Search Results - "Hopwood, A"

Synergy and Contingency as Driving Forces for the Evolution of Multiple Secondary Metabolite Production by Streptomyces Species by Challis, Gregory L., Hopwood, David A.

“…In this article we briefly review theories about the ecological roles of microbial secondary metabolites and discuss the prevalence of multiple secondary…”
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Soil to genomics: the Streptomyces chromosome by Hopwood, David A

“…The 8-9-Mb Streptomyces chromosome is linear, with a "core" containing essential genes and "arms" carrying conditionally adaptive genes that can sustain large…”
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Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces by Rigali, Sébastien, Titgemeyer, Fritz, Barends, Sharief, Mulder, Suzanne, Thomae, Andreas, Hopwood, David, van Wezel, Gilles

“…Members of the soil‐dwelling prokaryotic genus Streptomyces produce many secondary metabolites, including antibiotics and anti‐tumour agents. Their formation…”
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Genetic Contributions to Understanding Polyketide Synthases by Hopwood, David A

“…Hopwood discusses the historical view of the understanding of the polyketide synthases acquired via genetic approaches…”
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The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR‐family regulator DasR and links N‐acetylglucosamine metabolism to the control of development by Rigali, Sébastien, Nothaft, Harald, Noens, Elke E. E., Schlicht, Maximilian, Colson, Sévrine, Müller, Marisa, Joris, Bernard, Koerten, Henk K., Hopwood, David A., Titgemeyer, Fritz, Van Wezel, Giles P.

“…Summary Members of the soil‐dwelling, sporulating prokaryotic genus Streptomyces are indispensable for the recycling of the most abundant polysaccharides on…”
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Imaging mass spectrometry reveals highly specific interactions between actinomycetes to activate specialized metabolic gene clusters by Hopwood, David A

“…The genomes of actinomycetes contain numerous gene clusters potentially able to encode the production of many antibiotics and other specialized metabolites…”
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Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint by Perera, David, Tilston, Valerie, Hopwood, Jane A., Barchi, Marco, Boot-Handford, Raymond P., Taylor, Stephen S.

“…Bub1 is a component of the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures genome stability by delaying anaphase until all the…”
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Highlights of Streptomyces genetics by Hopwood, David A

“…Sixty years ago, the actinomycetes, which include members of the genus Streptomyces, with their bacterial cellular dimensions but a mycelial growth habit like…”
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Nonbelieved Memories in The False Memory Archive by Otgaar, Henry, Bücken, Charlotte, Bogaard, Glynis, Wade, Kimberley A., Hopwood, A. R., Scoboria, Alan, Howe, Mark L.

“…The False Memory Archive is a unique art collection containing hundreds of false memory reports submitted by members of the general population. The current…”
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Low-power microwave plasma source based on a microstrip split-ring resonator by Iza, F., Hopwood, J.A.

“…Microplasma sources can be integrated into portable devices for applications such as bio-microelectromechanical system sterilization, small-scale materials…”
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Forty years of genetics with Streptomyces: from in vivo through in vitro to in silico by Hopwood, David A

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Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes by Santi, Daniel V, Menzella, Hugo G, Reid, Ralph, Carney, John R, Chandran, Sunil S, Reisinger, Sarah J, Patel, Kedar G, Hopwood, David A

“…Type I polyketide synthase (PKS) genes consist of modules ∼3-6 kb long, which encode the structures of 2-carbon units in polyketide products. Alteration or…”
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A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome by Redenbach, M, Kieser, H M, Denapaite, D, Eichner, A, Cullum, J, Kinashi, H, Hopwood, D A

“…A Supercos-1 library carrying chromosomal DNA of a plasmid-free derivative of Streptomyces coelicolor A3(2) was organized into an ordered encyclopaedia of…”
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Engineered Biosynthesis of Novel Polyketides by McDaniel, Robert, Ebert-Khosla, Susanne, Hopwood, David A., Khosla, Chaitan

“…Polyketide synthases (PKSs) are multifunctional enzymes that catalyze the biosynthesis of a huge variety of carbon chains differing in their length and…”
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Argon Microplasma Diagnostics by Diode Laser Absorption by Miura, N, Jun Xue, Hopwood, J A

“…The densities of argon excited states (1s 3 , 1s 4 , and 1s 5 ) and the gas temperature of argon microplasma were measured by diode laser absorption. A 900-MHz…”
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Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits by McDaniel, Robert, Ebert-Khosla, Susanne, Hopwood, David A, Khosla, Chaitan

“…Recent advances in understanding of bacterial aromatic polyketide biosynthesis allow the development of a set of design rules for the rational manipulation of…”
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FEASIBILITY AND SAFETY OF HM II TO HVAD VS. HM II TO HM II EXCHANGE STRATEGY FOR PUMP THROMBOSIS by Davey, R.A, Agarwal, R, Raina, A, Hopwood, A, Sokos, G, Murali, S, Bailey, S, Benza, R.L

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How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them by Hopwood, David A

“…Acquired antibiotic resistance among dangerous bacterial pathogens is an increasing medical problem. While in Mycobacterium tuberculosis this occurs by…”
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Microwave-Frequency Effects on Microplasma by Jun Xue, Hopwood, J.A.

“…Capacitively coupled microplasma generation becomes more efficient at microwave frequencies. Helium and argon microplasmas are characterized using excitation…”
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A microfabricated inductively coupled plasma generator by Hopwood, J.A.

“…The design, fabrication, and characterization of a surface micromachined plasma generator is described for the first time in this paper. The plasma is…”
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