Search Results - "Horimoto, Andrea R. V. R."

Ancestry-driven metabolite variation provides insights into disease states in admixed populations by Reynolds, Kaylia M, Horimoto, Andrea R V R, Lin, Bridget M, Zhang, Ying, Kurniansyah, Nuzulul, Yu, Bing, Boerwinkle, Eric, Qi, Qibin, Kaplan, Robert, Daviglus, Martha, Hou, Lifang, Zhou, Laura Y, Cai, Jianwen, Shaikh, Saame Raza, Sofer, Tamar, Browning, Sharon R, Franceschini, Nora

“…Metabolic pathways are related to physiological functions and disease states and are influenced by genetic variation and environmental factors…”
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Distribution and heritability of diurnal preference (chronotype) in a rural Brazilian family-based cohort, the Baependi study by von Schantz, Malcolm, Taporoski, Tamara P., Horimoto, Andréa R. V. R., Duarte, Nubia E., Vallada, Homero, Krieger, José E., Pedrazzoli, Mario, Negrão, André B., Pereira, Alexandre C.

“…Diurnal preference (chronotype) is a useful instrument for studying circadian biology in humans. It harbours trait-like dimensions relating to circadian period…”
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A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set by Santos, Hadassa C, Horimoto, Andréa V R, Tarazona-Santos, Eduardo, Rodrigues-Soares, Fernanda, Barreto, Mauricio L, Horta, Bernardo L, Lima-Costa, Maria F, Gouveia, Mateus H, Machado, Moara, Silva, Thiago M, Sanches, José M, Esteban, Nubia, Magalhaes, Wagner C S, Rodrigues, Maíra R, Kehdy, Fernanda S G, Pereira, Alexandre C

“…The Brazilian population is considered to be highly admixed. The main contributing ancestral populations were European and African, with Amerindians…”
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Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics by Horimoto, Andréa R V R, Xue, Diane, Thornton, Timothy A, Blue, Elizabeth E

“…Genetic studies have primarily been conducted in European ancestry populations, identifying dozens of loci associated with late-onset Alzheimer's disease (AD)…”
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Compared Heritability of Chronotype Instruments in a Single Population Sample by Leocadio-Miguel, Mario A., Ruiz, Francieli S., Ahmed, Sabrina S., Taporoski, Tâmara P., Horimoto, Andréa R. V. R., Beijamini, Felipe, Pedrazzoli, Mario, Knutson, Kristen L., Pereira, Alexandre C., von Schantz, Malcolm

“…It is well established that the oldest chronotype questionnaire, the morningness-eveningness questionnaire (MEQ), has significant heritability, and several…”
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Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population by Egan, Kieren J, Campos Santos, Hadassa, Beijamini, Felipe, Duarte, Núbia E, Horimoto, Andréa R V R, Taporoski, Tâmara P, Vallada, Homero, Negrão, André B, Krieger, José E, Pedrazzoli, Mário, Knutson, Kristen L, Pereira, Alexandre C, von Schantz, Malcolm

“…Significant questions remain unanswered regarding the genetic versus environmental contributions to racial/ethnic differences in sleep and circadian rhythms…”
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Shared Genetic Factors of Anxiety and Depression Symptoms in a Brazilian Family-Based Cohort, the Baependi Heart Study by Taporoski, Tâmara P, Negrão, André B, Horimoto, Andréa R V R, Duarte, Nubia E, Alvim, Rafael O, de Oliveira, Camila M, Krieger, José E, Schantz, Malcolm von, Vallada, Homero, Pereira, Alexandre C

“…To investigate the phenotypic and genetic overlap between anxiety and depression symptoms in an admixed population from extended family pedigrees. Participants…”
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Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics by Blue, Elizabeth E., Horimoto, Andréa R.V.R., Mukherjee, Shubhabrata, Wijsman, Ellen M., Thornton, Timothy A.

“…Although the relationship between APOE and Alzheimer's disease (AD) is well established in populations of European descent, the effects of APOE and ancestry on…”
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A genome-wide association study of asthma symptoms in Latin American children by Costa, Gustavo N O, Dudbridge, Frank, Fiaccone, Rosemeire L, da Silva, Thiago M, Conceição, Jackson S, Strina, Agostino, Figueiredo, Camila A, Magalhães, Wagner C S, Rodrigues, Maira R, Gouveia, Mateus H, Kehdy, Fernanda S G, Horimoto, Andrea R V R, Horta, Bernardo, Burchard, Esteban G, Pino-Yanes, Maria, Del Rio Navarro, Blanca, Romieu, Isabelle, Hancock, Dana B, London, Stephanie, Lima-Costa, Maria Fernanda, Pereira, Alexandre C, Tarazona, Eduardo, Rodrigues, Laura C, Barreto, Mauricio L

“…Asthma is a chronic disease of the airways and, despite the advances in the knowledge of associated genetic regions in recent years, their mechanisms have yet…”
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Race, Ancestry, and Disease Outcomes in Black Individuals: a Clarification by Horimoto, Andrea R.V.R., Franceschini, Nora

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Serum metabolomics profile of type 2 diabetes mellitus in a Brazilian rural population by Padilha, Kallyandra, Venturini, Gabriela, de Farias Pires, Thiago, Horimoto, Andréa R. V. R., Malagrino, Pamella Araujo, Gois, Tamiris Carneiro, Kiers, Bianca, Oliveira, Camila Maciel, de Oliveira Alvim, Rafael, Blatt, Celso, Krieger, José Eduardo, Pereira, Alexandre Costa

