Search Results - "Horimoto, Yasumi"
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Conserved prosegment residues stabilize a late-stage folding transition state of pepsin independently of ground states
Published in PloS one (01-07-2014)“…The native folding of certain zymogen-derived enzymes is completely dependent upon a prosegment domain to stabilize the folding transition state, thereby…”
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Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum
Published in Journal of structural biology (01-07-2011)“…Plasmepsin I (PMI) is one of the four vacuolar pepsin-like proteases responsible for hemoglobin degradation by the malarial parasite Plasmodium falciparum, and…”
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Raman Spectroscopic Study of Changes in Fish Actomyosin during Setting
Published in Journal of agricultural and food chemistry (01-08-1999)“…Actomyosins (AMs) isolated from tilapia, lemon sole, ling cod, and rock fish were heated at 40 °C, and structural changes in AMs were investigated using Raman…”
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Effects of different proteases on iron absorption property of egg white hydrolysates
Published in Food research international (01-05-2017)“…One of the causes of iron deficiency in human is poor absorption of non-heme iron from the diet. While proteins from meats have been reported in the literature…”
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Understanding the Mechanism of Prosegment-catalyzed Folding by Solution NMR Spectroscopy
Published in The Journal of biological chemistry (10-01-2014)“…Multidomain protein folding is often more complex than a two-state process, which leads to the spontaneous folding of the native state. Pepsin, a…”
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Influence of aggregation on the antioxidative capacity of milk peptides
Published in International dairy journal (01-07-2012)“…This study investigated the effects of pH and addition of genistein prior to freeze-drying on the aggregation of reconstituted antioxidative milk peptides. The…”
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1H, 13C, and 15N backbone resonance assignments of the porcine pepsin and porcine pepsin complexed with pepstatin
Published in Biomolecular NMR assignments (01-04-2014)“…Pepsin is formed as the zymogen, pepsinogen, which includes an additional 44 residue prosegment (PS) on the N-terminus. Upon acidification (pH <3) the PS is…”
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sup 1^H, ^sup 13^C, and ^sup 15^N backbone resonance assignments of the porcine pepsin and porcine pepsin complexed with pepstatin
Published in Biomolecular NMR assignments (01-04-2014)“…Pepsin is formed as the zymogen, pepsinogen, which includes an additional 44 residue prosegment (PS) on the N-terminus. Upon acidification (pH <3) the PS is…”
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Multifunctional aspartic peptidase prosegments
Published in New biotechnology (01-06-2009)“…The structure-function relationships of aspartic peptidases (APs) (EC 3.4.23.X) have been extensively investigated, yet much remains to be elucidated regarding…”
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H, ¹³C, and ¹⁵N backbone resonance assignments of the porcine pepsin and porcine pepsin complexed with pepstatin
Published in Biomolecular NMR assignments (01-04-2014)“…Pepsin is formed as the zymogen, pepsinogen, which includes an additional 44 residue prosegment (PS) on the N-terminus. Upon acidification (pH <3) the PS is…”
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Recombinant prosegment peptide acts as a folding catalyst and inhibitor of native pepsin
Published in Biochimica et biophysica acta (01-12-2009)“…Porcine pepsin A, a gastric aspartic peptidase, is initially produced as the zymogen pepsinogen that contains an N-terminal, 44 residue prosegment (PS) domain…”
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Rational redesign of porcine pepsinogen containing an antimicrobial peptide
Published in Protein engineering, design and selection (01-09-2010)“…A novel strategy for the controlled release and localization of bioactive peptides within digestive and immunity-related enzymes was developed. The N-terminus…”
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Classification of Microbial Defects in Milk Using a Dynamic Headspace Gas Chromatograph and Computer-Aided Data Processing. 2. Artificial Neural Networks, Partial Least-Squares Regression Analysis, and Principal Component Regression Analysis
Published in Journal of agricultural and food chemistry (17-03-1997)“…Objective, yet cost-effective evaluation of flavor is difficult in quality control of milk. Inexpensive gas chromatographs in conjunction with computer models…”
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Classification of Microbial Defects in Milk Using a Dynamic Headspace Gas Chromatograph and Computer-Aided Data Processing. 1. Principal Component Similarity Analysis
Published in Journal of agricultural and food chemistry (01-03-1997)“…There is a need for reliable objective tests for the detection of off-flavors of milk, some of which are caused by bacteriological growth. The objective of the…”
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Solid Phase Microextraction/Gas Chromatography of Salmonella-Infected Beef
Published in Journal of agricultural and food chemistry (01-06-2000)“…Eight strains of Salmonellae were incubated in TSB culture medium at 37 °C for 24 h. Volatile compounds derived from the bacteria were collected using…”
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Rational redesign of porcine pepsinogen containing an antimicrobial peptide
Published in Protein engineering (01-09-2010)“…A novel strategy for the controlled release and localization of bioactive peptides within digestive and immunity-related enzymes was developed. The N-terminus…”
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Partial least-squares regression of fourth-derivative ultraviolet absorbance spectra predicts composition of protein mixtures: application to bovine caseins
Published in Journal of agricultural and food chemistry (01-09-1994)“…A method is described for the quantitative determination of the composition of protein mixtures using fourth-derivative ultraviolet spectroscopy. The…”
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