Search Results - "Horiuchi, Nobuko"

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  1. 1

    Metabolite profiling and enzyme reaction phenotyping of luseogliflozin, a sodium-glucose cotransporter 2 inhibitor, in humans by Miyata, Atsunori, Hasegawa, Masatoshi, Hachiuma, Kenji, Mori, Haruyuki, Horiuchi, Nobuko, Mizuno-Yasuhira, Akiko, Chino, Yukihiro, Jingu, Shigeji, Sakai, Soichi, Samukawa, Yoshishige, Nakai, Yasuhiro, Yamaguchi, Jun-ichi

    Published in Xenobiotica (01-04-2017)
    “…1. To understand the clearance mechanism of luseogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, we investigated its human metabolite profile…”
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    Journal Article
  2. 2

    Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats by Tanaka, Yu, Omura, Tomohiro, Fukasawa, Misako, Horiuchi, Nobuko, Miyata, Noriyuki, Minagawa, Toshiya, Yoshida, Shigeru, Nakaike, Shiro

    Published in Neuroscience research (01-12-2007)
    “…TS-011, a potent and selective inhibitor of 20-HETE synthesis, has been described as providing significant benefits in animal stroke models. However, no…”
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    Journal Article
  3. 3

    Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent by Hasegawa, Masatoshi, Chino, Yukihiro, Horiuchi, Nobuko, Hachiuma, Kenji, Ishida, Masahiro, Fukasawa, Yoshiki, Nakai, Yasuhiro, Yamaguchi, Jun-ichi

    Published in Xenobiotica (02-12-2015)
    “…1. We investigated the metabolism and disposition of luseogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, in rats and dogs, as well as in vitro…”
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    Journal Article
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    Stereoselectivity and Species Difference in Plasma Protein Binding of KE-298 and Its Metabolites by ENDO, Hiromi, YOSHIDA, Hideo, HASEGAWA, Masatoshi, OHMI, Naoko, HORIUCHI, Nobuko, HAMADA, Yuka, HIGUCHI, Shohei

    Published in Biological & pharmaceutical bulletin (01-07-2001)
    “…In vitro protein binding of KE-298 and its plasma metabolites, deacetyl-KE-298 (M-1) and S-methyl-KE-298 (M-2), was high in rat (>97%), dog (>89%) and human…”
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    Journal Article
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    An odontological study on Down's syndrome. Part 3: Dental caries of the deciduous teeth by Takeda, Y, Horiuchi, N, Nakata, M

    “…The dental caries experience of a sample of 97 children with Down's syndrome who had deciduous dentition was contrasted with that of 57 non affected healthy…”
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    Journal Article
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    The United States Department of Education, 1981-1985: Agenda for abolishment by Horiuchi, Ellen Nobuko

    Published 01-01-1990
    “…A reflection of the conservative American populace was captured in the Republican Platform of 1980, when President-elect Ronald Reagan promised to abolish the…”
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    Dissertation