“…Introduction The development of common forms of diabetes comes from the interaction between environmental and genetic factors, and the consequences of poor…”
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Genome-wide analysis in Brazilian Xavante Indians reveals low degree of admixture by Kuhn, Patricia C, Horimoto, Andréa R V Russo, Sanches, José Maurício, Vieira Filho, João Paulo B, Franco, Luciana, Fabbro, Amaury Dal, Franco, Laercio Joel, Pereira, Alexandre C, Moises, Regina S

“…Characterization of population genetic variation and structure can be used as tools for research in human genetics and population isolates are of great…”
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Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort by Loesch, Douglas, Horimoto, Andrea R.V.R., Sarihan, Elif Irem, Inca-Martinez, Miguel, Mason, Emily, Cornejo-Olivas, Mario, Torres, Luis, Mazzetti, Pilar, Cosentino, Carlos, Sarapura-Castro, Elison, Rivera-Valdivia, Andrea, Medina, Angel C., Dieguez, Elena, Raggio, Victor, Lescano, Andres, Tumas, Vitor, Borges, Vanderci, Ferraz, Henrique B., Rieder, Carlos R., Schumacher-Schuh, Artur, Santos-Lobato, Bruno L., Velez-Pardo, Carlos, Jimenez-Del-Rio, Marlene, Lopera, Francisco, Moreno, Sonia, Chana-Cuevas, Pedro, Fernandez, William, Arboleda, Gonzalo, Arboleda, Humberto, Arboleda-Bustos, Carlos E., Yearout, Dora, Zabetian, Cyrus P., Thornton, Timothy A., Mata, Ignacio F., O'Connor, Timothy D.

“…Large-scale Parkinson's disease (PD) genome-wide association studies (GWAS) have, until recently, only been conducted on subjects with European-ancestry…”
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Heritability of arterial stiffness in a Brazilian population: Baependi Heart Study by Alvim, Rafael O, Horimoto, Andréa R.V.R, Oliveira, Camila M, Bortolotto, Luiz A, Krieger, José E, Pereira, Alexandre C

“…BACKGROUND:Increased arterial stiffness is an important determinant of cardiovascular disease risk. In addition, it has been recognized that arterial stiffness…”
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Admixture Mapping of Chronic Kidney Disease and Risk Factors in Hispanic/Latino Individuals From Central America Country of Origin by Horimoto, Andrea R V R, Sun, Quan, Lash, James P, Daviglus, Martha L, Cai, Jianwen, Haack, Karin, Cole, Shelley A, Thornton, Timothy A, Browning, Sharon R, Franceschini, Nora

“…Chronic kidney disease (CKD) is highly prevalent in Central America, and genetic factors may contribute to CKD risk. To understand the influences of genetic…”
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Polygenic risk scores and kidney traits in the Hispanic/Latino population: The Hispanic Community Health Study/Study of Latinos by Zhou, Laura Y., Sofer, Tamar, Horimoto, Andrea R.V.R., Talavera, Gregory A., Lash, James P., Cai, Jianwen, Franceschini, Nora

“…Estimated glomerular filtration rate (eGFR) is used to evaluate kidney function and determine the presence of chronic kidney disease (CKD), a highly prevalent…”
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante by Leite, Lanna C.G., dos Santos, Marcia C., Duarte, Nubia E., Horimoto, Andrea R.V.R., Crispim, Felipe, Vieira Filho, João Paulo B., Dal Fabbro, Amaury L., Franco, Laércio J., Moises, Regina S.

“…Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different…”
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Heritability of OSA in a Rural Population by de Paula, Lilian K.G., PT, Alvim, Rafael O., PT, Pedrosa, Rodrigo P., MD, PhD, Horimoto, Andrea R.V.R., PhD, Krieger, José E., MD, PhD, Oliveira, Camila M., MD, PhD, Pereira, Alexandre C., MD, PhD, Lorenzi-Filho, Geraldo, MD, PhD

“…Background OSA has a familial aggregation pattern indicating that it can be partially caused by a genetic component. However, the heritability of OSA has been…”
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Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations by Horimoto, Andrea R.V.R., Boyken, Lisa A., Blue, Elizabeth E., Grinde, Kelsey E., Nafikov, Rafael A., Sohi, Harkirat K., Nato, Alejandro Q., Bis, Joshua C., Brusco, Luis I., Morelli, Laura, Ramirez, Alfredo, Dalmasso, Maria Carolina, Temple, Seth, Satizabal, Claudia, Browning, Sharon R., Seshadri, Sudha, Wijsman, Ellen M., Thornton, Timothy A.

“…Alzheimer disease (AD) is the most common form of senile dementia, with high incidence late in life in many populations including Caribbean Hispanic (CH)…”
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Cohort profile: the Baependi Heart Study—a family-based, highly admixed cohort study in a rural Brazilian town by Egan, Kieren J, von Schantz, Malcolm, Negrão, André B, Santos, Hadassa C, Horimoto, Andréa R V R, Duarte, Nubia E, Gonçalves, Guilherme C, Soler, Júlia M P, de Andrade, Mariza, Lorenzi-Filho, Geraldo, Vallada, Homero, Taporoski, Tâmara P, Pedrazzoli, Mario, Azambuja, Ana P, de Oliveira, Camila M, Alvim, Rafael O, Krieger, José E, Pereira, Alexandre C

“…PurposeCardiovascular disease (CVD) is a major challenge to global health. The same epidemiological transition scenario is replayed as countries develop, but…”
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