Search Results - "Horn, Glenn T"

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences by Scharf, Stephen J., Horn, Glenn T., Erlich, Henry A.

“…A method is described for directly cloning enzymatically amplified segments of genomic DNA into an M13 vector for sequence analysis. A 110--base pair fragment…”
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Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase by Saiki, Randall K., Gelfand, David H., Stoffel, Susanne, Scharf, Stephen J., Higuchi, Russell, Horn, Glenn T., Mullis, Kary B., Erlich, Henry A.

“…A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction. The enzyme, isolated from Thermus aquaticus,…”
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Amplification of a hightly polymorphic VNTR segment by the polymerase chain reaction by Horn, Glenn T., Richards, Brenda, Klinger, Katherine W.

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Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes by Saiki, Randall K, Bugawan, Teodorica L, Horn, Glenn T, Mullis, Kary B, Erlich, Henry A

“…Allelic sequence variation has been analysed by synthetic oligonucleotide hybridization probes which can detect single base substitutions in human genomic DNA…”
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Detection by PCR of a VNTR polymorphism at D4S43 by HORN, G. T, MCCLATCHEY, A. I, RICHARDS, B, MACDONALD, M. E, GUSELLA, J. F

“…The anonymous DNA probe pKP1.65 reveals a VNTR polymorphism, detected as a StuI RFLP, within the human D4S43 locus. We have sequenced a 1269 bp PstI fragment…”
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Detection by PCR of the VNTR polymorphism at D4S95 by ALLITTO, B. A, HORN, G. T, ALTHEN, M. R, RICHARDS, B, MCCLATCHEY, A. I, WASMUTH, J. J, GUSELLA, J. F

“…Images…”
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Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia by Saiki, Randall K., Scharf, Stephen, Faloona, Fred, Mullis, Kary B., Horn, Glenn T., Erlich, Henry A., Arnheim, Norman

“…Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first involves the primer-mediated…”
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Allelic Sequence Variation of the HLA-DQ Loci: Relationship to Serology and to Insulin-Dependent Diabetes Susceptibility by Horn, Glenn T., Bugawan, Teodorica L., Long, Christopher M., Erlich, Henry A.

“…Analysis of sequence variation in the polymorphic second exon of the major histocompatibility complex genes HLA-DQα and -DQβ has revealed 8 allelic variants at…”
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Characterization and rapid diagnostic analysis of DNA polymorphisms closely linked to the cystic fibrosis locus by Horn, G T, Richards, B, Merrill, J J, Klinger, K W

“…Six genetic polymorphisms, closely linked to the cystic fibrosis gene and useful in clinical linkage analysis, have been characterized and converted to a more…”
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Sequence analysis of HLA class II genes from insulin-dependent diabetic individuals by Horn, G T, Bugawan, T L, Long, C M, Manos, M M, Erlich, H A

“…To examine the nature of HLA-linked genetic susceptibility to insulin-dependent diabetes mellitus (IDDM), we compared HLA class II gene sequences from IDDM…”
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Characterization and rapid analysis of the highly polymorphic VNTR locus D4S125 (YNZ32), closely linked to the Huntington disease gene by Richards, B, Horn, G T, Merrill, J J, Klinger, K W

“…The highly polymorphic VNTR locus pYNZ32 has been more extensively characterized, and its analysis converted to a rapid PCR-based format. DNA sequencing in the…”
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Cystic fibrosis mutations in North American populations of french ancestry : analysis of Quebec French-Canadian and Louisiana Acadian families by ROZEN, R, SCHWARTZ, R. H, FUJIWARA, T. M, MORGAN, K, HILMAN, B. C, STANISLOVITIS, P, HORN, G. T, KLINGER, K, DAIGNEAULT, J, DE BRAEKELEER, M, KEREM, B.-S, LAP-CHEE TSUI

“…A 3-bp deletion (delta F508) in the cystic fibrosis (CF) gene is the mutation on the majority of CF chromosomes. We studied 112 CF families from North American…”
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Cystic fibrosis mutations in the Hutterite Brethren by Klinger, K, Horn, G T, Stanislovitis, P, Schwartz, R H, Fujiwara, T M, Morgan, K

“…The presence or absence of the major cystic fibrosis (CF) mutation, delta F508, in the general patient population was determined by Kerem et al. using…”
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Shared molecular markers of genetic predisposition to seropositive rheumatoid arthritis by Morel, P A, Horn, G T, Budd, R C, Erlich, H A, Fathman, C G

“…Rheumatoid arthritis is associated with the human class II major histocompatibility complex antigens known as HLA-DR4. HLA-DR4 can be subdivided by cellular…”
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