Search Results - "Hoppensteadt, Debra A"

Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims by Pandey, Ghanshyam N, Rizavi, Hooriyah S, Ren, Xinguo, Fareed, Jawed, Hoppensteadt, Debra A, Roberts, Rosalinda C, Conley, Robert R, Dwivedi, Yogesh

“…Abstract Teenage suicide is a major public health concern, but its neurobiology is not well understood. Proinflammatory cytokines play an important role in…”
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Comparison of Platelet Function and Morphology in Patients Undergoing Percutaneous Coronary Intervention Receiving Bivalirudin Versus Unfractionated Heparin Versus Clopidogrel Pretreatment and Bivalirudin by Anand, Sunil X., MD, Kim, Michael C., MD, Kamran, Mazullah, MD, Sharma, Samin K., MD, Kini, Annapoorna S., MD, Fareed, Jawed, PhD, Hoppensteadt, Debra A., PhD, Carbon, Frank, MD, Cavusoglu, Erdal, MD, Varon, David, MD, Viles-Gonzalez, Juan F., MD, Badimon, Juan J., PhD, Marmur, Jonathan D., MD

“…We hypothesized that direct thrombin inhibition could attenuate platelet activation and release of soluble CD40 ligand (sCD40L), a marker of inflammation,…”
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The Relationship Between the Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia by Hoppensteadt, Debra A., PhD, SH, MT(ASCP), Walenga, Jeanine M., PhD

“…Antiphospholipid syndrome (APS) and heparin-induced thrombocytopenia (HIT) are immune-mediated thrombotic conditions caused by antibodies targeted to a…”
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The Association of Pain With Protein Inflammatory Biomarkers: A Review of the Literature by DeVon, Holli A, Piano, Mariann R, Rosenfeld, Anne G, Hoppensteadt, Debra A

“…BACKGROUND:Pain is a key diagnostic criterion in many medical conditions. In the absence of self-reported pain, measurement of a proxy for pain, such as an…”
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In vivo neutralization of unfractionated heparin and low-molecular-weight heparin by a novel salicylamide derivative by Kuziej, Jacqueline, Litinas, Evangelos, Hoppensteadt, Debra A, Liu, Dahui, Walenga, Jeanine M, Fareed, Jawed, Jeske, Walter

“…Unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) are widely used anticoagulants for surgical and interventional use. Currently, the…”
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Preparation and anticoagulant activity of the phosphosulfomannan PI-88 by Yu, Guangli, Gunay, Nur Sibel, Linhardt, Robert J, Toida, Toshihiko, Fareed, Jawed, Hoppensteadt, Debra A, Shadid, Hazar, Ferro, Vito, Li, Caiping, Fewings, Kym, Palermo, Maria C, Podger, Denis

“…A yeast-derived phosphomannan mixture was chemically sulfonated and the composition and structure of the product mixture was studied. This phosphosulfomannan…”
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Usefulness of intravenous enoxaparin for percutaneous coronary intervention in stable angina pectoris by Rabah, Maher M, Premmereur, Jerome, Graham, Mariann, Fareed, Jawed, Hoppensteadt, Debra A, Grines, Lorelie L, Grines, Cindy L

“…This pilot study was designed to determine whether the low molecular weight heparin, enoxaparin, could be used for elective percutaneous coronary intervention…”
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Laboratory Evaluation of the Antiphospholipid Syndrome by Hoppensteadt, Debra A., PhD, SH, MT(ASCP), Fabbrini, Nancy, MT(ASCP), Bick, Rodger L., MD, PhD, Messmore, Harry L., MD, Adiguzel, Cafar, MD, Fareed, Jawed, PhD, FAHA

“…Antiphospholipid syndrome (APLS) is among the most common acquired blood protein defects that have been identified as leading to thrombosis. This article…”
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A heparin-like compound isolated from a marine crab rich in glucuronic acid 2-O-sulfate presents low anticoagulant activity by Andrade, Giulianna P.V., Lima, Marcelo A., de Souza, Airton A., Fareed, Jawed, Hoppensteadt, Debra A., Santos, Elizeu A., Chavante, Suely F., Oliveira, Fernanda W., Rocha, Hugo A.O., Nader, Helena B.

