Search Results - "Horie, Minoru"

Extensive Diversity of Molecular Mechanisms Underlying the Congenital Long QT Syndrome Type 1 by Horie, Minoru

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Genetic and Clinical Advances in Congenital Long QT Syndrome by Mizusawa, Yuka, Horie, Minoru, Wilde, Arthur AM

“…Congenital long QT syndrome (LQTS) is an inherited arrhythmia syndrome characterized by a prolonged QT interval on the 12-lead ECG, torsades de pointes and a…”
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Phenotypic Manifestations of Mutations in Genes Encoding Subunits of Cardiac Potassium Channels by Shimizu, Wataru, Horie, Minoru

“…Since 1995, when a potassium channel gene, hERG (human ether-à-go-go-related gene), now referred to as KCNH2, encoding the rapid component of cardiac delayed…”
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Correction: Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients by Ohno, Seiko, Hasegawa, Kanae, Horie, Minoru

“…[This corrects the article DOI: 10.1371/journal.pone.0131517.]…”
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HRS/EHRA/APHRS Expert Consensus Statement on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes by Priori, Silvia G., MD PhD, Wilde, Arthur A., MD, PhD, Horie, Minoru, MD, PhD, Cho, Yongkeun, MD, PhD, Behr, Elijah R., MA, MBBS, MD, FRCP, Berul, Charles, MD, FHRS, CCDS, Blom, Nico, MD, PhD, Brugada, Josep, MD, PhD, Chiang, Chern-En, MD, PhD, Huikuri, Heikki, MD, Kannankeril, Prince, MD, Krahn, Andrew, MD, FHRS, Leenhardt, Antoine, MD, Moss, Arthur, MD, Schwartz, Peter J, Shimizu, Wataru, MD, PhD, Tomaselli, Gordon, MD, FHRS, Tracy, Cynthia, MD

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J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge by Antzelevitch, Charles, PhD, FHRS, Yan, Gan-Xin, MD, PhD, Ackerman, Michael J., MD, PhD, Borggrefe, Martin, MD, Corrado, Domenico, MD, PhD, Guo, Jihong, MD, Gussak, Ihor, MD, PhD, Hasdemir, Can, MD, Horie, Minoru, MD, Huikuri, Heikki, MD, Ma, Changsheng, MD, Morita, Hiroshi, MD, PhD, Nam, Gi-Byoung, MD, PhD, Sacher, Frederic, MD, PhD, Shimizu, Wataru, MD, PhD, Viskin, Sami, MD, Wilde, Arthur A.M., MD, PhD, FHRS

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Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients by Ohno, Seiko, Hasegawa, Kanae, Horie, Minoru

“…Catecholaminergic polymorphic ventricular tachycardia (CPVT) is one of the causes of sudden cardiac death in young people and results from RYR2 mutations in…”
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The genetics underlying acquired long QT syndrome: impact for genetic screening by Itoh, Hideki, Crotti, Lia, Aiba, Takeshi, Spazzolini, Carla, Denjoy, Isabelle, Fressart, Véronique, Hayashi, Kenshi, Nakajima, Tadashi, Ohno, Seiko, Makiyama, Takeru, Wu, Jie, Hasegawa, Kanae, Mastantuono, Elisa, Dagradi, Federica, Pedrazzini, Matteo, Yamagishi, Masakazu, Berthet, Myriam, Murakami, Yoshitaka, Shimizu, Wataru, Guicheney, Pascale, Schwartz, Peter J, Horie, Minoru

“…Acquired long QT syndrome (aLQTS) exhibits QT prolongation and Torsades de Pointes ventricular tachycardia triggered by drugs, hypokalaemia, or bradycardia…”
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Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1　― Modified Schwartz Score by Ozawa, Junichi, Ohno, Seiko, Fujii, Yusuke, Makiyama, Takeru, Suzuki, Hiroshi, Saitoh, Akihiko, Horie, Minoru

“…Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been often misdiagnosed as long QT syndrome (LQTS) type 1 (LQT1), which…”
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An NGS-based genotyping in LQTS; minor genes are no longer minor by Ohno, Seiko, Ozawa, Junichi, Fukuyama, Megumi, Makiyama, Takeru, Horie, Minoru

“…Mutations in KCNQ1, KCNH2, and SCN5A are the major cause of long QT syndrome (LQTS). More than 90% of the genotyped patients have been reported to carry…”
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Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a Ryanodine Receptor Type 2 Missense Mutation by Nozaki, Yoshihiro, Kato, Yoshiaki, Uike, Kiyoshi, Yamamura, Kenichiro, Kikuchi, Masahiro, Yasuda, Maki, Ohno, Seiko, Horie, Minoru, Murayama, Takashi, Kurebayashi, Nagomi, Horigome, Hitoshi

“…Background:Left ventricular non-compaction (LVNC) is a cardiomyopathy characterized by prominent trabeculae and intertrabecular recesses. We present the cases…”
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Bradycardia Is a Specific Phenotype of Catecholaminergic Polymorphic Ventricular Tachycardia Induced by RYR2 Mutations by Miyata, Kazuaki, Ohno, Seiko, Itoh, Hideki, Horie, Minoru

