Search Results - "Hori, Kei"

Neuronal Migration and AUTS2 Syndrome by Hori, Kei, Hoshino, Mikio

“…Neuronal migration is one of the pivotal steps to form a functional brain, and disorganization of this process is believed to underlie the pathology of…”
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AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders by Hori, Kei, Shimaoka, Kazumi, Hoshino, Mikio

“…Neurodevelopmental disorders (NDDs), including autism spectrum disorders (ASD) and intellectual disability (ID), are a large group of neuropsychiatric…”
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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140 by Ambrozkiewicz, Mateusz C., Schwark, Manuela, Kishimoto-Suga, Mika, Borisova, Ekaterina, Hori, Kei, Salazar-Lázaro, Andrea, Rusanova, Alexandra, Altas, Bekir, Piepkorn, Lars, Bessa, Paraskevi, Schaub, Theres, Zhang, Xin, Rabe, Tamara, Ripamonti, Silvia, Rosário, Marta, Akiyama, Haruhiko, Jahn, Olaf, Kobayashi, Tatsuya, Hoshino, Mikio, Tarabykin, Victor, Kawabe, Hiroshi

“…The establishment of axon-dendrite polarity is fundamental for radial migration of neurons during cortex development of mammals. We demonstrate that the E3…”
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Association of blood pressure after peritoneal dialysis initiation with the decline rate of residual kidney function in newly-initiated peritoneal dialysis patients by Kuroki, Yusuke, Hori, Kei, Tsuruya, Kazuhiko, Matsuo, Dai, Mitsuiki, Koji, Hirakata, Hideki, Nakano, Toshiaki, Kitazono, Takanari

“…Background Lower blood pressure (BP) levels are linked to a slower decline of kidney function in patients with chronic kidney disease (CKD) without kidney…”
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Glycosphingolipid metabolic reprogramming drives neural differentiation by Russo, Domenico, Della Ragione, Floriana, Rizzo, Riccardo, Sugiyama, Eiji, Scalabrì, Francesco, Hori, Kei, Capasso, Serena, Sticco, Lucia, Fioriniello, Salvatore, De Gregorio, Roberto, Granata, Ilaria, Guarracino, Mario R, Maglione, Vittorio, Johannes, Ludger, Bellenchi, Gian Carlo, Hoshino, Mikio, Setou, Mitsutoshi, D'Esposito, Maurizio, Luini, Alberto, D'Angelo, Giovanni

“…Neural development is accomplished by differentiation events leading to metabolic reprogramming. Glycosphingolipid metabolism is reprogrammed during neural…”
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Cytoskeletal Regulation by AUTS2 in Neuronal Migration and Neuritogenesis by Hori, Kei, Nagai, Taku, Shan, Wei, Sakamoto, Asami, Taya, Shinichiro, Hashimoto, Ryoya, Hayashi, Takashi, Abe, Manabu, Yamazaki, Maya, Nakao, Keiko, Nishioka, Tomoki, Sakimura, Kenji, Yamada, Kiyofumi, Kaibuchi, Kozo, Hoshino, Mikio

“…Mutations in the Autism susceptibility candidate 2 gene (AUTS2), whose protein is believed to act in neuronal cell nuclei, have been associated with multiple…”
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Brain Atrophy in Peritoneal Dialysis and CKD Stages 3-5: A Cross-sectional and Longitudinal Study by Tsuruya, Kazuhiko, MD, PhD, Yoshida, Hisako, MSc, Kuroki, Yusuke, MD, Nagata, Masaharu, MD, PhD, Mizumasa, Tohru, MD, Mitsuiki, Koji, MD, PhD, Yoshiura, Takashi, MD, PhD, Hirakawa, Makoto, MD, PhD, Kanai, Hidetoshi, MD, PhD, Hori, Kei, MD, PhD, Hirakata, Hideki, MD, PhD, Kitazono, Takanari, MD, PhD

“…Background Brain atrophy has been reported in patients with end-stage renal disease receiving hemodialysis, although its mechanism is unknown. However, little…”
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Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation by Dewa, Ken-ichi, Arimura, Nariko, Kakegawa, Wataru, Itoh, Masayuki, Adachi, Toma, Miyashita, Satoshi, Inoue, Yukiko U., Hizawa, Kento, Hori, Kei, Honjoya, Natsumi, Yagishita, Haruya, Taya, Shinichiro, Miyazaki, Taisuke, Usui, Chika, Tatsumoto, Shoji, Tsuzuki, Akiko, Uetake, Hirotomo, Sakai, Kazuhisa, Yamakawa, Kazuhiro, Sasaki, Takuya, Nagai, Jun, Kawaguchi, Yoshiya, Sone, Masaki, Inoue, Takayoshi, Go, Yasuhiro, Ichinohe, Noritaka, Kaibuchi, Kozo, Watanabe, Masahiko, Koizumi, Schuichi, Yuzaki, Michisuke, Hoshino, Mikio

“…In the central nervous system, astrocytes enable appropriate synapse function through glutamate clearance from the synaptic cleft; however, it remains unclear…”
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Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory by Hori, Kei, Nagai, Taku, Shan, Wei, Sakamoto, Asami, Abe, Manabu, Yamazaki, Maya, Sakimura, Kenji, Yamada, Kiyofumi, Hoshino, Mikio

