Search Results - "Horlock, P. L."

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    Quantitative measurement of blood-brain barrier permeability using rubidium-82 and positron emission tomography by Brooks, D J, Beaney, R P, Lammertsma, A A, Leenders, K L, Horlock, P L, Kensett, M J, Marshall, J, Thomas, D G, Jones, T

    “…In normal brain, the blood-brain barrier (BBB) is highly impermeable to K+ cations, their transport being controlled by ATPases situated in the endothelial…”
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    Semi-automated preparation of a 11C-labelled antibiotic--[N-methyl-11C]erythromycin A lactobionate by Pike, V W, Palmer, A J, Horlock, P L, Perun, T J, Freiberg, L A, Dunnigan, D A, Liss, R H

    “…A fast semi-automated method is described for labeling the antibiotic, erythromycin A (1), with the short-lived positron-emitting radionuclide, 11C (t 1/2 =…”
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    Experience with a 82Sr/82Rb generator for clinical use by Kensett, M J, Horlock, P L, Waters, S L, Bateman, D M

    “…A 82Sr/82Rb generator system is described which is shown to be suitable for continuous intravenous infusion in man. The breakthrough of the 82Sr parent has…”
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  8. 8

    Preparation of [11C]buprenorphine--a potential radioligand for the study of the opiate receptor system in vivo by Luthra, S K, Pike, V W, Brady, F, Horlock, P L, Prenant, C, Crouzel, C

    “…A method is described for the preparation of [11C]buprenorphine in high specific activity, based on the reaction of N-(de-cyclopropylmethyl)buprenorphine with…”
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  9. 9

    Radioassay problems associated with the clinical use of a 82Rb radionuclide generator by Waters, S L, Butler, K R, Clark, J C, Horlock, P L, Kensett, M J, Goodier, I W, Makepeace, J, Smith, D, Woods, M J, Barnes, J W

    “…The short-lived positron emitting radionuclide 82Rb (t1/2 1.27 min) is conveniently available from a 82Sr/82Rb generator system. The parent nuclide (t1/2…”
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