Search Results - "Horne, Arik"

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke by Werner, Yves, Mass, Elvira, Ashok Kumar, Praveen, Ulas, Thomas, Händler, Kristian, Horne, Arik, Klee, Kathrin, Lupp, Amelie, Schütz, Dagmar, Saaber, Friederike, Redecker, Christoph, Schultze, Joachim L., Geissmann, Frederic, Stumm, Ralf

“…Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions…”
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Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs by Langkabel, Jan, Horne, Arik, Bonaguro, Lorenzo, Holsten, Lisa, Hesse, Tatiana, Knaus, Alexej, Riedel, Yannick, Becker, Matthias, Händler, Kristian, Elmzzahi, Tarek, Bassler, Kevin, Reusch, Nico, Yeghiazarian, Leon Harootoonovtch, Pecht, Tal, Saglam, Adem, Ulas, Thomas, Aschenbrenner, Anna C., Kaiser, Franziska, Kubaczka, Caroline, Schultze, Joachim L., Schorle, Hubert

“…Blastocyst-derived stem cell lines were shown to self-organize into embryo-like structures in 3D cell culture environments. Here, we provide evidence that…”
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Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state by Carraro, Caterina, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Horne, Arik, Oestreich, Marie, Warnat-Herresthal, Stefanie, Helbing, Tim, De Franco, Michele, Haendler, Kristian, Mukherjee, Sach, Ulas, Thomas, Gandin, Valentina, Goettlich, Richard, Aschenbrenner, Anna C, Schultze, Joachim L, Gatto, Barbara

“…Omics-based technologies are driving major advances in precision medicine, but efforts are still required to consolidate their use in drug discovery. In this…”
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CRELD1 modulates homeostasis of the immune system in mice and humans by Bonaguro, Lorenzo, Köhne, Maren, Schmidleithner, Lisa, Schulte-Schrepping, Jonas, Warnat-Herresthal, Stefanie, Horne, Arik, Kern, Paul, Günther, Patrick, ter Horst, Rob, Jaeger, Martin, Rahmouni, Souad, Georges, Michel, Falk, Christine S., Li, Yang, Mass, Elvira, Beyer, Marc, Joosten, Leo A. B., Netea, Mihai G., Ulas, Thomas, Schultze, Joachim L., Aschenbrenner, Anna C.

“…CRELD1 is a pivotal factor for heart development, the function of which is unknown in adult life. We here provide evidence that CRELD1 is an important…”
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Identification of drug candidates targeting monocyte reprogramming in people living with HIV by Knoll, Rainer, Bonaguro, Lorenzo, Dos Santos, Jéssica C, Warnat-Herresthal, Stefanie, Jacobs-Cleophas, Maartje C P, Blümel, Edda, Reusch, Nico, Horne, Arik, Herbert, Miriam, Nuesch-Germano, Melanie, Otten, Twan, van der Heijden, Wouter A, van de Wijer, Lisa, Shalek, Alex K, Händler, Kristian, Becker, Matthias, Beyer, Marc D, Netea, Mihai G, Joosten, Leo A B, van der Ven, Andre J A M, Schultze, Joachim L, Aschenbrenner, Anna C

“…People living with HIV (PLHIV) are characterized by functional reprogramming of innate immune cells even after long-term antiretroviral therapy (ART). In order…”
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Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia by Eifert, Theresa, Hsu, Chen-Jen, Becker, Alicia L., Graessle, Sarah, Horne, Arik, Bemmann, Franziska, Zhang, Qirui, Heuser, Michael, Vasioukhin, Valeri, Scholl, Sebastian, Hochhaus, Andreas, Siegerist, Florian, Endlich, Nicole, Bullinger, Lars, Lane, Steven W., Haas, Simon, Schnoeder, Tina M., Heidel, Florian H.

“…Scribble complex proteins can influence cell fate decisions and self-renewal capacity of hematopoietic cells. While specific cellular functions of Scribble…”
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Activation of gp130 signaling in T cells drives T H 17-mediated multi-organ autoimmunity by Baumgartner, Francis, Bamopoulos, Stefanos A, Faletti, Laura, Hsiao, Hsiang-Jung, Holz, Maximilian, Gonzalez-Menendez, Irene, Boldo, Llorenç, Horne, Arik, Gosavi, Sanket, Özerdem, Ceren, Singh, Nikita, Liebig, Sven, Ramamoorthy, Senthilkumar, Lehmann, Malte, Demel, Uta, Kühl, Anja A, Wartewig, Tim, Ruland, Jürgen, Wunderlich, Frank T, Schick, Markus, Walther, Wolfgang, Rose-John, Stefan, Haas, Simon, Quintanilla-Martinez, Leticia, Feske, Stefan, Ehl, Stephan, Glauben, Rainer, Keller, Ulrich

“…The IL-6-gp130-STAT3 signaling axis is a major regulator of inflammation. Activating mutations in the gene encoding gp130 and germline gain-of-function…”
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Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease by Kapellos, Theodore S., Baßler, Kevin, Fujii, Wataru, Nalkurthi, Christina, Schaar, Anna C., Bonaguro, Lorenzo, Pecht, Tal, Galvao, Izabela, Agrawal, Shobhit, Saglam, Adem, Dudkin, Erica, Frishberg, Amit, de Domenico, Elena, Horne, Arik, Donovan, Chantal, Kim, Richard Y., Gallego-Ortega, David, Gillett, Tessa E., Ansari, Meshal, Schulte-Schrepping, Jonas, Offermann, Nina, Antignano, Ignazio, Sivri, Burcu, Lu, Wenying, Eapen, Mathew S., van Uelft, Martina, Osei-Sarpong, Collins, van den Berge, Maarten, Donker, Hylke C., Groen, Harry J.M., Sohal, Sukhwinder S., Klein, Johanna, Schreiber, Tina, Feißt, Andreas, Yildirim, Ali Önder, Schiller, Herbert B., Nawijn, Martijn C., Becker, Matthias, Händler, Kristian, Beyer, Marc, Capasso, Melania, Ulas, Thomas, Hasenauer, Jan, Pizarro, Carmen, Theis, Fabian J., Hansbro, Philip M., Skowasch, Dirk, Schultze, Joachim L.

“…Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in…”
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