Search Results - "Horiuchi, Yutaka"

Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution by Iwahashi, Norifusa, Umakoshi, Hironobu, Seki, Tsugio, E. Gomez-Sanchez, Celso, Mukai, Kuniaki, Suematsu, Makoto, Umezawa, Yuta, Oya, Mototsugu, Kosaka, Takeo, Seki, Masahide, Suzuki, Yutaka, Horiuchi, Yutaka, Ogawa, Yoshihiro, Nishimoto, Koshiro

“…Context: The adrenal cortex consists of zona glomerulosa (ZG), fasciculata (ZF), and reticularis. Aldosterone-producing cell clusters (APCCs) that strongly…”
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Immune Checkpoint Inhibition Followed by Tumor Infiltration of Dendritic Cells in Murine Neuro-2a Neuroblastoma by Inoue, Seiichiro, Horiuchi, Yutaka, Setoyama, Yumiko, Takeuchi, Yuta, Beck, Yoshifumi, Murakami, Takashi, Odaka, Akio

“…Most tumors responding to immunotherapy with monoclonal antibodies targeting programmed cell death protein1 (PD1) and programmed death ligand-1 (PD-L1) show…”
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Live Vaccination with Blood-Stage Plasmodium yoelii 17XNL Prevents the Development of Experimental Cerebral Malaria by Imai, Takashi, Ngo-Thanh, Ha, Suzue, Kazutomo, Shimo, Aoi, Nakamura, Akihiro, Horiuchi, Yutaka, Hisaeda, Hajime, Murakami, Takashi

“…In our work, we aim to develop a malaria vaccine with cross-strain (-species) protection. C57BL/6 mice infected with the ANKA strain (PbA) develop experimental…”
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Effect of the infectious dose and the presence of hepatitis C virus core gene on mouse intrahepatic CD8 T cells by Horiuchi, Yutaka, Takagi, Akira, Kobayashi, Nobuharu, Moriya, Osamu, Nagai, Toshinori, Moriya, Kyoji, Tsutsumi, Takeya, Koike, Kazuhiro, Akatsuka, Toshitaka

“…Aim Chronic hepatitis C viral (HCV) infections often result in ineffective CD8 T‐cell responses due to functional exhaustion of HCV‐specific T cells. However,…”
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Distinct Time Courses of Secondary Brain Damage in the Hippocampus Following Brain Concussion and Contusion in Rats by Nakajima, Yuko, Horiuchi, Yutaka, Kamata, Hiroshi, Yukawa, Masayoshi, Kuwabara, Masato, Tsubokawa, Takashi

“…Secondary brain damage (SBD) is caused by apoptosis after traumatic brain injury that is classified into concussion and contusion. Brain concussion is…”
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Relationship between regulatory and type 1 T cells in dogs with oral malignant melanoma by Horiuchi, Yutaka, Tominaga, Makiko, Ichikawa, Mika, Yamashita, Masao, Okano, Kumiko, Jikumaru, Yuri, Nariai, Yoko, Nakajima, Yuko, Kuwabara, Masato, Yukawa, Masayoshi

“…ABSTRACT Recent data suggest a decreased prevalence of IFN‐γ‐producing T lymphocytes (Type 1 T cells) in tumor‐bearing hosts. Moreover, it has been reported…”
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Increase of regulatory T cells in the peripheral blood of dogs with metastatic tumors by Horiuchi, Yutaka, Tominaga, Makiko, Ichikawa, Mika, Yamashita, Masao, Jikumaru, Yuri, Nariai, Yoko, Nakajima, Yuko, Kuwabara, Masato, Yukawa, Masayoshi

“…ABSTRACT It is well known that lymphocytes from patients with advanced‐stage cancer have impaired immune responsiveness and that type1 T lymphocyte subsets in…”
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Evaluation of immunological status in tumor-bearing dogs by Itoh, Hiroshi, Horiuchi, Yutaka, Nagasaki, Teppei, Sakonju, Iwao, Kakuta, Tomoko, Fukushima, Ushio, Uchide, Tsuyoshi, Yamashita, Mariko, Kuwabara, Masato, Yusa, Sei-ichi, Takase, Katsuaki

“…The purpose of this study was to evaluate immunological status in dogs with cancers at different stages, in comparison with normal dogs. The population of…”
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Th1/Th2 balance in canine peripheral blood lymphocytes—A flow cytometric study by Horiuchi, Yutaka, Nakajima, Yuko, Nariai, Youko, Asanuma, Hideki, Kuwabara, Masato, Yukawa, Masayoshi

“…The canine immune system undergoes continuous remodeling with advancing age. We measured the Th1/Th2 balance in peripheral blood lymphocytes (PBLs) obtained…”
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T-Helper (Th) 1/ Th2 Imbalance in the Peripheral Blood of Dogs with Malignant Tumor by Horiuchi, Yutaka, Hanazawa, Asami, Nakajima, Yuko, Nariai, Yoko, Asanuma, Hideki, Kuwabara, Masato, Yukawa, Masayoshi, Ito, Hiroshi

