Search Results - "Horan, P J"

Antinociceptive profile of biphalin, a dimeric enkephalin analog by Horan, P J, Mattia, A, Bilsky, E J, Weber, S, Davis, T P, Yamamura, H I, Malatynska, E, Appleyard, S M, Slaninova, J, Misicka, A

“…The dimeric enkephalin biphalin (Try-D-Ala-Gly-Phe-NH)2 was evaluated in mice using antinociceptive, gastrointestinal and physical dependence paradigms and…”
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Comparative pharmacological and biochemical studies between butorphanol and morphine by Horan, P J, Ho, I K

“…A number of in vivo and in vitro studies were undertaken to compare the pharmacological and biochemical effects of the partial agonist, butorphanol, with that…”
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Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse by Horan, P J, de Costa, B R, Rice, K, Haaseth, R C, Hruby, V J, Porreca, F

“…In these studies, the antagonistic actions of (-)-1-Cyclopentyl-5-(1,2,3,4,5,-hexahydro-8-hydroxy-3,6,11-trimethyl-2,6 -methano-3-benzazocin-11-yl)-3-pentanone…”
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Lack of cross-tolerance between U69,593 and bremazocine suggests kappa-opioid receptor multiplicity in mice by Horan, P J, Porreca, F

“…The development of tolerance, and the possibility of cross-tolerance, to the kappa-opioid receptor-mediated antinociceptive effects of U69,593 and bremazocine…”
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Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity by Horan, P J, Wild, K D, Misicka, A, Lipkowski, A, Haaseth, R C, Hruby, V J, Weber, S J, Davis, T P, Yamamura, H I, Porreca, F

“…Pharmacological evidence has suggested the presence of two supraspinal opioid delta receptor subtypes in the mouse, termed delta-1 and delta-2…”
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Acute and Long-term Response of the Meniscus to Partial Meniscectomy Using the Holmium:YAG Laser by Horan, Patrick J., Popovic, Neven A., Islinger, Richard B., Kuklo, Timothy R., Dick, Edward J., McKinney, LuAnn

“…The purpose of this study was to evaluate the histological effects of holmium:YAG laser partial meniscectomy in an in vivo rabbit model and compare it with…”
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[L-Ala3]DPDPE: A New Enkephalin Analog with a Unique Opioid Receptor Activity Profile. Further Evidence of .delta.-Opioid Receptor Multiplicity by Haaseth, Ronald C, Horan, Peter J, Bilsky, Edward J, Davis, Peg, Zalewska, Teresa, Slaninova, Jirina, Yamamura, Henry I, Weber, Steven J, Davis, Thomas P

“…To investigate delta-opioid receptor topography near the 3-position of [D-Pen2,D-Pen5]enkephalin (DPDPE), a series of small-group 3-position analogs of DPDPE…”
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Langerhans' cell histiocytosis in patients older than 21 years by Islinger, R B, Kuklo, T R, Owens, B D, Horan, P J, Choma, T J, Murphey, M D, Temple, H T

“…In this retrospective review of 541 patients with Langerhans' cell histiocytosis, 211 (39%) patients were older than 21 years of age, whereas 330 (61%) were…”
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A review of total joint replacement in active duty soldiers by KUKLO, T. R, HEEKIN, R. D, TEMPLE, H. T, ISLINGER, R. B, HORAN, P. J

“…Thirty-two active duty soldiers (36 total joint replacements) were followed from 9 months and 18 years (average 4.1 years) to evaluate the outcome of total…”
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Unexpected antinociceptive potency of cyclic [D-Tca1]CTAP: potential for a novel mechanism of action by Horan, P J, Wild, K D, Kazmierski, W M, Ferguson, R, Hruby, V J, Weber, S J, Davis, T P, Fang, L, Knapp, R J, Yamamura, H I

“…This study tested the hypothesis that compounds which may bind simultaneously to delta and mu receptors may be more potent antinociceptive agents than would be…”
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Pseudoirreversible binding characteristics of [D-Ala2,Glu4]deltorphin and its Cys4 substituted derivative to delta-opioid receptors by Wild, K D, Horan, P J, Misicka, A, Lipkowski, A, Haaseth, R C, Matsunaga, T O, Hruby, V J, Toth, G, Borsodi, A, Yamamura, H I

“…Following the identification of [D-Ala2,Glu4]deltorphin as a selective delta 2-opioid receptor agonist in vivo, we synthesized the Cys4-substituted analogue as…”
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