Search Results - "Hornef, M."

Does a prenatal bacterial microbiota exist? by Hornef, M, Penders, J

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Bile acids drive the newborn’s gut microbiota maturation by van Best, N., Rolle-Kampczyk, U., Schaap, F. G., Basic, M., Olde Damink, S. W. M., Bleich, A., Savelkoul, P. H. M., von Bergen, M., Penders, J., Hornef, M. W.

“…Following birth, the neonatal intestine is exposed to maternal and environmental bacteria that successively form a dense and highly dynamic intestinal…”
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Neonatal mucosal immunology by Torow, N, Marsland, B J, Hornef, M W, Gollwitzer, E S

“…Although largely deprived from exogenous stimuli in utero , the mucosal barriers of the neonate after birth are bombarded by environmental, nutritional, and…”
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Secreted enteric antimicrobial activity localises to the mucus surface layer by Meyer-Hoffert, U, Hornef, M W, Henriques-Normark, B, Axelsson, L-G, Midtvedt, T, Pütsep, K, Andersson, M

“…The intestinal mucosa is constantly exposed to a dense and highly dynamic microbial flora and challenged by a variety of enteropathogenic bacteria…”
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c-Jun N-terminal kinase 2 promotes enterocyte survival and goblet cell differentiation in the inflamed intestine by Mandić, A D, Bennek, E, Verdier, J, Zhang, K, Roubrocks, S, Davis, R J, Denecke, B, Gassler, N, Streetz, K, Kel, A, Hornef, M, Cubero, F J, Trautwein, C, Sellge, G

“…c-Jun N-terminal kinases (JNKs) contribute to immune signaling but their functional role during intestinal mucosal inflammation has remained ill defined. Using…”
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Dedicated immunosensing of the mouse intestinal epithelium facilitated by a pair of genetically coupled lectin-like receptors by Leibelt, S, Friede, M E, Rohe, C, Gütle, D, Rutkowski, E, Weigert, A, Kveberg, L, Vaage, J T, Hornef, M W, Steinle, A

“…The integrity of the intestinal epithelium is constantly surveyed by a peculiar subset of innate-like T lymphocytes embedded in the epithelial cell layer,…”
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Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes by Duerr, C U, Salzman, N H, Dupont, A, Szabo, A, Normark, B H, Normark, S, Locksley, R M, Mellroth, P, Hornef, M W

“…Innate immune recognition of the bacterial cell wall constituent peptidoglycan by the cytosolic nucleotide-binding oligomerization domain 2 (Nod2) receptor has…”
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Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells by Hornef, Mathias W, Normark, Birgitta Henriques, Vandewalle, Alain, Normark, Staffan

“…Toll-like receptor (TLR)4 has recently been shown to reside in the Golgi apparatus of intestinal crypt epithelial m-ICcl2 cells, colocalizing with internalized…”
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Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells by Hornef, Mathias W, Frisan, Teresa, Vandewalle, Alain, Normark, Staffan, Richter-Dahlfors, Agneta

“…Toll-like receptor (TLR) 4 is mainly found on cells of the myelopoietic lineage. It recognizes lipopolysaccharide (LPS) and mediates cellular activation and…”
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Bacterial strategies for overcoming host innate and adaptive immune responses by Normark, Staffan, Hornef, Mathias W, Wick, Mary Jo, Rhen, Mikael

“…In higher organisms a variety of host defense mechanisms control the resident microflora and, in most cases, effectively prevent invasive microbial disease…”
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Coincidence of Epstein-Barr virus reactivation, cytomegalovirus infection, and rejection episodes in renal transplant recipients by Hornef, M W, Bein, G, Fricke, L, Steinhoff, J, Wagner, H J, Hinderer, W, Sonneborn, H H, Kirchner, H

“…Reactivation of the Epstein-Barr virus was reported to occur frequently under immunosuppressive therapy following organ transplantation. However, little is…”
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The function and biological role of toll-like receptors in infectious diseases: an update by Hornef, Mathias W, Henriques-Normark, Birgitta, Normark, Staffan

“…PURPOSE OF REVIEWThe present review summarizes exciting new findings and reports recent advances in the understanding of the role of toll-like receptors in…”
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Lytic replication of Epstein-Barr virus in the peripheral blood: Analysis of viral gene expression in B lymphocytes during infectious mononucleosis and in the normal carrier state by PRANG, N. S, HORNEF, M. W, JÄGER, M, WAGNER, H. J, WOLF, H, SCHWARZMANN, F. M

“…Epstein-Barr virus (EBV) has been shown to establish latency in resting B lymphocytes of the peripheral blood. This creates a virus reservoir in contrast to…”
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Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition by Fulde, Marcus, Sommer, Felix, Chassaing, Benoit, van Vorst, Kira, Dupont, Aline, Hensel, Michael, Basic, Marijana, Klopfleisch, Robert, Rosenstiel, Philip, Bleich, André, Bäckhed, Fredrik, Gewirtz, Andrew T., Hornef, Mathias W.

“…Alterations in enteric microbiota are associated with several highly prevalent immune-mediated and metabolic diseases 1 – 3 , and experiments involving faecal…”
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Comparison of MB/BacT and BACTEC 460 TB Systems for Recovery of Mycobacteria in a Routine Diagnostic Laboratory by ROGGENKAMP, A, HORNEF, M. W, MASCH, A, AIGNER, B, AUTENRIETH, I. B, HEESEMANN, J

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How neutrophils recognize bacteria and move toward infection by Normark, Staffan, Henriques Normark, Birgitta, Hornef, Mathias

“…The finding that CD38 mediates a sustained calcium signal inside neutrophils, which directs their movement toward lung tissue infected with pneumococcus…”
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Thyrotoxicosis Induced by Thyroid Involvement of Disseminated Aspergillus fumigatus Infection by HORNEF, M. W, SCHOPOHL, J, ZIETZ, C, HALLFELDT, K. K. J, ROGGENKAMP, A, GÄRTNER, R, HEESEMANN, J

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Significance of cytoplasmic staining in the cytomegalovirus pp65 antigen test by HORNEF, M. W, HACKSTEIN, H, KIRCHNER, H, BEIN, G

“…Immunostaining of the cytomegalovirus (CMV) pp65 antigen in the nucleus of peripheral blood leukocytes is a highly specific tool for diagnosis of active CMV…”
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Cytokine production in a whole-blood assay after Epstein-Barr virus infection in vivo by Hornef, M W, Wagner, H J, Kruse, A, Kirchner, H

“…Epstein-Barr virus (EBV) has a marked tropism for cells of the immune system, and infection can result in profound immunomodulatory effects. In order to…”
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Humoral response in a patient with cutaneous nocardiosis by Hornef, M W, Gandorfer, A, Heesemann, J, Roggenkamp, A

“…The clinical appearance of infection due to Nocardia spp. varies widely. The low sensitivity of direct microscopy and the slow growth of the organism challenge…”
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