“…T helper type 1 cell (Th1)/Th2 imbalance has been observed in a variety of pathological conditions, including malignant diseases. We evaluated the Th1/Th2 in…”
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CD69 on Tumor-Infiltrating Cells Correlates With Neuroblastoma Suppression by Simultaneous PD-1 and PD-L1 Blockade by Inoue, Seiichiro, Takeuchi, Yuta, Horiuchi, Yutaka, Murakami, Takashi, Odaka, Akio

“…Tumor-infiltrating cells play an important role in tumor immunology, and tumor-infiltrating lymphocytes (TILs) are critical in antitumor reaction related to…”
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Characterization of the flow cytometric assay for ex vivo monitoring of cytotoxicity mediated by antigen-specific cytotoxic T lymphocytes by Takagi, Akira, Horiuchi, Yutaka, Matsui, Masanori

“…Several non-radioactive methods have widely been utilized to detect antigen-specific cytotoxic T lymphocyte (CTL) responses instead of the classical…”
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Immunological Effects of Recombinant Feline Interferon-ω (KT-80) Administration in the Dog by Kuwabara, Masato, Nariai, Youko, Horiuchi, Yutaka, Nakajima, Yuko, Yamaguchi, Yu, Horioka, Eriko, Kawanabe, Mikiko, Kubo, Takuya, Yukawa, Masayoshi, Sakai, Takeo

“…The immunological effects of recombinant feline interferon‐ω (rFeIFN‐ω; KT‐80, Toray) were examined on administration to healthy dogs. The activities of whole…”
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Infection of tumor cells with Salmonella typhimurium mimics immunogenic cell death and elicits tumor-specific immune responses by Horiuchi, Yutaka, Nakamura, Akihiro, Imai, Takashi, Murakami, Takashi

“…Some properties of -infected cells overlap with immunogenic cell death. In this study, we demonstrated that intracellular infection of melanoma with induced…”
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Blocking Monocytic Myeloid-Derived Suppressor Cell Function via Anti-DC-HIL/GPNMB Antibody Restores the In Vitro Integrity of T Cells from Cancer Patients by Kobayashi, Masato, Chung, Jin-Sung, Beg, Muhammad, Arriaga, Yull, Verma, Udit, Courtney, Kevin, Mansour, John, Haley, Barbara, Khan, Saad, Horiuchi, Yutaka, Ramani, Vijay, Harker, David, Gopal, Purva, Araghizadeh, Farshid, Cruz, Jr, Ponciano D, Ariizumi, Kiyoshi

“…Blocking the function of myeloid-derived suppressor cells (MDSC) is an attractive approach for cancer immunotherapy. Having shown DC-HIL/GPNMB to be the…”
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Targeting cryptic epitope with modified antigen coupled to the surface of liposomes induces strong antitumor CD8 T-cell immune responses in vivo by HORIUCHI, YUTAKA, TAKAGI, AKIRA, UCHIDA, TETSUYA, AKATSUKA, TOSHITAKA

“…Active cancer immunotherapy, such as cancer vaccine, is based on the fundamental knowledge that tumor-associated antigens (TAAs) are presented on MHC molecules…”
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FRI166 Characterization of Aldosterone-producing Cell Cluster (APCC) At Single-cell Resolution by Iwahashi, Norifusa, Umakoshi, Hironobu, Seki, Tsugio, Gomez-Sanchez, Celso, Mukai, Kuniaki, Suematsu, Makoto, Umezawa, Yuta, Oya, Mototsugu, Kosaka, Takeo, Seki, Masahide, Suzuki, Yutaka, Horiuchi, Yutaka, Nishimoto, Koshiro, Ogawa, Yoshihiro

“…Disclosure: N. Iwahashi: None. H. Umakoshi: None. T. Seki: None. C. Gomez-Sanchez: None. K. Mukai: None. M. Suematsu: None. Y. Umezawa: None. M. Oya: None. T…”
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Abstract 3660: Blocking the DC-HIL receptor reverses the T-cell suppression induced by proliferating myeloid-derived suppressor cells in common cancer types by Kobayashi, Masato, Chung, Jin-Sung, Beg, Muhammad, Arriaga, Yull, Verma, Udit, Courtney, Kevin, Mansour, John, Haley, Barbara, Khan, Saad, Horiuchi, Yutaka, Harker, David, Gopal, Purva, Cruz, Ponciano D., Ariizumi, Kiyoshi

“…Myeloid-derived suppressor cells (MDSC) are the most potent suppressors of T-cell function, and their exponential proliferation in cancer states counteracts…”
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Flow cytometric analysis of peripheral blood and tumor-infiltrating regulatory T cells in dogs with oral malignant melanoma by Tominaga, Makiko, Horiuchi, Yutaka, Ichikawa, Mika, Yamashita, Masao, Okano, Kumiko, Jikumaru, Yuri, Nariai, Yoko, Kadosawa, Tsuyoshi

“…It is well known that tumor-infiltrating lymphocytes (TILs) and peripheral blood lymphocytes (PBLs) from patients with advanced-stage cancer have a poor immune…”
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Effect of the infectious dose and the presence of hepatitis C virus core gene on mouse intrahepatic CD 8 T cells by Horiuchi, Yutaka, Takagi, Akira, Kobayashi, Nobuharu, Moriya, Osamu, Nagai, Toshinori, Moriya, Kyoji, Tsutsumi, Takeya, Koike, Kazuhiro, Akatsuka, Toshitaka

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