“…► Report of a crab heparin-like compound rich in 2-O-sulfated glucuronic acid units. ► COSY, TOCSY, NOESY and HSQC were used to trace the spin systems of the…”
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Effect of erythropoietin stimulating agents on vascular endothelial growth factor levels in patients with end stage renal disease by Saluk, Jennifer L, Bansal, Vinoid K, Hoppensteadt, Debra A, Syed, Daneyal A, Abro, Schuarazad, Fareed, Jawed

“…End stage renal disease (ESRD) is a debilitating disease that not only impacts quality of life, but also increases the risk of cardiovascular disease, stroke,…”
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Differential effects of clivarin and heparin in patients undergoing hip and knee surgery for the generation of anti-heparin-platelet factor 4 antibodies by Ahmad, Sarfraz, Haas, Sylvia, Hoppensteadt, Debra A, Lietz, Helen, Reid, Ulrike, Bender, Norbert, Messmore, Harry L, Misselwitz, Frank, Bacher, Peter, Gaikwad, Bhavna S, Jeske, Walter P, Walenga, Jeanine M, Fareed, Jawed

“…The pathophysiology of heparin-induced thrombocytopenia (HIT) syndrome is mediated via a heterogeneous group of heparin(s)-platelet factor 4 (H-PF4) complexes…”
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Survival of heparins, oral anticoagulants, and aspirin after the year 2010 by Fareed, Jawed, Hoppensteadt, Debra A, Fareed, Daniel, Demir, Muzaffer, Wahi, Rakesh, Clarke, Melaine, Adiguzel, Cafer, Bick, Rodger

“…The conventional management of thrombotic and cardiovascular disorders is based on the use of heparin, oral anticoagulants, and aspirin. Despite remarkable…”
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DIFFERENTIAL MODULATION OF COAGULATION AND FIBRINOLYSIS BY NEW ORAL ANTICOAGULANTS. PHARMACOLOGIC IMPLICATIONS by Hoppensteadt, Debra A, Cunanan, Josephine, Iqbal, Omer, Gray, Angel, Lewis, Bruce, Walenga, Jeanine, Fareed, Jawed

“…Conclusion Thus the major differences between the Dabigatran and Rivaroxiban is the inhibitory effect on the target enzyme, thrombin generation and it's…”
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Management of thrombotic and cardiovascular disorders in the new millenium by Fareed, Jawed, Hoppensteadt, Debra A, Bick, Rodger L

“…Anticoagulants and antithrombotic drugs have played a key role in the prophylaxis, treatment and surgica/interventional management of thrombotic and…”
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Inflammatory and Metabolic Syndrome Biomarker Analysis of Vascular Outcomes in End-stage Renal Disease by Sweigert, Patrick J., Bansal, Vinod K., Hoppensteadt, Debra A., Saluk, Jennifer L., Syed, Daneyal A., Fareed, Jawed

“…Abstract End-stage renal disease (ESRD) presents a complex syndrome in which inflammatory and metabolic processes contribute to disease progression and…”
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Anticoagulant and Antithrombotic Actions of AVE5026, an Enriched Anti-Xa Hemisynthetic Ultra-Low-Molecular-Weight Heparin by Hoppensteadt, Debra A, Gray, Angel, Jeske, Walter P, Walenga, Jeanine M, Fareed, Jawed

“…AVE5026 represents a new generation of ultra-low-molecular-weight heparin (LMWH) with high anti-Xa and low anti-IIa activities (anti Xa-IIa ratio >30). In…”
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Differentiating low-molecular-weight heparins based on chemical, biological, and pharmacologic properties: implications for the development of generic versions of low-molecular-weight heparins by Jeske, Walter P, Walenga, Jeanine M, Hoppensteadt, Debra A, Vandenberg, Curtis, Brubaker, Aleah, Adiguzel, Cafer, Bakhos, Mamdouh, Fareed, Jawed

“…Low-molecular-weight heparins (LMWHs) are polypharmacologic drugs used to treat thrombotic and cardiovascular disorders. These drugs are manufactured using…”
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Pharmacology of argatroban by Jeske, Walter P, Fareed, Jawed, Hoppensteadt, Debra A, Lewis, Bruce, Walenga, Jeanine M

“…Argatroban is a synthetic, small-molecule direct thrombin inhibitor that is approved in the USA, the EU and Japan for prophylaxis or treatment of thrombosis in…”
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Effects of a synthetic factor Xa inhibitor (JTV-803) on various laboratory tests by Tobu, Mahmut, Iqbal, Omer, Hoppensteadt, Debra A, Shultz, Christopher, Jeske, Walter, Fareed, Jawed

“…Synthetic direct inhibitors of factor Xa are capable of prolonging the global anticoagulant assay times in a concentration-dependent fashion. The relative…”
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Generic low-molecular-weight heparins: some practical considerations by Fareed, Jawed, Leong, Wendy L, Hoppensteadt, Debra A, Jeske, Walter P, Walenga, Jeanine, Wahi, Raisesh, Bick, Rodger L

“…It is now widely accepted that various low-molecular-weight heparins (LMWHs) exhibit specific molecular and structural attributes that are determined by the…”
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