“…Mutations in the Autism susceptibility candidate 2 gene (AUTS2) have been associated with a broad range of psychiatric illnesses including autism spectrum…”
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Potential involvement of DSCAML1 mutations in neurodevelopmental disorders by Ogata, Shigehiro, Hashizume, Koichi, Hayase, Yoneko, Kanno, Yukie, Hori, Kei, Balan, Shabeesh, Yoshikawa, Takeo, Takahashi, Hidehiko, Taya, Shinichiro, Hoshino, Mikio

“…The molecular mechanisms underlying neurodevelopmental disorders (NDDs) remain unclear. We previously identified Down syndrome cell adhesion molecule like 1…”
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AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication by Yamashiro, Kunihiko, Hori, Kei, Lai, Esther S.K., Aoki, Ryo, Shimaoka, Kazumi, Arimura, Nariko, Egusa, Saki F., Sakamoto, Asami, Abe, Manabu, Sakimura, Kenji, Watanabe, Takaki, Uesaka, Naofumi, Kano, Masanobu, Hoshino, Mikio

“…Autism susceptibility candidate 2 (AUTS2), a risk gene for autism spectrum disorders (ASDs), is implicated in telencephalon development. Because AUTS2 is also…”
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GABAergic Neuron Specification in the Spinal Cord, the Cerebellum, and the Cochlear Nucleus by Hori, Kei, Hoshino, Mikio

“…In the nervous system, there are a wide variety of neuronal cell types that have morphologically, physiologically, and histochemically different…”
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Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system by Kim, Euiseok J., Hori, Kei, Wyckoff, Alex, Dickel, Lauren K., Koundakjian, Edmund J., Goodrich, Lisa V., Johnson, Jane E.

“…Neurog1 (Ngn1, Neurod3, neurogenin1) is a basic helix‐loop‐helix (bHLH) transcription factor essential for neuronal differentiation and subtype specification…”
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A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord by Bröhl, Dominique, Strehle, Michael, Wende, Hagen, Hori, Kei, Bormuth, Ingo, Nave, Klaus-Armin, Müller, Thomas, Birchmeier, Carmen

“…Dorsal horn neurons express many different neuropeptides that modulate sensory perception like the sensation of pain. Inhibitory neurons of the dorsal horn…”
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AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication by Hori, Kei, Yamashiro, Kunihiko, Nagai, Taku, Shan, Wei, Egusa, Saki F., Shimaoka, Kazumi, Kuniishi, Hiroshi, Sekiguchi, Masayuki, Go, Yasuhiro, Tatsumoto, Shoji, Yamada, Mitsuyo, Shiraishi, Reika, Kanno, Kouta, Miyashita, Satoshi, Sakamoto, Asami, Abe, Manabu, Sakimura, Kenji, Sone, Masaki, Sohya, Kazuhiro, Kunugi, Hiroshi, Wada, Keiji, Yamada, Mitsuhiko, Yamada, Kiyofumi, Hoshino, Mikio

“…Impairments in synapse development are thought to cause numerous psychiatric disorders. Autism susceptibility candidate 2 (AUTS2) gene has been associated with…”
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A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling by Hori, Kei, Cholewa-Waclaw, Justyna, Nakada, Yuji, Glasgow, Stacey M, Masui, Toshihiko, Henke, R Michael, Wildner, Hendrik, Martarelli, Benedetta, Beres, Thomas M, Epstein, Jonathan A, Magnuson, Mark A, Macdonald, Raymond J, Birchmeier, Carmen, Johnson, Jane E

“…Neural networks are balanced by inhibitory and excitatory neuronal activity. The formation of these networks is initially generated through neuronal subtype…”
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Origin of a Non-Clarke’s Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function by Yuengert, Rachel, Hori, Kei, Kibodeaux, Erin E., McClellan, Jacob X., Morales, Justin E., Huang, Teng-Wei P., Neul, Jeffrey L., Lai, Helen C.

“…Proprioception, the sense of limb and body position, is essential for generating proper movement. Unconscious proprioceptive information travels through…”
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An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation by Inoue, Yukiko U, Morimoto, Yuki, Yamada, Mayumi, Kaneko, Ryosuke, Shimaoka, Kazumi, Oki, Shinji, Hotta, Mayuko, Asami, Junko, Koike, Eriko, Hori, Kei, Hoshino, Mikio, Imayoshi, Itaru, Inoue, Takayoshi

“…Fluorescent reporter mouse lines and Cre/Flp recombinase driver lines play essential roles in investigating various molecular functions . Now that applications…”
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Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord by Henke, R Michael, Savage, Trisha K, Meredith, David M, Glasgow, Stacey M, Hori, Kei, Dumas, Judy, MacDonald, Raymond J, Johnson, Jane E

“…PTF1-J is a trimeric transcription factor complex essential for generating the correct balance of GABAergic and glutamatergic interneurons in multiple regions…”
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Involvement of the Phosphatidylinositol 3-Kinase/Rac1 and Cdc42 Pathways in Radial Migration of Cortical Neurons by Konno, Daijiro, Yoshimura, Saori, Hori, Kei, Maruoka, Hisato, Sobue, Kenji

“…During cortical development, newly generated neurons migrate radially toward their final positions. Although several candidate genes essential for this radial…”
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