Search Results - "Horii, Motoki"

Suppression of IL-23-mediated psoriasis-like inflammation by regulatory B cells by Mizumaki, Kie, Horii, Motoki, Kano, Miyu, Komuro, Akito, Matsushita, Takashi

“…Psoriasis is an inflammatory cutaneous disease mediated by T-cell dependent immune responses; however, B cells are also considered to play an important role…”
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Immunomodulating role of the JAKs inhibitor tofacitinib in a mouse model of bleomycin-induced scleroderma by Aung, Wah Wah, Wang, Chenyang, Xibei, Jia, Horii, Motoki, Mizumaki, Kie, Kano, Miyu, Okamura, Ai, Kobayashi, Tadahiro, Matsushita, Takashi

“…Janus kinase (JAK)-signal transducer and activator of transcription (STAT) was hyperactivated in biopsies from patients with systemic sclerosis (SSc) and in…”
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Authors' reply to “a case of juvenile amyopathic dermatomyositis with anti‐transcription intermediary factor 1‐α antibody showing negative anti‐TIF1‐γ ELISA results: Comment on the article by Mizumaki et al.” by Matsushita, Takashi, Fushida, Natsumi, Horii, Motoki, Mizumaki, Kie

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The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis by Wang, Chenyang, Oishi, Kyosuke, Kobayashi, Tadahiro, Fujii, Ko, Horii, Motoki, Fushida, Natsumi, Kitano, Tasuku, Maeda, Shintaro, Ikawa, Yuichi, Komuro, Akito, Hamaguchi, Yasuhito, Matsushita, Takashi

“…The bleomycin-induced scleroderma model is a well-established and dependable method for creating a mouse model of SSc (systemic sclerosis). In the field of…”
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Stevens–Johnson syndrome associated with radiation recall dermatitis in a patient treated with immune checkpoint inhibitor by Horii, Motoki, Kobayashi, Tadahiro, Maeda, Shintaro, Takehara, Kazuhiko, Matsushita, Takashi

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Cytokine‐producing B‐cell balance associates with skin fibrosis in patients with systemic sclerosis by Horii, Motoki, Fushida, Natsumi, Ikeda, Tomoyuki, Oishi, Kyosuke, Hamaguchi, Yasuhito, Ikawa, Yuichi, Komuro, Akito, Matsushita, Takashi

“…Systemic sclerosis (SSc) is an autoimmune disease characterized by skin and lung fibrosis. Over 90% of patients with SSc are positive for autoantibodies. In…”
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Comprehensive autoantibody profiling in systemic autoimmunity by a highly-sensitive multiplex protein array by Kuzumi, Ai, Norimatsu, Yuta, Matsuda, Kazuki M., Ono, Chihiro, Okumura, Taishi, Kogo, Emi, Goshima, Naoki, Fukasawa, Takemichi, Fushida, Natsumi, Horii, Motoki, Yamashita, Takashi, Yoshizaki-Ogawa, Asako, Yamaguchi, Kei, Matsushita, Takashi, Sato, Shinichi, Yoshizaki, Ayumi

“…Comprehensive autoantibody evaluation is essential for the management of autoimmune disorders. However, conventional methods suffer from poor sensitivity, low…”
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Case of pembrolizumab‐induced dermatomyositis with anti‐transcription intermediary factor 1‐γ antibody by Mizumaki, Kie, Makino, Satoshi, Ikawa, Yuka, Maeda, Shintaro, Horii, Motoki, Fushida, Natsumi, Hamaguchi, Yasuhito, Nohara, Takahiro, Izumi, Koji, Matsushita, Takashi

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FcγRIIB inhibits inflammation in a murine model of psoriasis by Nakabori, Irisu, Hamaguchi, Yasuhito, Sawada, Kaori, Horii, Motoki, Fushida, Natsumi, Kitano, Tasuku, Chenyang, Wang, Xibei, Jia, Ikawa, Yuichi, Komuro, Akito, Matsushita, Takashi

“…Psoriasis is a chronic, inflammatory cutaneous disease. FcγRIIB is a low-affinity receptor for the IgG Fc fragment that provides a negative feedback pathway to…”
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Early improvement of nailfold videocapillaroscopy abnormalities in dermatomyositis patients with anti‐NXP‐2 antibody by Mugii, Naoki, Hamaguchi, Yasuhito, Fushida, Natsumi, Horii, Motoki, Kitano, Tasuku, Fujii, Ko, Sawada, Kaori, Oishi, Kyosuke, Maeda, Shintaro, Matsushita, Takashi

“…This study aimed to evaluate long‐term changes in nailfold videocapillaroscopy (NVC) findings in dermatomyositis patients with antinuclear matrix protein 2…”
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Regulatory B cells and T cell Regulation in Cancer by Horii, Motoki, Matsushita, Takashi

“…[Display omitted] •There are two opposing B cell subsets; effector B cells and regulatory B cells.•Effector B cells have an ability to promote anti-tumor…”
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Anifrolumab for systemic lupus erythematosus: A clinical study of Japanese patients in Kanazawa University Hospital by Fushida, Natsumi, Horii, Motoki, Oishi, Kyosuke, Matsushita, Takashi

“…We investigated the effectiveness of anifrolumab in treating systemic lupus erythematosus (SLE). We treated seven patients with SLE (age range, 31–68 years;…”
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Longitudinal changes in nailfold videocapillaroscopy findings differ by myositis-specific autoantibody in idiopathic inflammatory myopathy by Mugii, Naoki, Hamaguchi, Yasuhito, Horii, Motoki, Fushida, Natsumi, Ikeda, Tomoyuki, Oishi, Kyosuke, Yahata, Tetsutarou, Someya, Fujiko, Matsushita, Takashi

“…To assess the longitudinal changes in nailfold videocapillaroscopy (NVC) in patients expressing myositis-specific autoantibodies [anti-aminoacyl-tRNA…”
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A case of digital papillary adenocarcinoma with human papillomavirus 42 detected by Imazaki, Katsuya, Oishi, Kyosuke, Horii, Motoki, Shimizu, Kyoko, Maeda, Shintaro, Komura, Kazuhiro, Anzawa, Kazushi, Shimizu, Akira, Matsushita, Takashi

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Absence of interstitial lung disease at initial visit may predict a favorable outcome for Japanese patients with systemic sclerosis with anti–topoisomerase I antibody by Hamaguchi, Yasuhito, Yoshimura, Yukari, Horii, Motoki, Fushida, Natsumi, Kitano, Tasuku, Sawada, Kaori, Oishi, Kyosuke, Maeda, Shintaro, Watanabe, Satoshi, Matsushita, Takashi

“…Interstitial lung disease (ILD) is recognized a prognostic factor and leading cause of death in patients with systemic sclerosis (SSc). The aim of the present…”
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Clinical features of patients with connective tissue disease with anti–human upstream binding factor antibodies: A single‐center retrospective study by Fushida, Natsumi, Horii, Motoki, Fujii, Ko, Mizumaki, Kie, Kitano, Tasuku, Sawada, Kaori, Numata, Natsuki, Oishi, Kyosuke, Maeda, Shintaro, Hamaguchi, Yasuhito, Watanabe, Satoshi, Matsushita, Takashi

“…Anti–human upstream‐binding factor (anti‐hUBF) antibodies have been reported predominantly in patients with connective tissue diseases (CTDs); these have also…”
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Stevens-Johnson syndrome associated with radiation recall dermatitis in a patient treated with immune checkpoint inhibitor by Horii, Motoki, Kobayashi, Tadahiro, Maeda, Shintaro, Takehara, Kazuhiko, Matsushita, Takashi

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