Search Results - "Horiuchi, Amanda"
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Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1
Published in PloS one (23-06-2020)“…The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the…”
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PERM1 regulates energy metabolism in the heart via ERRα/PGC-1α axis
Published in Frontiers in cardiovascular medicine (07-11-2022)“…PERM1 is a striated muscle-specific regulator of mitochondrial bioenergetics. We previously demonstrated that PERM1 is downregulated in the failing heart and…”
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Abstract 286: Smyd1 is Required for Cell Survival During Glucose Deprivation
Published in Circulation research (02-08-2019)“…Abstract only Our recent study demonstrated that the histone methyltransferase Smyd1 positively regulates cardiac metabolism through transcriptional control of…”
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Abstract 289: Perm1 is a Novel Regulator of Cardiac Energetics and Function
Published in Circulation research (31-07-2020)“…Abstract only Regulation of mitochondrial energetics is key to maintain cardiac function. Perm1 ( P GC-1 and E RR- r egulator, m uscle 1 ) was previously shown…”
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