Search Results - "Horiuchi, Nobuko"
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Metabolite profiling and enzyme reaction phenotyping of luseogliflozin, a sodium-glucose cotransporter 2 inhibitor, in humans
Published in Xenobiotica (01-04-2017)“…1. To understand the clearance mechanism of luseogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, we investigated its human metabolite profile…”
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Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats
Published in Neuroscience research (01-12-2007)“…TS-011, a potent and selective inhibitor of 20-HETE synthesis, has been described as providing significant benefits in animal stroke models. However, no…”
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Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent
Published in Xenobiotica (02-12-2015)“…1. We investigated the metabolism and disposition of luseogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, in rats and dogs, as well as in vitro…”
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Stereoselectivity and Species Difference in Plasma Protein Binding of KE-298 and Its Metabolites
Published in Biological & pharmaceutical bulletin (01-07-2001)“…In vitro protein binding of KE-298 and its plasma metabolites, deacetyl-KE-298 (M-1) and S-methyl-KE-298 (M-2), was high in rat (>97%), dog (>89%) and human…”
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Temporary anti-cancer & anti-pain effects of mechanical stimulation of any one of 3 front teeth (1st incisor, 2nd incisor, & canine) of right & left side of upper & lower jaws and their possible mechanism, & relatively long term disappearance of pain & cancer parameters by one optimal dose of DHEA, Astragalus, Boswellia Serrata, often with press needle stimulation of True ST. 36
Published in Acupuncture & electro-therapeutics research (2009)“…One minute downward pressure on the tip of any one of the front 3 teeth (1st incisor, 2nd incisor, and canine) at the right and left sides of the upper and…”
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An odontological study on Down's syndrome. Part 3: Dental caries of the deciduous teeth
Published in Shoni shikagaku zasshi = the Japanese journal of pedodontics (1989)“…The dental caries experience of a sample of 97 children with Down's syndrome who had deciduous dentition was contrasted with that of 57 non affected healthy…”
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The United States Department of Education, 1981-1985: Agenda for abolishment
Published 01-01-1990“…A reflection of the conservative American populace was captured in the Republican Platform of 1980, when President-elect Ronald Reagan promised to abolish the…”
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Dissertation