Search Results - "Horiot, Catherine"

Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment–Drug Conjugates (FDCs) by Jolivet, Louis, Ait Mohamed Amar, Imène, Horiot, Catherine, Boursin, Fanny, Colas, Cyril, Letast, Stéphanie, Denevault-Sabourin, Caroline, Allard-Vannier, Emilie, Joubert, Nicolas, Aubrey, Nicolas

“…Antibody–drug conjugates (ADCs) derived from a full immunoglobulin-G (IgG) are associated with suboptimal solid-tumor penetration and Fc-mediated toxicities…”
Get full text

Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality by Aubrey, Nicolas, Gouilleux-Gruart, Valérie, Dhommée, Christine, Mariot, Julie, Boursin, Fanny, Albrecht, Nicolas, Bergua, Cécile, Croix, Cécile, Gilotin, Mäelle, Haudebourg, Eloi, Horiot, Catherine, Matthias, Laetitia, Mouline, Caroline, Lajoie, Laurie, Munos, Audrey, Ferry, Gilles, Viaud-Massuard, Marie-Claude, Thibault, Gilles, Velge-Roussel, Florence

“…Bispecific antibodies (BsAbs) represent an important advance in innovative therapeutic strategies. Among the countless formats of BsAbs, fusion with molecules…”
Get full text

Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences by Cnudde, Thomas, Lakhrif, Zineb, Bourgoin, Justine, Boursin, Fanny, Horiot, Catherine, Henriquet, Corinne, di Tommaso, Anne, Juste, Matthieu Olivier, Jiacomini, Isabella Gizzi, Dimier-Poisson, Isabelle, Pugnière, Martine, Mévélec, Marie-Nöelle, Aubrey, Nicolas

“…In order to increase the successful development of recombinant antibodies and fragments, it seems fundamental to enhance their expression and/or biophysical…”
Get full text

Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability by Marchalot, Anne, Horiot, Catherine, Lambert, Jean-Marie, Carrion, Claire, Oblet, Christelle, Pollet, Justine, Cogné, Michel, Moreau, Jeanne, Laffleur, Brice, Delpy, Laurent

“…Allergy regroups numerous complex and various diseases classified as IgE-dependent or non–IgE-dependent hypersensitivities. IgEs are expressed as membrane and…”
Get full text

Intra-Domain Cysteines by Jolivet, Louis, Ait Mohamed Amar, Imène, Horiot, Catherine, Boursin, Fanny, Colas, Cyril, Letast, Stéphanie, Denevault-Sabourin, Caroline, Allard-Vannier, Emilie, Joubert, Nicolas, Aubrey, Nicolas

“…Antibody–drug conjugates (ADCs) derived from a full immunoglobulin-G (IgG) are associated with suboptimal solid-tumor penetration and Fc-mediated toxicities…”
Get full text