“…Objective Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal inherited disease characterized by ventricular arrhythmias induced by…”
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Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy by Freyermuth, Fernande, Rau, Frédérique, Kokunai, Yosuke, Linke, Thomas, Sellier, Chantal, Nakamori, Masayuki, Kino, Yoshihiro, Arandel, Ludovic, Jollet, Arnaud, Thibault, Christelle, Philipps, Muriel, Vicaire, Serge, Jost, Bernard, Udd, Bjarne, Day, John W., Duboc, Denis, Wahbi, Karim, Matsumura, Tsuyoshi, Fujimura, Harutoshi, Mochizuki, Hideki, Deryckere, François, Kimura, Takashi, Nukina, Nobuyuki, Ishiura, Shoichi, Lacroix, Vincent, Campan-Fournier, Amandine, Navratil, Vincent, Chautard, Emilie, Auboeuf, Didier, Horie, Minoru, Imoto, Keiji, Lee, Kuang-Yung, Swanson, Maurice S., de Munain, Adolfo Lopez, Inada, Shin, Itoh, Hideki, Nakazawa, Kazuo, Ashihara, Takashi, Wang, Eric, Zimmer, Thomas, Furling, Denis, Takahashi, Masanori P., Charlet-Berguerand, Nicolas

“…Myotonic dystrophy (DM) is caused by the expression of mutant RNAs containing expanded CUG repeats that sequester muscleblind-like (MBNL) proteins, leading to…”
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Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture by Kamakura, Tsukasa, Makiyama, Takeru, Sasaki, Kenichi, Yoshida, Yoshinori, Wuriyanghai, Yimin, Chen, Jiarong, Hattori, Tetsuhisa, Ohno, Seiko, Kita, Toru, Horie, Minoru, Yamanaka, Shinya, Kimura, Takeshi

“…Background: In the short- to mid-term, cardiomyocytes generated from human-induced pluripotent stem cells (hiPSC-CMs) have been reported to be less mature than…”
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Molecular genetics have opened a new era for arrhythmia research, but also Pandora's box? by Horie, Minoru

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Functionally validated SCN5A variants allow interpretation of pathogenicity and prediction of lethal events in Brugada syndrome by Ishikawa, Taisuke, Kimoto, Hiroki, Mishima, Hiroyuki, Yamagata, Kenichiro, Ogata, Soshiro, Aizawa, Yoshiyasu, Hayashi, Kenshi, Morita, Hiroshi, Nakajima, Tadashi, Nakano, Yukiko, Nagase, Satoshi, Murakoshi, Nobuyuki, Kowase, Shinya, Ohkubo, Kimie, Aiba, Takeshi, Morimoto, Shimpei, Ohno, Seiko, Kamakura, Shiro, Nogami, Akihiko, Takagi, Masahiko, Karakachoff, Matilde, Dina, Christian, Schott, Jean-Jacques, Yoshiura, Koh-Ichiro, Horie, Minoru, Shimizu, Wataru, Nishimura, Kunihiro, Kusano, Kengo, Makita, Naomasa

“…Abstract Aims The prognostic value of genetic variants for predicting lethal arrhythmic events (LAEs) in Brugada syndrome (BrS) remains controversial. We…”
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Molecular pathogenesis of long QT syndrome type 1 by Wu, Jie, PhD, Ding, Wei-Guang, MD, PhD, Horie, Minoru, MD, PhD

“…Abstract Long QT syndrome type 1 (LQT1) is a subtype of a congenital cardiac syndrome caused by mutation in the KCNQ1 gene, which encodes the α- subunit of the…”
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Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome by Yoshinaga, Masao, Ninomiya, Yumiko, Tanaka, Yuji, Fukuyama, Megumi, Kato, Koichi, Ohno, Seiko, Horie, Minoru, Ogata, Hiromitsu

“…Background: This study was performed to clarify the clinical findings of pediatric patients diagnosed with long QT syndrome (LQTS) through electrocardiographic…”
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Genetics of Brugada syndrome by Juang, Jyh-Ming Jimmy, M.D., MS2, Ph.D, Horie, Minoru

“…Abstract In 1992, the Brugada syndrome (BrS) was recognized as a disease responsible for sudden cardiac death, characterized by a right bundle-branch block…”
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Efficacy of Antiarrhythmic Drugs Short-Term Use After Catheter Ablation for Atrial Fibrillation (EAST-AF) trial by Kaitani, Kazuaki, Inoue, Koichi, Kobori, Atsushi, Nakazawa, Yuko, Ozawa, Tomoya, Kurotobi, Toshiya, Morishima, Itsuro, Miura, Fumiharu, Watanabe, Tetsuya, Masuda, Masaharu, Naito, Masaki, Fujimoto, Hajime, Nishida, Taku, Furukawa, Yoshio, Shirayama, Takeshi, Tanaka, Mariko, Okajima, Katsunori, Yao, Takenori, Egami, Yasuyuki, Satomi, Kazuhiro, Noda, Takashi, Miyamoto, Koji, Haruna, Tetsuya, Kawaji, Tetsuma, Yoshizawa, Takashi, Toyota, Toshiaki, Yahata, Mitsuhiko, Nakai, Kentaro, Sugiyama, Hiroaki, Higashi, Yukei, Ito, Makoto, Horie, Minoru, Kusano, Kengo F, Shimizu, Wataru, Kamakura, Shiro, Morimoto, Takeshi, Kimura, Takeshi, Shizuta, Satoshi

“…Substantial portion of early arrhythmia recurrence after catheter ablation for atrial fibrillation (AF) is considered to be due to irritability in left atrium…”
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