Search Results - "Hopson, Jessika"
-
1
Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages
Published in The Journal of biological chemistry (18-12-2009)“…Alveolar macrophages (AMs) play a major role in host defense against microbial infections in the lung. To perform this function, these cells must ingest and…”
Get full text
Journal Article -
2
The Granular Chloride Channel ClC-3 Is Permissive for Insulin Secretion
Published in Cell metabolism (01-10-2009)“…Insulin secretion from pancreatic β cells is dependent on maturation and acidification of the secretory granule, processes necessary for prohormone convertase…”
Get full text
Journal Article -
3
Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms
Published in The Journal of neuroscience (30-06-2010)“…The two proteases beta-secretase and gamma-secretase generate the amyloid beta peptide and are drug targets for Alzheimer's disease. Here we tested the…”
Get full text
Journal Article -
4
Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands
Published in Journal of medicinal chemistry (22-01-2009)“…Both μ-opioid (MOP) and type 2 cholecystokinin (CCK2) receptors are present in areas of the central nervous system that are involved in modulation of pain…”
Get full text
Journal Article