triphosphate in Dried Blood Spots in the iPrEx Open Label Extension: Implications for Pre-exposure Prophylaxis Adherence Monitoring by Gandhi, Monica, Glidden, David V., Liu, Albert, Anderson, Peter L., Horng, Howard, Defechereux, Patricia, Guanira, Juan V., Grinsztejn, Beatriz, Chariyalertsak, Suwat, Bekker, Linda-Gail, Grant, Robert M.

“…Self-reported adherence to pre-exposure prophylaxis (PrEP) has limitations, raising interest in pharmacologie monitoring. Drug concentrations in hair and dried…”
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Fatal Taxus baccata ingestion with perimortem serum taxine B quantification by Arens, Ann M., Anaebere, Tiffany C., Horng, Howard, Olson, Kent

“…Introduction: Common yew (Taxus baccata) is a common decorative evergreen shrub with potentially fatal toxicity hallmarked by seizure, arrhythmia and…”
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Antiretroviral Concentrations in Hair Strongly Predict Virologic Response in a Large Human Immunodeficiency Virus Treatment-naive Clinical Trial by Gandhi, Monica, Bacchetti, Peter, Ofokotun, Igho, Jin, Chengshi, Ribaudo, Heather J, Haas, David W, Sheth, Anandi N, Horng, Howard, Phung, Nhi, Kuncze, Karen, Okochi, Hideaki, Landovitz, Raphael J, Lennox, Jeffrey, Currier, Judith S

“…Abstract Concentrations of antiretrovirals in hair are associated with virologic outcomes in cohorts of human immunodeficiency virus (HIV)-positive individuals…”
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Newly Acquired Infection with Multi-Drug Resistant HIV-1 in a Patient Adherent to Pre-Exposure Prophylaxis by Markowitz, Martin, Grossman, Howard, Anderson, Peter L., Grant, Robert, Gandhi, Monica, Horng, Howard, Mohri, Hiroshi

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Defining a Cutoff for Atazanavir in Hair Samples Associated With Virological Failure Among Adolescents Failing Second-Line Antiretroviral Treatment by Chawana, Tariro D, Gandhi, Monica, Nathoo, Kusum, Ngara, Bernard, Louie, Alexander, Horng, Howard, Katzenstein, David, Metcalfe, John, Nhachi, Charles F B

“…Adequate antiretroviral exposure is crucial to virological suppression. We assessed the relationship between atazanavir hair levels with self-reported…”
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Hair concentrations of antiretrovirals predict viral suppression in HIV-infected pregnant and breastfeeding Ugandan women by Koss, Catherine A, Natureeba, Paul, Mwesigwa, Julia, Cohan, Deborah, Nzarubara, Bridget, Bacchetti, Peter, Horng, Howard, Clark, Tamara D, Plenty, Albert, Ruel, Theodore D, Achan, Jane, Charlebois, Edwin D, Kamya, Moses R, Havlir, Diane V, Gandhi, Monica

“…Hair concentrations are a noninvasive measure of cumulative antiretroviral exposure and the strongest predictor of viral suppression in large cohorts of…”
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Newly Acquired Infection with Multi-Drug Resistant HIV-1 in a Patient Adherent to Pre-Exposure Prophylaxis by Markowitz, Martin, Grossman, Howard, Anderson, Peter L, Grant, Robert, Gandhi, Monica, Horng, Howard, Mohri, Hiroshi

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Brief Report: Adherence Biomarker Measurements in Older and Younger HIV-Infected Adults Receiving Tenofovir-Based Therapy by Seifert, Sharon M, Castillo-Mancilla, Jose R, Erlandson, Kristine, Morrow, Mary, Gandhi, Monica, Kuncze, Karen, Horng, Howard, Zheng, Jia-Hua, Bushman, Lane R, Kiser, Jennifer J, MaWhinney, Samantha, Anderson, Peter L

“…Concentrations of tenofovir (TFV) in hair and tenofovir diphosphate (TFV-DP) in dried blood spots (DBSs) as measures of cumulative exposure have been primarily…”
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Adherence biomarker measurements in older and younger HIV-infected adults receiving tenofovir-based therapy by Seifert, Sharon M, Castillo-Mancilla, Jose R, Erlandson, Kristine, Morrow, Mary, Gandhi, Monica, Kuncze, Karen, Horng, Howard, Zheng, Jia-Hua, Bushman, Lane R, Kiser, Jennifer J, MaWhinney, Samantha, Anderson, Peter L

“…BACKGROUND:Concentrations of tenofovir (TFV) in hair and TFV-diphosphate (TFV-DP) in dried blood spots (DBS) as measures of cumulative exposure have been…”
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Rapid respiratory arrest after ingestion of poison hemlock mistaken for wild celery by Chen, Hsien-Yi, Horng, Howard, Rowley, Freda, Smollin, Craig

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