Search Results - "Horie, Asuka"
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Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells
Published in Biopharmaceutics & drug disposition (01-12-2014)“…ABSTRACT The aim of the present study was to investigate the membrane transport mechanisms of choline using human intestinal epithelial LS180 cells. The mRNA…”
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Variability of Bioavailability and Intestinal Absorption Mechanisms of Metoprolol
Published in DRUG METABOLISM AND PHARMACOKINETICS (2014)“…We previously reported that aging and/or cytochrome P450 2D6 polymorphism are responsible for the interindividual variability in the systemic clearance (CL)…”
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Membrane Transport Mechanisms of Quinidine and Procainamide in Renal LLC-PK1 and Intestinal LS180 Cells
Published in Biological & Pharmaceutical Bulletin (2010)“…The aim of the present study was to compare the membrane transport mechanisms of procainamide with those of quinidine using renal epithelial LLC-PK1 and…”
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Variability of Bioavailability and Intestinal Absorption Characteristics of Bisoprolol
Published in DRUG METABOLISM AND PHARMACOKINETICS (2013)“…We previously reported that renal function is partly responsible for the interindividual variability of the pharmacokinetics of bisoprolol. The aim of the…”
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Pharmacokinetic variability of flecainide in younger Japanese patients and mechanisms for renal excretion and intestinal absorption
Published in Biopharmaceutics & drug disposition (01-04-2014)“…ABSTRACT The aims of the present study were to evaluate the variability of pharmacokinetics of flecainide in young Japanese patients and to investigate the…”
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Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells
Published in Biopharmaceutics & drug disposition (01-07-2011)“…ABSTRACT The aim of the present study was to investigate the mechanisms for membrane transport of metformin in human intestinal epithelial Caco‐2 cells. The…”
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Presence of an H+/Quinidine Antiport System in Madin–Darby Canine Kidney Cells
Published in European journal of drug metabolism and pharmacokinetics (01-12-2016)“…Background and Objectives We have recently found an H + /quinidine antiport system in human kidney HEK 293 cells. The aim of the present study was to evaluate…”
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