Search Results - "Horne, M K"

Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae) by Nuckols, J. T., Huang, Y.-J. S., Higgs, S., Miller, A. L., Pyles, R. B., Spratt, H. M., Horne, K. M., Vanlandingham, D. L.

“…The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric…”
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Timecourse of striatal re-innervation following lesions of dopaminergic SNpc neurons of the rat by Stanic, D., Finkelstein, D. I., Bourke, D. W., Drago, J., Horne, M. K.

“…Previously we described the extent of sprouting that axons of the rat substantia nigra pars compacta (SNpc) undergo to grow new synapses and re‐innervate the…”
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Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury by Nisbet, D. R., Moses, D., Gengenbach, T. R., Forsythe, J. S., Finkelstein, D. I., Horne, M. K.

“…In this study, thermoresponsive xyloglucan hydrogel scaffolds were investigated as candidates for neural tissue engineering of the spinal cord. The hydrogels…”
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Clinical Trial of Induced Hypothermia in Comatose Survivors of Out-of-Hospital Cardiac Arrest by Bernard, Stephen A, Jones, Bruce Mac C, Horne, Malcolm K

“…Study objective: To examine the effects of moderate hypothermia (33 ° C), induced by surface cooling in the ED and maintained for 12 hours in the ICU, on…”
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Axonal sprouting following lesions of the rat substantia nigra by Finkelstein, D.I., Stanic, D., Parish, C.L., Tomas, D., Dickson, K., Horne, M.K.

“…Parkinson's disease is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Symptoms do not appear until most…”
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The Role of Dopamine Receptors in Regulating the Size of Axonal Arbors by Parish, C. L, Finkelstein, D. I, Drago, J, Borrelli, E, Horne, M. K

“…Factors that regulate terminal arbor size of substantia nigra pars compacta (SNpc) neurons during development and after injury are not well understood. This…”
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Fetal striatum- and ventral mesencephalon–derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo by Moses, D, Drago, J, Teper, Y, Gantois, I, Finkelstein, D.I, Horne, M.K

“…Abstract The pathogenesis of Parkinson's disease (PD) involves ongoing apoptotic loss of dopaminergic neurons in the substantia nigra pars compacta. Local…”
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Heparin‐induced thrombocytopenia (HIT) due to heparin flushes: a report of three cases by Kadidal, V. V., Mayo, D. J., Horne, M. K.

“… Kadidal VV, Mayo DJ, Horne MK (National Institutes of Health, Bethesda, MD 20892, USA) Heparin‐induced thrombocytopenia (HIT) due to heparin flushes: a…”
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The effect of surface hydrophilicity on the behavior of embryonic cortical neurons by Nisbet, D.R., Pattanawong, S., Nunan, J., Shen, W., Horne, M.K., Finkelstein, D.I., Forsythe, J.S.

“…The aim of this study was to investigate the interaction of mouse embryonic cortical neurons on P LLA and PLGA substrates, which were partially hydrolysed…”
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Morphology and gelation of thermosensitive chitosan hydrogels by Crompton, K.E., Prankerd, R.J., Paganin, D.M., Scott, T.F., Horne, M.K., Finkelstein, D.I., Gross, K.A., Forsythe, J.S.

“…The morphology of physical hydrogels is often difficult to examine due to the delicate nature of the system and therefore has not been studied in detail…”
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Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc by Stanic, D., Parish, C. L., Zhu, W. M., Krstew, E. V., Lawrence, A. J., Drago, J., Finkelstein, D. I., Horne, M. K.

“…Following partial substantia nigra lesions, remaining dopaminergic neurones sprout, returning terminal density in the dorsal striatum to normal by 16 weeks…”
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Proteomic analysis of platelet α‐granules using mass spectrometry by MAYNARD, D. M., HEIJNEN, H. F. G., HORNE, M. K., WHITE, J. G., GAHL, W. A.

“…Background: Platelets have three major types of secretory organelles: lysosomes, dense granules, and α‐granules. α‐Granules contain several adhesive proteins…”
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Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease by Butcher, N J, Horne, M K, Mellick, G D, Fowler, C J, Masters, C L, Minchin, R F

“…The cytosolic aryl sulfotransferase genes SULT1A3 and SULT1A4 are located on chromosome 16p11.2 in a region of chromosomal instability. SULT1A3/4 are important…”
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Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice by Drago, J, McColl, C D, Horne, M K, Finkelstein, D I, Ross, S A

“…Neuronal nicotinic acetylcholine receptors are ligand-gated ion channels that subserve a range of functions in the brain and peripheral nervous system. They…”
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Polylysine-functionalised thermoresponsive chitosan hydrogel for neural tissue engineering by Crompton, K.E, Goud, J.D, Bellamkonda, R.V, Gengenbach, T.R, Finkelstein, D.I, Horne, M.K, Forsythe, J.S

“…Abstract Foetal mouse cortical cells were cultured on 2D films and within 3D thermally responsive chitosan/glycerophosphate salt (GP) hydrogels. The…”
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Review Paper: A Review of the Cellular Response on Electrospun Nanofibers for Tissue Engineering by Nisbet, D.R., Forsythe, J.S., Shen, W., Finkelstein, D.I., Horne, M.K.

“…Electrospinning has been employed extensively in tissue engineering to generate nanofibrous scaffolds from either natural or synthetic biodegradable polymers…”
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Daytime sleep in Parkinson's disease measured by episodes of immobility by Kotschet, K, Johnson, W, McGregor, S, Kettlewell, J, Kyoong, A, O'Driscoll, D.M, Turton, A.R, Griffiths, R.I, Horne, M.K

“…Abstract Excessive daytime sleepiness (EDS) is common in Parkinson's Disease (PD). Actigraphy uses periods of immobility as surrogate markers of nighttime…”
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Chronic corticotropin‐releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn‐Hooded rats by Lawrence, A. J., Parish, C. L., Chen, F., Lodge, D. J., Krstew, E. V., Card, K., Finkelstein, D. I., Horne, M. K.

“…Corticotropin‐releasing factor is a neuropeptide associated with the integration of physiological and behavioural responses to stress and also in the…”
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Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size by Parish, C. L., Stanic, D., Drago, J., Borrelli, E., Finkelstein, D. I., Horne, M. K.

“…This study demonstrates that pharmacological manipulation of the dopamine (DA) receptors can modulate the size of the axonal tree of substantia nigra pars…”
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A Commentary on the Need for 3D-Biologically Relevant In Vitro Environments to Investigate Astrocytes and Their Role in Central Nervous System Inflammation by Maclean, F. L., Williams, R. J., Horne, M. K., Nisbet, D. R.

“…Astrocytes execute essential functions in the healthy CNS, whilst also being implicated as a limitation to functional regeneration and repair after injury…”
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